未登录High resolution imaging spectrometry using dispersion shearing interferometer with Amici prisms
Huang, Huitong; Li, Liansheng; Yang, Yu; Xing, Xiaoqun; Meng, Xin; Xu, Yixuan; Liu, Yixuan; Wu, Wenxuan; Zhu, Haibo; Zong, Yi; Li, Jianxin .png)
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收藏分享 收藏 Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRASG12C Inhibitor ARS-2102Yang, Xiaogen; Li, Zhiwen; Xu, Wenwen; Zhu, Guanming; Feng, Xiantong; Zhang, Jun; Zhao, Hongbin; Chen, Yuyin; Kong, Jianshe; Mai, Wanping; Li, Lian-Sheng; Pippel, Daniel J.; Ren, Pingda; Deng, Xiaohu 分享 收藏 分享 收藏 分享 收藏 Contribution of structural accessibility to the cooperative relationship of TF-lncRNA in myopiaWang, Hong; Li, Jing; Wang, Siyu; Lu, Xiaoyan; Zhang, Guosi; Zhuang, Youyuan; Li, Liansheng; Wang, Wencan; Lin, Peng; Chen, Chong; Wang, Hao; Chen, Qi; Jiang, Yongshuai; Qu, Jia; Xu, Liangde 分享 收藏 Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemiaKlossowski, Szymon; Miao, Hongzhi; Kempinska, Katarzyna; Wu, Tao; Purohit, Trupta; Kim, EunGi; Linhares, Brian M.; Chen, Dong; Jih, Gloria; Perkey, Eric; Huang, Huang; He, Miao; Wen, Bo; Wang, Yi; Yu, Ke; Lee, Stanley Chun-Wei; Danet-Desnoyers, Gwenn; Trotman, Winifred; Kandarpa, Malathi; Cotton, Anitria; Abdel-Wahab, Omar; Lei, Hongwei; Dou, Yali; Guzman, Monica; Peterson, Luke; Gruber, Tanja; Choi, Sarah; Sun, Duxin; Ren, Pingda; Li, Lian-Sheng; Liu, Yi; Burrows, Francis; Maillard, Ivan; Cierpicki, Tomasz; Grembecka, Jolanta 分享 收藏 Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancerMolina-Arcas, Miriam; Moore, Christopher; Rana, Sareena; van Maldegem, Febe; Mugarza, Edurne; Romero-Clavijo, Pablo; Herbert, Eleanor; Horswell, Stuart; Li, Lian-Sheng; Janes, Matthew R.; Hancock, David C.; Downward, Julian 分享 收藏 KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination with PI3K InhibitionMisale, Sandra; Fatherree, Jackson P.; Cortez, Eliane; Li, Chendi; Bilton, Samantha; Timonina, Daria; Myers, David T.; Lee, Dana; Gomez-Caraballo, Maria; Greenberg, Max; Nangia, Varuna; Greninger, Patricia; Egan, Regina K.; McClanaghan, Joseph; Stein, Giovanna T.; Murchie, Ellen; Zarrinkar, Patrick P.; Janes, Matthew R.; Li, Lian-Sheng; Liu, Yi; Hata, Aaron N.; Benes, Cyril H. 分享 收藏 Discovery of novel covalent KRASG12C inhibitors that display high potency and selectivity in vitro and in vivoLi, Liansheng; Janes, Matthew R.; Zhang, Jingchuan; Hansen, Rasmus; Peters, Ulf; Guo, Xin; Chen, Yuching; Babbar, Anjali; Firdaus, Sarah J.; Feng, Jun; Chen, Jeffrey H.; Li, Shuangwei; Li, Shisheng; Thach, Carol; Liu, Yuan; Zarieh, Ata; Kucharski, Jeff M.; Wu, Tao; Yu, Ke; Wang, Yi; Yao, Yvonne; Deng, Xiaohu; Zarrinkar, Patrick P.; Dhanak, Dashyant; Lorenzi, Matthew V.; Hu-Lowe, Dana; Ren, Pingda; Liu, Yi 分享 收藏 11q13 amplification selects for sensitivity to the ERK inhibitor KO-947 in squamous cell carcinomasBurrows, Francis J.; Kessler, Linda; Wu, Tao; Gao, Xin; Chen, Jeffrey; Hansen, Rasmus; Li, Shuangwei; Thach, Carol; Li, Shisheng; Yu, Ke; Kucharski, Jeff; Peters, Ulf; Feng, Jun; Wang, Yi; Yao, Yvonne; Zarieh, Ata; Janes, Matt; Zhang, Jingchuan; Li, Liansheng; Hu-Lowe, Dana; Ren, Pingda; Liu, Yi 分享 收藏 Drugging an undruggable pocket: The biochemical mechanism of covalent KRASG12C inhibitorsHansen, Rasmus; Peters, Ulf; Babbar, Anjali; Chen, Yuching; Feng, Jun; Janes, Matthew R.; Li, Liansheng; Ren, Pingda; Liu, Yi; Zarrinkar, Patrick P. 分享 收藏 The reactivity-driven biochemical mechanism of covalent KRASG12C inhibitorsHansen, Rasmus; Peters, Uif; Babbar, Anjali; Chen, Yuching; Feng, Jun; Janes, Matthew R.; Li, Lian-Sheng; Ren, Pingda; Liu, Yi; Zarrinkar, Patrick P. 分享 收藏 Regioselective Functionalization of 4-Methyl-1H-indole for Scalable Synthesis of 2-Cyano-5-formyl-4-methyl-1H-indoleZhang, Jun; Hu, Yun; Wang, Haiyu; Guo, Aixin; Kong, Jianshe; Ma, Rujian; Wu, Tao; Wang, Yi; Li, Lian-Sheng; Mai, Wanping; Ren, Pingda; Deng, Xiaohu 分享 收藏 A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemias and NPM1/DNMT3A-mutant AMLBurrows, Francis; Wu, Tao; Kessler, Linda; Li, Shuangwei; Zhang, Jingchuan; Zarrinkar, Patrick; Li, Liansheng; Cierpicki, Tomasz; Grembecka, Jolanta; Ren, Pingda; Liu, Yi 分享 收藏 KO-947, a potent ERK inhibitor with robust preclinical single agent activity in MAPK pathway dysregulated tumorsBurrows, Francis; Kessler, Linda; Chen, Jeffrey; Gao, Xin; Hansen, Rasmus; Li, Shuangwei; Thach, Carol; Darjania, Levan; Yao, Yvonne; Wang, Yi; Zarieh, Ata; Yu, Ke; Wu, Tao; Zhang, Jingchuan; Hu-Lowe, Dana; Li, Liansheng; Ren, Pingda; Liu, Yi 分享 收藏 A novel small molecule menin-MLL inhibitor for potential treatment of MLL-rearranged leukemiasWu, Tao; Kessler, Linda; Li, Shuangwei; Purohit, Trupta; Li, Shisheng; Miao, Hongzhi; Linhares, Brian; Hansen, Rasmus; Kucharski, Jeff; Wang, Yi; Yu, Ke; Kempinska, Katarzyna; Ely, Tess; Klossowski, Szymon; Zarieh, Ata; Peters, Ulf; Feng, Jun; Yao, Yvonne; Liu, Yuan; Wen, Bo; Burrows, Francis; Sun, Duxin; Zhang, Jingchuan; Darjania, Levan; Hu-Lowe, Dana; Zarrinkar, Patrick; Li, Liansheng; Cierpicki, Tomasz; Grembecka, Jolanta; Ren, Pingda; Liu, Yi 分享 收藏 Identification of cancer risk lncRNAs and cancer risk pathways regulated by cancer risk lncRNAs based on genome sequencing data in human cancersLi, Yiran; Li, Wan; Liang, Binhua; Li, Liansheng; Wang, Li; Huang, Hao; Guo, Shanshan; Wang, Yahui; He, Yuehan; Chen, Lina; He, Weiming 分享 收藏 分享 收藏 Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State靶向无活性状态的小分子选择性抑制致癌KRAS输出Patricelli, Matthew P.; Janes, Matthew R.; Li, Lian-Sheng; Hansen, Rasmus; Peters, Ulf; Kessler, Linda V.; Chen, Yuching; Kucharski, Jeff M.; Feng, Jun; Ely, Tess; Chen, Jeffrey H.; Firdaus, Sarah J.; Babbar, Anjali; Ren, Pingda; Liu, Yi 分享 收藏 
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