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Soo-Kyung Kim

California Institute of Technology

H指数:19

被引数:1,338

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Atomistic Mechanism Underlying the Regulation of the GPA1 G Protein Signaling Pathway Mediated by the Gibberellin A1 Phytohormone Binding to the GCR1 Plant G-Protein-Coupled Receptor

赤霉素A1植物激素与GCR1植物G蛋白偶联受体结合介导的GPA1 G蛋白信号通路调控的原子机制

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2025-05-190

PRE

Structure and Molecular Mechanism of Signaling for the Glucagon-like Peptide-1 Receptor Bound to Gs Protein and Exendin-P5 Biased Agonist

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2023-09-064

OA

Discovery and Binding Mechanism of Pyrazoloisoquinoline-Based Novel β-Arrestin Inverse Agonists of the Kappa-Opioid Receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-03-291

PRE

Predicted Three-Dimensional Structure of the GCR1 Putative GPCR in Arabidopsis thaliana and Its Binding to Abscisic Acid and Gibberellin A1

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2023-03-284

PRE

Synergic Effects in the Activation of the Sweet Receptor GPCR Heterodimer for Various Sweeteners Predicted Using Molecular Metadynamics Simulations

使用分子元动力学模拟预测的各种甜味剂在甜味受体GPCR异二聚体激活中的协同作用

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

IF6.2

2021-10-0614

OA

Predicted Structure of Fully Activated Tas1R3/1R3' Homodimer Bound to G Protein and Natural Sugars: Structural Insights into G Protein Activation by a Class C Sweet Taste Homodimer with Natural Sugars

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-09-2911

OA

Discovery of Novel Biased Opioid Receptor Ligands through Structure-Based Pharmacophore Virtual Screening and Experiment

IF3.4

2019-09-267

OAAI

Activation mechanism of the G protein-coupled sweet receptor heterodimer with sweeteners and allosteric agonists

G蛋白偶联甜味受体异二聚体与甜味剂和变构激动剂的激活机制

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-02-2271

OAAI

Antifreeze proteins govern the precipitation of trehalose in a freezing-avoiding insect at low temperature

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-05-2579

OAAI

Structure-Based Prediction of Subtype Selectivity of Histamine H3 Receptor Selective Antagonists in Clinical Trials

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2011-11-1639

OA

Predicted Structures and Dynamics for Agonists and Antagonists Bound to Serotonin 5-HT2B and 5-HT2C Receptors

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2011-02-0729

OAAI

Selective A3 adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2008-09-0143

OAAI

Distinct structural changes in a g protein-coupled receptor caused by different classes of agonist ligands

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2007-09-0151

OAAI

Rapid identification of functionally critical amino acids in a G protein-coupled receptor

IF32.1

2007-01-0750

PREAI

2-Triazole-substituted adenosines:: A new class of selective A3 adenosine receptor agonists, partial agonists, and antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-11-1584

OA

Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2006-04-1142

OAAI

Allosteric modulation of the adenosine family of receptors

MINI-REVIEWS IN MEDICINAL CHEMISTRY

IF3.3

2005-06-0163

OAAI

Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast -: Identification of second-site mutations that restore function to a coupling-deficient mutant M3 receptor

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2005-02-0132

OAAI

Exploring distal regions of the A3 adenosine receptor binding site:: sterically constrained N6-(2-phenylethyl)adenosine derivatives as potent ligands

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2004-05-0165

OAAI

Structure-activity relationships of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists

噻唑和噻二唑衍生物作为有效和选择性的人腺苷A3受体拮抗剂的构效关系

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2004-02-01139

OAAI