Sara C. Kozma - Publications, H-index & Citations

Sara C. Kozma

University System of Ohio

61H指数

202论文数

2.3W被引数

收录论文 51

发表时间

Dual requirement for a newly identified phosphorylation site in p70(s6k)

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

OAAI

Moser, BA; Dennis, PB; Pullen, N; Pearson, RB; Williamson, NA; Wettenhall, REH; Kozma, SC; Thomas, G

S6K1-/-/S6K2-/- mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

763

OAAI

Pende, M; Um, SH; Mieulet, V; Sticker, M; Goss, VL; Mestan, J; Mueller, M; Fumagalli, S; Kozma, SC; Thomas, G

Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

490

OAAI

Gangloff, YG; Mueller, M; Dann, SG; Svoboda, P; Sticker, M; Spetz, JF; Um, SH; Brown, EJ; Cereghini, S; Thomas, G; Kozma, SC

A heat-sensitive Arabidopsis thaliana kinase substitutes for human p70s6k function in vivo

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Turck, F; Kozma, SC; Thomas, G; Nagy, F

Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)-and Ribosomal Protein S6K-Mediated Signals

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Kroczynska, Barbara; Kaur, Surinder; Katsoulidis, Efstratios; Majchrzak-Kita, Beata; Sassano, Antonella; Kozma, Sara C.; Fish, Eleanor N.; Platanias, Leonidas C.

A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis 一种针对S6K1的化合物可阻止脂肪量的增加并减轻饮食引起的肝骨质疏松

JCI INSIGHT

IF6.1

2022-07-22

OAAI

Lluch, Aina; Veiga, Sonia R.; Latorre, Jessica; Moreno-Navarrete, Jose M.; Bonifaci, Nuria; Nguyen, Van Dien; Zhou, You; Hoering, Marcus; Liebisch, Gerhard; Olkkonen, Vesa M.; Llobet-Navas, David; Thomas, George; Rodriguez-Barrueco, Ruth; Fernandez-Real, Jose M.; Kozma, Sara C.; Ortega, Francisco J.

Nucleotide depletion reveals the impaired ribosome biogenesis checkpoint as a barrier against DNA damage

EMBO JOURNAL

IF8.3

2020-06-02

OAAI

Pelletier, Joffrey; Riano-Canalias, Ferran; Almacellas, Eugenia; Mauvezin, Caroline; Samino, Sara; Feu, Sonia; Menoyo, Sandra; Domostegui, Ana; Garcia-Cajide, Marta; Salazar, Ramon; Cortes, Constanza; Marcos, Ricard; Tauler, Albert; Yanes, Oscar; Agell, Neus; Kozma, Sara C.; Gentilella, Antonio; Thomas, George

Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53 Independent of Increased Ribosome Content 致癌性MYC诱导受损的核糖体生物发生检查点并稳定p53，而与核糖体含量增加无关

CANCER RESEARCH

IF16.6

2019-09-03

OAAI

Morcelle, Carmen; Menoyo, Sandra; Moron-Duran, Francisco D.; Tauler, Albert; Kozma, Sara C.; Thomas, George; Gentilella, Antonio

Mitochondrial Complex I Activity Is Required for Maximal Autophagy

CELL REPORTS

IF6.9

2018-08-01

OAAI

Thomas, Hala Elnakat; Zhang, Yu; Stefely, Jonathan A.; Veiga, Sonia R.; Thomas, George; Kozma, Sara C.; Mercer, Carol A.

Phenformin-Induced Mitochondrial Dysfunction Sensitizes Hepatocellular Carcinoma for Dual Inhibition of mTOR

CLINICAL CANCER RESEARCH

IF10.2

2018-07-31

OAAI

Veiga, Sonia R.; Ge, Xuemei; Mercer, Carol A.; Hernandez-Alvarez, Maria I.; Elnakat Thomas, Hala; Hernandez-Losa, Javier; Ramon y Cajal, Santiago; Zorzano, Antonio; Thomas, George; Kozma, Sara C.

Autogenous Control of 5′TOP mRNA Stability by 40S Ribosomes

MOLECULAR CELL

IF16.6

2017-07-01

OAAI

Gentilella, Antonio; Moron-Duran, Francisco D.; Fuentes, Pedro; Zweig-Rocha, Guilherme; Riano-Canalias, Ferran; Pelletier, Joffrey; Ruiz, Marta; Turon, Gemma; Castano, Julio; Tauler, Albert; Bueno, Clara; Menendez, Pablo; Kozma, Sara C.; Thomas, George

A Phase Ib Study of the Dual PI3K/mTOR Inhibitor Dactolisib (BEZ235) Combined with Everolimus in Patients with Advanced Solid Malignancies

TARGETED ONCOLOGY

IF4

2017-03-29

OAAI

Wise-Draper, Trisha M.; Moorthy, Ganesh; Salkeni, Mohamad A.; Karim, Nagla Abdel; Thomas, Hala Elnakat; Mercer, Carol A.; Beg, M. Shalaan; O'Gara, Sue; Olowokure, Olugbenga; Fathallah, Hassana; Kozma, Sara C.; Thomas, George; Rixe, Olivier; Desai, Pankaj; Morris, John C.

Targeting GMP synthesis reveals a hierarchy of p53-cell cycle checkpoints in c-Myc driven CRCs

EUROPEAN JOURNAL OF CANCER

IF7.1

2016-07-01

PREAI

Pelletier, J.; Riano-Canalias, F.; Salazar, R.; Villanueva, A.; Yanes, O.; Kozma, S.; Thomas, G.

S6K1 Phosphorylation of H2B Mediates EZH2 Trimethylation of H3: A Determinant of Early Adipogenesis

MOLECULAR CELL

IF16.6

2016-05-01

OAAI

Yi, Sang Ah; Um, Sung Hee; Lee, Jaecheol; Yoo, Ji Hee; Bang, So Young; Park, Eun Kyung; Lee, Min Gyu; Nam, Ki Hong; Jeon, Ye Ji; Park, Jong Woo; You, Jueng Soo; Lee, Sang-Jin; Bae, Gyu-Un; Rhie, Jong Won; Kozma, Sara C.; Thomas, George; Han, Jeung-Whan

S6K-STING interaction regulates cytosolic DNA-mediated activation of the transcription factor IRF3

NATURE IMMUNOLOGY

IF27.6

2016-04-04

OAAI

Wang, Fuan; Alain, Tommy; Szretter, Kristy J.; Stephenson, Kyle; Pol, Jonathan G.; Atherton, Matthew J.; Hoang, Huy-Dung; Fonseca, Bruno D.; Zakaria, Chadi; Chen, Lan; Rangwala, Zainab; Hesch, Adam; Chan, Eva Sin Yan; Tuinman, Carly; Suthar, Mehul S.; Jiang, Zhaozhao; Ashkar, Ali A.; Thomas, George; Kozma, Sara C.; Gale, Michael, Jr.; Fitzgerald, Katherine A.; Diamond, Michael S.; Mossman, Karen; Sonenberg, Nahum; Wan, Yonghong; Lichty, Brian D.

Effect of low doses of actinomycin D on neuroblastoma cell lines

MOLECULAR CANCER

IF33.9

2016-01-04

OAAI

Cortes, Constanza L.; Veiga, Sonia R.; Almacellas, Eugenia; Hernandez-Losa, Javier; Ferreres, Joan C.; Kozma, Sara C.; Ambrosio, Santiago; Thomas, George; Tauler, Albert

MYCN concurrence with SAHA-induced cell death in human neuroblastoma cells MYCN与SAHA诱导的人神经母细胞瘤细胞死亡的一致性

CELLULAR ONCOLOGY

IF4.8

2015-08-26

PREAI

Cortes, Constanza; Kozma, Sara C.; Tauler, Albert; Ambrosio, Santiago

c-Myc driven B cell lymphomas: role of the RPL5/RPL11/5S rRNA-MDM2 inhibitory complex (L5/L11/5S-MIC)

CANCER RESEARCH

IF16.6

2015-08-01

PREAI

Peddigari, Suresh; Mercer, Carol; Kozma, Sara; Thomas, George

Dual inhibition of mTOR in hepatocellular carcinoma: Autophagy friend or foe?

MOLECULAR CANCER THERAPEUTICS

IF5.5

2015-07-06

PREAI

Pereira Da Veiga, Sonia; Mercer, Carol; Ge Xuemei; Thomas, Hala Elnakat; Kozma, Sara; Thomas, George

S6K1 controls pancreatic β cell size independently of intrauterine growth restriction S6K1独立于子宫内生长受限控制胰腺 β 细胞大小

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2015-06-15

OAAI

Um, Sung Hee; Sticker-Jantscheff, Melanie; Chau, Gia Cac; Vintersten, Kristina; Mueller, Matthias; Gangloff, Yann-Gael; Adams, Ralf H.; Spetz, Jean-Francois; Elghazi, Lynda; Pfluger, Paul T.; Pende, Mario; Bernal-Mizrachi, Ernesto; Tauler, Albert; Tschoep, Matthias H.; Thomas, George; Kozma, Sara C.

研究方向