未登录 AOC 1044 induces exon 44 skipping and restores dystrophin protein in preclinical models of Duchenne muscular dystrophy AOC 1044诱导外显子44的跳跃，并在杜氏肌营养不良症的临床前模型中恢复了抗肌萎缩蛋白的表达。 Etxaniz, Usue; Marks, Isaac; Albin, Tyler; Diaz, Matthew; Bhardwaj, Raghav; Anderson, Aaron; Tyaglo, Olecya; Hoang, Tiffany; Missinato, Maria Azzurra; Svensson, Kristoffer; Badillo, Ben; Kovach, Philip R.; Leung, Laura; Cochran, Michael; Kwon, Hae Won; Ahad Shah, Md Nur; Maruyama, Rika; Yokota, Toshifumi; Doppalapudi, Venkata R.; Darimont, Beatrice; Younis, Husam S.; Flanagan, W. Michael; Levin, Arthur A.; Huang, Hanhua; Karamanlidis, Georgios 分享 收藏
A Phase I Study of DLYE5953A, an Anti-LY6E Antibody Covalently Linked to Monomethyl Auristatin E, in Patients with Refractory Solid Tumors Tolaney, Sara M.; Do, Khanh T.; Eder, Joseph P.; LoRusso, Patricia M.; Weekes, Colin D.; Chandarlapaty, Sarat; Chang, Ching-Wei; Chen, Shang-Chiung; Nazzal, Denise; Schuth, Eva; Brunstein, Flavia; Carrasco-Triguero, Montserrat; Darbonne, Walter C.; Giltnane, Jennifer M.; Flanagan, William M.; Commerford, S. Renee; Ungewickell, Alexander; Shapiro, Geoffrey I.; Modi, Shanu 分享 收藏
Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma Sandhu, Shahneen; McNeil, Catriona M.; LoRusso, Patricia; Patel, Manish R.; Kabbarah, Omar; Li, Chunze; Sanabria, Sandra; Flanagan, W. Michael; Yeh, Ru-Fang; Brunstein, Flavia; Nazzal, Denise; Hicks, Rodney; Lemahieu, Vanessa; Meng, Raymond; Hamid, Omid; Infante, Jeffrey R. 分享 收藏
Modeling the Kinetics of Lipid-Nanoparticle-Mediated Delivery of Multiple siRNAs to Evaluate the Effect on Competition for Ago2 Mihaila, Radu; Ruhela, Dipali; Galinski, Beverly; Card, Ananda; Cancilla, Mark; Shadel, Timothy; Kang, Jing; Tep, Samnang; Wei, Jie; Haas, R. Matthew; Caldwell, Jeremy; Flanagan, W. Michael; Kuklin, Nelly; Cherkaev, Elena; Ason, Brandon 分享 收藏
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Targeting MUC16 with the THIOMAB™-drug conjugate DMUC4064A in patients with platinum-resistant ovarian cancer: a Phase I escalation study Liu, Joyce F.; Moore, Kathleen N.; Wang, Judy S.; Patel, Manish; Birrer, Michael J.; Hamilton, Erika; Barroilhet, Lisa; Flanagan, William M.; Wang, Yulei; Garg, Amit; Lu, Xuyang; Vaze, Anjali; Amin, Dilip; Leipold, Doug; Commerford, S. Renee; Humke, Eric W.; Burris, Harold A. 分享 收藏
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Alzheimer's and other dementias in Canada, 2011 to 2031: a microsimulation Population Health Modeling (POHEM) study of projected prevalence, health burden, health services, and caregiving use Manuel, Douglas G.; Garner, Rochelle; Fines, Philippe; Bancej, Christina; Flanagan, William; Tu, Karen; Reimer, Kim; Chambers, Larry W.; Bernier, Julie 分享 收藏
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High-Throughput Chemical Modification of Oligonucleotides for Systematic Structure-Activity Relationship Evaluation Zewge, Daniel; Gosselin, Francis; Kenski, Denise M.; Li, Jenny; Jadhav, Vasant; Yuan, Yu; Nerurkar, Sandhya S.; Tellers, David M.; Flanagan, W. Michael; Davies, Ian W. 分享 收藏
Rescue of Mtp siRNA-induced hepatic steatosis by DGAT2 siRNA silencing Tep, Samnang; Mihaila, Radu; Freeman, Alexander; Pickering, Victoria; Huyhn, Felicia; Tadin-Strapps, Marija; Stracks, Allison; Hubbard, Brian; Caldwell, Jeremy; Flanagan, W. Michael; Kuklin, Nelly A.; Ason, Brandon 分享 收藏
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RNA-Induced Silencing Complex-Bound Small Interfering RNA Is a Determinant of RNA Interference-Mediated Gene Silencing in Mice Wei, Jie; Jones, Jeffrey; Kang, Jing; Card, Ananda; Krimm, Michael; Hancock, Paula; Pei, Yi; Ason, Brandon; Payson, Elmer; Dubinina, Natalya; Cancilla, Mark; Stroh, Mark; Burchard, Julja; Sachs, Alan B.; Hochman, Jerome H.; Flanagan, W. Michael; Kuklin, Nelly A. 分享 收藏
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