Frederick J. Livesey - Publications, H-index & Citations

Frederick J. Livesey

University of Cambridge

49H指数

163论文数

1.2W被引数

收录论文 54

发表时间

Synaptotoxic effects of extracellular tau are mediated by its microtubule-binding region 细胞外tau蛋白的突触毒性效应由其微管结合区介导

Acta Neuropathologica

IF9.3

2025-06-02

OAAI

Tomas Ondrejcak; Neng-Wei Hu; Emily Coode; Tom Campbell; Grant T. Corbett; Ivan Doykov; Kevin Mills; Dominic M. Walsh; Frederick J. Livesey; Michael J. Rowan; Igor Klyubin

APP antisense oligonucleotides are effective in rescuing mitochondrial phenotypes in human iPSC-derived trisomy 21 astrocytes APP反义寡核苷酸在拯救人iPSC来源的21三体星形胶质细胞的线粒体表型方面是有效的。

ALZHEIMERS & DEMENTIA

IF0

2025-01-29

OAAI

Thirumalai, S; Livesey, FJ; Patani, R; Hung, C

Clearance of beta-amyloid and tau aggregates is size dependent and altered by an inflammatory challenge Β-淀粉样蛋白和tau聚集体的清除是大小依赖性的，并因炎症挑战而改变

BRAIN COMMUNICATIONS

IF4.5

2024-12-14

OAAI

Fertan, Emre; Hung, Christy; Danial, John S. H.; Lam, Jeff Y. L.; Preman, Pranav; Albertini, Giulia; English, Elizabeth A.; Boeken, Dorothea; Livesey, Frederick J.; De Strooper, Bart; Patani, Rickie; Klenerman, David

Patient-derived tau and amyloid-β facilitate long-term depression in vivo: role of tumour necrosis factor-α and the integrated stress response

BRAIN COMMUNICATIONS

IF4.5

2024-09-27

OAAI

Hu, Neng-Wei; Ondrejcak, Tomas; Klyubin, Igor; Yang, Yin; Walsh, Dominic M.; Livesey, Frederick J.; Rowan, Michael J.

APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer's disease

BRAIN

IF11.7

2024-03-25

OAAI

Hung, Christy; Fertan, Emre; Livesey, Frederick J.; Klenerman, David; Patani, Rickie

Loss of CNTNAP2 Alters Human Cortical Excitatory Neuron Differentiation and Neural Network Development

BIOLOGICAL PSYCHIATRY

IF9

2023-11-01

OAAI

St George-Hyslop, Frances; Haneklaus, Moritz; Kivisild, Toomas; Livesey, Frederick J.

The role of contactin-associated protein-like 2 in neurodevelopmental disease and human cerebral cortex evolution

FRONTIERS IN MOLECULAR NEUROSCIENCE

IF3.8

2022-10-20

OAAI

St George-Hyslop, Frances; Kivisild, Toomas; Livesey, Frederick J.

Endolysosome and autophagy dysfunction in Alzheimer disease 阿尔茨海默病的内溶酶体和自噬功能障碍

AUTOPHAGY

IF14.3

2021-08-25

OAAI

Hung, Christy; Livesey, Frederick J.

SORL1 deficiency in human excitatory neurons causes APP-dependent defects in the endolysosome-autophagy network

CELL REPORTS

IF6.9

2021-06-01

OAAI

Hung, Christy; Tuck, Eleanor; Stubbs, Victoria; van der Lee, Sven J.; Aalfs, Cora; van Spaendonk, Resie; Scheltens, Philip; Hardy, John; Holstege, Henne; Livesey, Frederick J.

Tumour necrosis factor induces increased production of extracellular amyloid-β- and α-synuclein-containing aggregates by human Alzheimer's disease neurons

BRAIN COMMUNICATIONS

IF4.5

2020-09-15

OAAI

Whiten, Daniel R.; Brownjohn, Philip W.; Moore, Steven; De, Suman; Strano, Alessio; Zuo, Yukun; Haneklaus, Moritz; Klenerman, David; Livesey, Frederick J.

Variable Outcomes in Neural Differentiation of Human PSCs Arise from Intrinsic Differences in Developmental Signaling Pathways 人类psc神经分化的可变结果来自发育信号通路的内在差异

CELL REPORTS

IF6.9

2020-06-01

OAAI

Strano, Alessio; Tuck, Eleanor; Stubbs, Victoria E.; Livesey, Frederick J.

Mutations in thyroid hormone receptor α1 cause premature neurogenesis and progenitor cell depletion in human cortical development

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-10-18

OAAI

Krieger, Teresa G.; Moran, Carla M.; Frangini, Alberto; Visser, W. Edward; Schoenmakers, Erik; Muntoni, Francesco; Clark, Chris A.; Gadian, David; Chong, Wui K.; Kuczynski, Adam; Dattani, Mehul; Lyons, Greta; Efthymiadou, Alexandra; Varga-Khadem, Faraneh; Simons, Benjamin D.; Chatterjee, Krishna; Livesey, Frederick J.

Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia

CELL REPORTS

IF6.9

2019-01-01

128

OAAI

Paonessa, Francesco; Evans, Lewis D.; Solanki, Ravi; Larrieu, Delphine; Wray, Selina; Hardy, John; Jackson, Stephen P.; Livesey, Frederick J.

Altered γ-Secretase Processing of APP Disrupts Lysosome and Autophagosome Function in Monogenic Alzheimer's Disease

CELL REPORTS

IF6.9

2018-12-01

104

OAAI

Hung, Christy O. Y.; Livesey, Frederick J.

Guided self-organization and cortical plate formation in human brain organoids (vol 35, pg 659, 2017)

NATURE BIOTECHNOLOGY

IF41.7

2018-10-01

OAAI

Lancaster, Madeline A.; Corsini, Nina S.; Wolfinger, Simone; Gustafson, E. Hilary; Phillips, Alex W.; Burkard, Thomas R.; Otani, Tomoki; Livesey, Frederick J.; Knoblich, Juergen A.

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

STEM CELL REPORTS

IF5.1

2018-10-01

123

OAAI

Volpato, Viola; Smith, James; Sandor, Cynthia; Ried, Janina S.; Baud, Anna; Handel, Adam; Newey, Sarah E.; Wessely, Frank; Attar, Moustafa; Whiteley, Emma; Chintawar, Satyan; Verheyen, An; Barta, Thomas; Lako, Majlinda; Armstrong, Lyle; Muschet, Caroline; Artati, Anna; Cusulin, Carlo; Christensen, Klaus; Patsch, Christoph; Sharma, Eshita; Nicod, Jerome; Brownjohn, Philip; Stubbs, Victoria; Heywood, Wendy E.; Gissen, Paul; De Filippis, Roberta; Janssen, Katharina; Reinhardt, Peter; Adamski, Jerzy; Royaux, Ines; Peeters, Pieter J.; Terstappen, Georg C.; Graf, Martin; Livesey, Frederick J.; Akerman, Colin J.; Mills, Kevin; Bowden, Rory; Nicholson, George; Webber, Caleb; Cader, M. Zameel; Lakics, Viktor

Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes

CELL REPORTS

IF6.9

2018-07-01

OAAI

Miyamoto, Kei; Nguyen, Khoi T.; Allen, George E.; Jullien, Jerome; Kumar, Dinesh; Otani, Tomoki; Bradshaw, Charles R.; Livesey, Frederick J.; Kellis, Manolis; Gurdon, John B.

Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity

CELL REPORTS

IF6.9

2018-05-01

OAAI

Hu, Neng-Wei; Corbett, Grant T.; Moore, Steven; Klyubin, Igor; O'Malley, Tiernan T.; Walsh, Dominic M.; Livesey, Frederick J.; Rowan, Michael J.

Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia

STEM CELL REPORTS

IF5.1

2018-04-01

120

OAAI