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PD1 blockade improves survival and CD8+ cytotoxic capacity, without increasing inflammation, during normal microbial experience in old mice 在老年小鼠的正常微生物经历期间，PD1阻断可改善存活率和CD8细胞毒性能力，而不会增加炎症 Dahlquist, Korbyn J. V.; Huggins, Matthew A.; Yousefzadeh, Matthew J.; Soto-Palma, Carolina; Cholensky, Stephanie H.; Pierson, Mark; Smith, Declan M.; Hamilton, Sara E.; Camell, Christina D. 分享 收藏
Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue sepsis 脂肪组织脓毒症中b细胞的年龄相关积累促进巨噬细胞炎症并抑制脂肪分解 Carey, Anna; Nguyen, Katie; Kandikonda, Pranathi; Kruglov, Victor; Bradley, Claire; Dahlquist, Korbyn J. V.; Cholensky, Stephanie; Swanson, Whitney; Badovinac, Vladimir P.; Griffith, Thomas S.; Camel, Christina D. 分享 收藏
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PROTAC Linkerology Leads to an Optimized Bivalent Chemical Degrader of Polycomb Repressive Complex 2 (PRC2) Components Bashore, Frances M.; Foley, Caroline A.; Ong, Han Wee; Rectenwald, Justin M.; Hanley, Ronan P.; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Mills, Christine A.; Pearce, Kenneth H.; Herring, Laura E.; Kireev, Dmitri; Frye, Stephen, V; James, Lindsey I. 分享 收藏
Reprogramming CBX8-PRC1 function with a positive allosteric modulator Suh, Junghyun L.; Bsteh, Daniel; Hart, Bryce; Si, Yibo; Weaver, Tyler M.; Pribitzer, Carina; Lau, Roy; Soni, Shivani; Ogana, Heather; Rectenwald, Justin M.; Norris, Jacqueline L.; Cholensky, Stephanie H.; Sagum, Cari; Umana, Jessica D.; Li, Dongxu; Hardy, Brian; Bedford, Mark T.; Mumenthaler, Shannon M.; Lenz, Heinz-Josef; Kim, Yong-Mi; Wang, Gang Greg; Pearce, Ken H.; James, Lindsey, I; Kireev, Dmitri B.; Musselman, Catherine A.; Frye, Stephen, V; Bell, Oliver 分享 收藏
Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins Lamb, Kelsey N.; Dishman, Sarah N.; Waybright, Jarod M.; Engelberg, Isabelle A.; Rectenwald, Justin M.; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Pearce, Kenneth H.; James, Lindsey, I; Frye, Stephen, V 分享 收藏
A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex Waybright, Jarod M.; Clinkscales, Sarah E.; Barnash, Kimberly D.; Budziszewski, Gabrielle R.; Rectenwald, Justin M.; Chiarella, Anna M.; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Pearce, Kenneth H.; Herring, Laura E.; McGinty, Robert K.; Hathaway, Nathaniel A.; James, Lindsey, I 分享 收藏
Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1) Engelberg, Isabelle A.; Liu, Jiuyang; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Ottavi, Samantha A.; Frye, Stephen, V; Kutateladze, Tatiana G.; James, Lindsey, I 分享 收藏
Discovery and Characterization of Peptide Inhibitors for Calcium and Integrin Binding Protein 1 Puhl, Ana C.; Bogart, Jonathan W.; Haberman, Victoria A.; Larson, Jacob E.; Godoy, Andre S.; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Leisner, Tina M.; Frye, Stephen, V; Parise, Leslie, V; Bowers, Albert A.; Pearce, Kenneth H. 分享 收藏
Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins Rectenwald, Justin M.; Guduru, Shiva Krishna Reddy; Dang, Zhao; Collins, Leonard B.; Liao, Yi-En; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Kaufmann, Kyle W.; Hammond, Scott M.; Kireev, Dmitri B.; Frye, Stephen, V; Pearce, Kenneth H. 分享 收藏
Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader 用EED靶向的二价化学降解剂降解Polycomb抑制复合物2 Potjewyd, Frances; Turner, Anne-Marie W.; Beri, Joshua; Rectenwald, Justin M.; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Margolis, David M.; Pearce, Kenneth H.; Herring, Laura E.; James, Lindsey I. 分享 收藏
Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7 Lamb, Kelsey N.; Bsteh, Daniel; Dishman, Sarah N.; Moussa, Hagar F.; Fan, Huitao; Stuckey, Jacob I.; Norris, Jacqueline L.; Cholensky, Stephanie H.; Li, Dongxu; Wang, Jingkui; Sagum, Cari; Stanton, Benjamin Z.; Bedford, Mark T.; Pearce, Kenneth H.; Kenakin, Terry P.; Kireev, Dmitri B.; Wang, Gang Greg; James, Lindsey I.; Bell, Oliver; Frye, Stephen V. 分享 收藏
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 (vol 12, pg 180, 2016) Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Brown, Peter J.; TBedford, Mark; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
Structure-Activity Relationships and Kinetic Studies of Peptidic Antagonists of CBX Chromodomains Stuckey, Jacob I.; Simpson, Catherine; Norris-Drouin, Jacqueline L.; Cholensky, Stephanie H.; Lee, Junghyun; Pasca, Ryan; Cheng, Nancy; Dickson, Bradley M.; Pearce, Kenneth H.; Frye, Stephen V.; James, Lindsey I. 分享 收藏
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A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Browne, Peter J.; Bedford, Mark T.; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
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