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A

Andrew T. Hughes

Agilent Technologies
H指数:21
被引数:1,327

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Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria
HUMAN MOLECULAR GENETICS
IF3.2
2019-10-1014
OAAI
Hughes, Juliette H.; Liu, Ke; Plagge, Antonius; Wilson, Peter J. M.; Sutherland, Hazel; Norman, Brendan P.; Hughes, Andrew T.; Keenan, Craig M.; Milan, Anna M.; Sakai, Takao; Ranganath, Lakshminarayan R.; Gallagher, James A.; Bou-Gharios, George
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging

使用质谱成像评估尼西酮诱导的高酪氨酸血症对链蛋白尿小鼠模型脑组织中单胺神经递质的影响

METABOLOMICS
IF3.3
2019-04-2926
OAAI
Davison, Andrew S.; Strittmatter, N.; Sutherland, H.; Hughes, A. T.; Hughes, J.; Bou-Gharios, G.; Milan, A. M.; Goodwin, R. J. A.; Ranganath, L. R.; Gallagher, J. A.
Nitisinone arrests ochronosis and decreases rate of progression of Alkaptonuria: Evaluation of the effect of nitisinone in the United Kingdom National Alkaptonuria Centre
MOLECULAR GENETICS AND METABOLISM
IF3.5
2018-09-0175
OAAI
Ranganath, L. R.; Khedr, M.; Milan, A. M.; Davison, A. S.; Hughes, A. T.; Usher, J. L.; Taylor, S.; Loftus, N.; Daroszewska, A.; West, E.; Jones, A.; Briggs, M.; Fisher, M.; McCormick, M.; Judd, S.; Vinjamuri, S.; Griffin, R.; Psarelli, E. E.; Cox, T. F.; Sireau, N.; Dillon, J. P.; Devine, J. M.; Hughes, G.; Harrold, J.; Barton, G. J.; Jarvis, J. C.; Gallagher, J. A.
Suitability Of Nitisinone In Alkaptonuria 1 (SONIA 1): an international, multicentre, randomised, open-label, no-treatment controlled, parallel-group, dose-response study to investigate the effect of once daily nitisinone on 24-h urinary homogentisic acid excretion in patients with alkaptonuria after 4 weeks of treatment
ANNALS OF THE RHEUMATIC DISEASES
IF20.6
2016-02-01105
OAAI
Ranganath, Lakshminarayan R.; Milan, Anna M.; Hughes, Andrew T.; Dutton, John J.; Fitzgerald, Richard; Briggs, Michael C.; Bygott, Helen; Psarelli, Eftychia E.; Cox, Trevor F.; Gallagher, James A.; Jarvis, Jonathan C.; van Kan, Christa; Hall, Anthony K.; Laan, Dinny; Olsson, Birgitta; Szamosi, Johan; Rudebeck, Mattias; Kullenberg, Torbjorn; Cronlund, Arvid; Svensson, Lennart; Junestrand, Carin; Ayoob, Hana; Timmis, Oliver G.; Sireau, Nicolas; Le Quan Sang, Kim-Hanh; Genovese, Federica; Braconi, Daniela; Santucci, Annalisa; Nemethova, Martina; Zatkova, Andrea; McCaffrey, Judith; Christensen, Peter; Ross, Gordon; Imrich, Richard; Rovensky, Jozef

研究方向

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A
Anna M. Milan
H 指数:25论文数:93被引数:1,826
L
L. Ranganath
H 指数:40论文数:375被引数:5,476
A
Andrew Davison
H 指数:25论文数:138被引数:2,749
G
George Bou–Gharios
H 指数:49论文数:269被引数:8,619
B
Brendan P. Norman
H 指数:14论文数:65被引数:918
H
Hazel Sutherland
H 指数:24论文数:70被引数:1,491
M
Milad Khedr
H 指数:16论文数:52被引数:684
J
James A. Gallagher
H 指数:39论文数:198被引数:4,030
J
Juliette H. Hughes
H 指数:9论文数:25被引数:359
R
Richard Imrich
H 指数:32论文数:159被引数:3,282