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J

Juliette H. Hughes

University of Liverpool
H指数:9
被引数:359

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Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria

特异性敲除肾脏同戊二烯二酸1,2-二氧化酶揭示酪氨酸和同戊二烯二酸的局部代谢在黑酸尿症中可忽略不计

Human Molecular Genetics
IF3.2
2026-05-250
OA
Dominic A Rutland; Brendan P Norman; Juliette H Hughes; Peter J M Wilson; Hazel Sutherland; Rebecca L W Brown; James A Gallagher; Lakshminarayan R Ranganath; George Bou-Gharios
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria
HUMAN MOLECULAR GENETICS
IF3.2
2019-10-1014
OAAI
Hughes, Juliette H.; Liu, Ke; Plagge, Antonius; Wilson, Peter J. M.; Sutherland, Hazel; Norman, Brendan P.; Hughes, Andrew T.; Keenan, Craig M.; Milan, Anna M.; Sakai, Takao; Ranganath, Lakshminarayan R.; Gallagher, James A.; Bou-Gharios, George
Assessing the effect of nitisinone induced hypertyrosinaemia on monoamine neurotransmitters in brain tissue from a murine model of alkaptonuria using mass spectrometry imaging

使用质谱成像评估尼西酮诱导的高酪氨酸血症对链蛋白尿小鼠模型脑组织中单胺神经递质的影响

METABOLOMICS
IF3.3
2019-04-2926
OAAI
Davison, Andrew S.; Strittmatter, N.; Sutherland, H.; Hughes, A. T.; Hughes, J.; Bou-Gharios, G.; Milan, A. M.; Goodwin, R. J. A.; Ranganath, L. R.; Gallagher, J. A.

研究方向

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G
George Bou–Gharios
H 指数:49论文数:269被引数:8,614
H
Hazel Sutherland
H 指数:24论文数:70被引数:1,489
L
L. Ranganath
H 指数:40论文数:375被引数:5,475
A
Anna M. Milan
H 指数:25论文数:93被引数:1,826
A
Andrew T. Hughes
H 指数:21论文数:68被引数:1,327
P
Peter J. Wilson
H 指数:43论文数:140被引数:1.9万
B
Brendan P. Norman
H 指数:14论文数:65被引数:918
A
Andrew Davison
H 指数:25论文数:138被引数:2,748
J
James A. Gallagher
H 指数:39论文数:198被引数:4,030
J
Jonathan C. Jarvis
H 指数:35论文数:196被引数:4,493