未登录 An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer (vol 17, pg 638, 2018) Bhakta, Sunil; Crocker, Lisa M.; Chen, Yvonne; Hazen, Meredith; Schutten, Melissa M.; Li, Dongwei; Kuijl, Coenraad; Ohri, Rachana; Zhong, Fiona; Poon, Kirsten A.; Go, Mary Ann T.; Cheng, Eric; Piskol, Robert; Firestein, Ron; Fourie-O'Donohue, Aimee; Kozak, Katherine R.; Raab, Helga; Hongo, Jo-Anne; Sampath, Deepak; Dennis, Mark S.; Scheller, Richard H.; Polakis, Paul; Junutula, Jagath R. 分享 收藏
An Anti-GDNF Family Receptor Alpha 1 (GFRA1) Antibody-Drug Conjugate for the Treatment of Hormone Receptor-Positive Breast Cancer Bhakta, Sunil; Crocker, Lisa M.; Chen, Yvonne; Hazen, Meredith; Schutten, Melissa M.; Li, Dongwei; Kuijl, Coenraad; Ohri, Rachana; Zhong, Fiona; Poon, Kirsten A.; Go, Mary Ann T.; Cheng, Eric; Piskol, Robert; Firestein, Ron; Fourie-O'Donohue, Aimee; Kozak, Katherine R.; Raab, Helga; Hongo, Jo-Anne; Sampath, Deepak; Dennis, Mark S.; Scheller, Richard H.; Polakis, Paul; Junutula, Jagath R. 分享 收藏
High-Throughput Cysteine Scanning To Identify Stable Antibody Conjugation Sites for Maleimide- and Disulfide-Based Linkers Ohri, Rachana; Bhakta, Sunil; Fourie-O'Donohue, Aimee; dela Cruz-Chuh, Josefa; Tsai, Siao Ping; Cook, Ryan; Wei, Binqing; Ng, Carl; Wong, Athena W.; Bos, Aaron B.; Farahi, Farzam; Bhakta, Jiten; Pillow, Thomas H.; Raab, Helga; Vandlen, Richard; Polakis, Paul; Liu, Yichin; Erickson, Hans; Junutula, Jagath R.; Kozak, Katherine R. 分享 收藏
Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity Wei, BinQing; Gunzner-Toste, Janet; Yao, Hui; Wang, Tao; Wang, Jing; Xu, Zijin; Chen, Jinhua; Wai, John; Nonomiya, Jim; Tsai, Siao Ping; Chuh, Josefa; Kozak, Katherine R.; Liu, Yichin; Yu, Shang-Fan; Lau, Jeff; Li, Guangmin; Phillips, Gail D.; Leipold, Doug; Kamath, Amrita; Su, Dian; Xu, Keyang; Eigenbrot, Charles; Steinbacher, Stefan; Ohri, Rachana; Raab, Helga; Staben, Leanna R.; Zhao, Guiling; Flygare, John A.; Pillow, Thomas H.; Verma, Vishal; Masterson, Luke A.; Howard, Philip W.; Safina, Brian 分享 收藏
Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers Gregson, Stephen J.; Masterson, Luke A.; Wei, Binqing; Pillow, Thomas H.; Spencer, Susan D.; Kang, Gyoung-Dong; Yu, Shang -Fan; Raab, Helga; Lau, Jeffrey; Li, Guangmin; Phillips, Gail D. Lewis; Gunner-Toste, Janet; Safina, Brian S.; Ohri, Rachana; Darwish, Martine; Kozak, Katherine R.; dela Cruz-Chuh, Josefa; Poison, Andrew; Flygare, John A.; Howard, Philip W. 分享 收藏
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A Novel Anti-CD22 Anthracycline-Based Antibody-Drug Conjugate (ADC) That Overcomes Resistance to Auristatin-Based ADCs Yu, Shang-Fan; Zheng, Bing; Go, MaryAnn; Lau, Jeff; Spencer, Susan; Raab, Helga; Soriano, Robert; Jhunjhunwala, Suchit; Cohen, Robert; Caruso, Michele; Polakis, Paul; Flygare, John; Polson, Andrew G. 分享 收藏
Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for THIOMAB™ Drug Conjugates Sukumaran, Siddharth; Gadkar, Kapil; Zhang, Crystal; Bhakta, Sunil; Liu, Luna; Xu, Keyang; Raab, Helga; Yu, Shang-Fan; Mai, Elaine; Fourie-O'Donohue, Aimee; Kozak, Katherine R.; Ramanujan, Saroja; Junutula, Jagath R.; Lin, Kedan 分享 收藏
Site-Specific Trastuzumab Maytansinoid Antibody-Drug Conjugates with Improved Therapeutic Activity through Linker and Antibody Engineering Pillow, Thomas H.; Tien, Janet; Parsons-Reponte, Kathryn L.; Bhakta, Sunil; Li, Hao; Staben, Leanna R.; Li, Guangmin; Chuh, Josefa; Fourie-O'Donohue, Aimee; Darwish, Martine; Yip, Victor; Liu, Luna; Leipold, Douglas D.; Su, Dian; Wu, Elmer; Spencer, Susan D.; Shen, Ben-Quan; Xu, Keyang; Kozak, Katherine R.; Raab, Helga; Vandlen, Richard; Phillips, Gail D. Lewis; Scheller, Richard H.; Polakis, Paul; Sliwkowski, Mark X.; Flygare, John A.; Junutula, Jagath R. 分享 收藏
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Total Antibody Quantification for MMAE-Conjugated Antibody-Drug Conjugates: Impact of Assay Format and Reagents Kozak, Katherine R.; Tsai, Siao Ping; Fourie-O'Donohue, Aimee; Chuh, Josefa dela Cruz; Roth, Leslie; Cook, Ryan; Chan, Elton; Chan, Pamela; Darwish, Martine; Ohri, Rachana; Raab, Helga; Zhang, Crystal; Lin, Kedan; Wong, Wai Lee T. 分享 收藏
The Melanosomal Protein PMEL17 as a Target for Antibody Drug Conjugate Therapy in Melanoma Chen, Youjun; Chalouni, Cecile; Tan, Christine; Clark, Robyn; Venook, Rayna; Ohri, Rachana; Raab, Helga; Firestein, Ron; Mallet, William; Polakis, Paul 分享 收藏
Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates Shen, Ben-Quan; Xu, Keyang; Liu, Luna; Raab, Helga; Bhakta, Sunil; Kenrick, Margaret; Parsons-Reponte, Kathryn L.; Tien, Janet; Yu, Shang-Fan; Mai, Elaine; Li, Dongwei; Tibbitts, Jay; Baudys, Jakub; Saadi, Ola M.; Scales, Suzie J.; McDonald, Paul J.; Hass, Philip E.; Eigenbrot, Charles; Trung Nguyen; Solis, Willy A.; Fuji, Reina N.; Flagella, Kelly M.; Patel, Darshana; Spencer, Susan D.; Khawlil, Leslie A.; Ebens, Allen; Wong, Wai Lee; Vandlen, Richard; Kaur, Surinder; Sliwkowski, Mark X.; Scheller, Richard H.; Polakis, Paul; Junutula, Jagath R. 分享 收藏
Engineered Thio-Trastuzumab-DM1 Conjugate with an Improved Therapeutic Index to Target Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Junutula, Jagath R.; Flagella, Kelly M.; Graham, Richard A.; Parsons, Kathryn L.; Ha, Edward; Raab, Helga; Bhakta, Sunil; Nguyen, Trung; Dugger, Debra L.; Li, Guangmin; Mai, Elaine; Phillips, Gail D. Lewis; Hiraragi, Hajime; Fuji, Reina N.; Tibbitts, Jay; Vandlen, Richard; Spencer, Susan D.; Scheller, Richard H.; Polakis, Paul; Sliwkowski, Mark X. 分享 收藏
Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma Polson, A. G.; Williams, M.; Gray, A. M.; Fuji, R. N.; Poon, K. A.; McBride, J.; Raab, H.; Januario, T.; Go, M.; Lau, J.; Yu, S-F; Du, C.; Fuh, F.; Tan, C.; Wu, Y.; Liang, W-C; Prabhu, S.; Stephan, J-P; Hongo, J-A; Dere, R. C.; Deng, R.; Cullen, M.; de Tute, R.; Bennett, F.; Rawstron, A.; Jack, A.; Ebens, A. 分享 收藏
In vivo effects of targeting CD79b with antibodies and antibody-drug conjugates Zheng, Bing; Fuji, Reina N.; Elkins, Kristi; Yu, Shang-Fan; Fuh, Franklin K.; Chuh, Josefa; Tan, Christine; Hongo, Jo-Anne; Raab, Helga; Kozak, Katherine R.; Williams, Marna; McDorman, Elena; Eaton, Dan; Ebens, Allen; Polson, Andrew G. 分享 收藏
A Modular Platform for the Rapid Site-Specific Radiolabeling of Proteins with 18F Exemplified by Quantitative Positron Emission Tomography of Human Epidermal Growth Factor Receptor 2 Gill, Herman S.; Tinianow, Jeff N.; Ogasawara, Annie; Flores, Judith E.; Vanderbilt, Alexander N.; Raab, Helga; Scheer, Justin M.; Vandlen, Richard; Williains, Simon-P.; Marik, Jan 分享 收藏
Antibody-Drug Conjugates for the Treatment of Non-Hodgkin's Lymphoma: Target and Linker-Drug Selection Polson, Andrew G.; Calemine-Fenaux, Jill; Chan, Pamela; Chang, Wesley; Christensen, Erin; Clark, Suzanna; de Sauvage, Frederic J.; Eaton, Dan; Elkins, Kristi; Elliott, J. Michael; Frantz, Gretchen; Fuji, Reina N.; Gray, Alane; Harden, Kristin; Ingle, Gladys S.; Kljavin, Noelyn M.; Koeppen, Hartmut; Nelson, Christopher; Prabhu, Saileta; Raab, Helga; Ross, Sarajane; Stephan, Jean-Philippe; Scales, Suzie J.; Spencer, Susan D.; Vandlen, Richard; Wranik, Bernd; Yu, Shang-Fan; Zheng, Bing; Ebens, Allen 分享 收藏
Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index Junutula, Jagath R.; Raab, Helga; Clark, Suzanna; Bhakta, Sunil; Leipold, Douglas D.; Weir, Sylvia; Chen, Yvonne; Simpson, Michelle; Tsai, Siao Ping; Dennis, Mark S.; Lu, Yanmei; Meng, Y. Gloria; Ng, Carl; Yang, Jihong; Lee, Chien C.; Duenas, Eileen; Gorrell, Jeffrey; Katta, Viswanatham; Kim, Amy; McDorman, Kevin; Flagella, Kelly; Venook, Rayna; Ross, Sarajane; Spencer, Susan D.; Wong, Wai Lee; Lowman, Henry B.; Vandlen, Richard; Sliwkowski, Mark X.; Scheller, Richard H.; Polakis, Paul; Mallet, William 分享 收藏
Anti-CD22-MCC-DM1 and MC-MMAF conjugates: Impact of assay format on pharmacokinetic parameters determination Stephan, Jean-Philippe; Chan, Pamela; Lee, Chien; Nelson, Christopher; Elliott, James Michael; Bechtel, Charity; Raab, Helga; Xie, David; Akutagawa, Jon; Baudys, Jakub; Saad, Ola; Prabhu, Saileta; Wong, Wai Lee T.; Vandlen, Richard; Jacobson, Fred; Ebens, Allen 分享 收藏
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