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收藏Trypsin in pancreatitis: The culprit, a mediator, or epiphenomenon?
Gukovskaya, Anna S.; Lerch, Markus M.; Mayerle, Julia; Sendler, Matthias; Ji, Baoan; Saluja, Ashok K.; Gorelick, Fred S.; Gukovsky, Ilya
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收藏The safety and efficacy outcomes of Minnelide given alone or in combination with paclitaxel in advanced gastric cancer: A phase I trial米奈利特单独或联合紫杉醇治疗晚期胃癌的安全性和有效性: I期试验
Lim, Sung Hee; Saluja, Ashok; Vickers, Selwyn; Hong, Jung Yong; Kim, Seung Tae; Lavania, Shweta; Pandey, Somnath; Gupta, Vineet K.; Velagapudi, Mohana R.; Lee, Jeeyun
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收藏Minnelide suppresses GVHD and enhances survival while maintaining GVT responses
Copsel, Sabrina N.; Garrido, Vanessa T.; Barreras, Henry; Bader, Cameron S.; Pfeiffer, Brent; Mateo-Victoriano, Beatriz; Wolf, Dietlinde; Gallardo, Miguel; Paczesny, Sophie; Komanduri, Krishna V.; Benjamin, Cara L.; Villarino, Alejandro V.; Saluja, Ashok K.; Levy, Robert B.
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收藏Phase II open label trial of Minnelide™ in patients with chemotherapy refractory metastatic pancreatic cancer
Propper, David; Borazanci, Erkut; O'Dwyer, Peter J.; Von Hoff, Daniel; Hartlebury, Joseph; Antal, Corina E.; Evan, Gerard I.; Han, HaiYong; Downes, Michael; Evans, Ronald; Rabinowitz, Joshua; Petricoin, Emmanuel; Saluja, Ashok; Velagapudi, Mohana; Patel, Hitendra
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收藏Identification of novel early pancreatic cancer biomarkers KIF5B and SFRP2 from first contact interactions in the tumor microenvironment从肿瘤微环境中首次接触相互作用鉴定新型早期胰腺癌生物标志物KIF5B和SFRP2
Jacob, Harrys Kishore Charles; Signorelli, Rossana; Richard, John Lalith Charles; Kashuv, Tyler; Lavania, Shweta; Middleton, Ashley; Gomez, Beatriz Aguilar; Ferrantella, Anthony; Amirian, Haleh; Tao, Junyi; Ergonul, Ayse Burcu; Boone, Melinda Minucci; Hadisurya, Marco; Tao, Weiguo Andy; Iliuk, Anton; Kashyap, Manoj Kumar; Garcia-Buitrago, Monica; Dawra, Rajinder; Saluja, Ashok Kumar
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收藏Minnelide synergizes with conventional chemotherapy by targeting both cancer and associated stroma components in pancreatic cancer
Modi, Shrey; Giri, Bhuwan; Gupta, Vineet K.; Lavania, Shweta; Sethi, Vrishketan; Sharma, Nikita S.; Pandey, Somnath; Vickers, Selwyn; Dudeja, Vikas; Saluja, Ashok K.
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收藏Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models
Bava, Ejas Palathingal; George, John; Tarique, Mohammad; Iyer, Srikanth; Sahay, Preeti; Aguilar, Beatriz Gomez; Edwards, Dujon B.; Giri, Bhuwan; Sethi, Vrishketan; Jain, Tejeshwar; Sharma, Prateek; Vaish, Utpreksha; Jacob, Harrys K. C.; Ferrantella, Anthony; Maynard, Craig L.; Saluja, Ashok K.; Dawra, Rajinder K.; Dudeja, Vikas
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收藏Hsp70 modulates immune response in pancreatic cancer through dendritic cells
Giri, Bhuwan; Sharma, Prateek; Jain, Tejeshwar; Ferrantella, Anthony; Vaish, Utpreksha; Mehra, Siddharth; Garg, Bharti; Iyer, Srikanth; Sethi, Vrishketan; Malchiodi, Zoe; Signorelli, Rossana; Jacob, Harrys K. C.; George, John; Sahay, Preeti; Bava, Ejas P.; Dawra, Rajinder; Ramakrishnan, Sundaram; Saluja, Ashok; Dudeja, Vikas
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收藏Hypoxia-Driven Oncometabolite L-2HG Maintains Sternness-Differentiation Balance and Facilitates Immune Evasion in Pancreatic Cancer缺氧驱动的骨代谢产物L-2HG可维持干细胞分化平衡并促进胰腺癌的免疫逃避
Gupta, Vineet K.; Sharma, Nikita S.; Durden, Brittany; Garrido, Vanessa T.; Kesh, Kousik; Edwards, Dujon; Wang, Dezhen; Myer, Ciara; Mateo-Victoriano, Beatriz; Kollala, Sai Sundeep; Ban, Yuguang; Gao, Zhen; Bhattacharya, Sanjoy K.; Saluja, Ashok; Singh, Pankaj K.; Banerjee, Sulagna
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收藏Stroma secreted IL6 selects for stem-like population and alters pancreatic tumor microenvironment by reprogramming metabolic pathways基质分泌的IL6选择干细胞样群体并通过重编程代谢途径改变胰腺肿瘤微环境
Kesh, Kousik; Garrido, Vanessa T.; Dosch, Austin; Durden, Brittany; Gupta, Vineet K.; Sharma, Nikita S.; Lyle, Michael; Nagathihalli, Nagaraj; Merchant, Nipun; Saluja, Ashok; Banerjee, Sulagna
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收藏Targeting tumor-intrinsic metabolic node in pancreatic cancer causes tumor regression, remodels extracellular matrix, and sensitizes to anti-PD1 therapy
Sharma, Nikita S.; Gupta, Vineet K.; Garrido, Vanessa; Hadad, Roey; Durden, Brittany; Kesh, Kousik; Ferrantella, Anthony; Giri, Bhuwan; Dudeja, Vikas; Saluja, Ashok; Banerjee, Sulagna
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收藏Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy靶向肿瘤-固有的己糖胺生物合成使胰腺癌对anti-PD1治疗敏感
Sharma, Nikita S.; Gupta, Vineet K.; Garrido, Vanessa T.; Hadad, Roey; Durden, Brittany C.; Kesh, Kousik; Giri, Bhuwan; Ferrantella, Anthony; Dudeja, Vikas; Saluja, Ashok; Banerjee, Sulagna
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