Paul W. Finn - Publications, H-index & Citations

Paul W. Finn

mrc national institute for medical research

24H指数

94论文数

2.7K被引数

收录论文 23

发表时间

Novel antimicrobial 3-phenyl-4-phenoxypyrazole derivatives target cell wall lipid intermediates with low mammalian cytotoxicity 新型抗菌3-苯基-4-苯氧基吡唑衍生物靶向细胞壁脂质中间体，且对哺乳动物细胞毒性低

Scientific Reports

IF3.9

2025-10-13

OAAI

Blanca Fernandez-Ciruelos; Marco Albanese; Femke Taverne; Paul W. Finn; Jerry M. Wells

Repurposing Hsp90 inhibitors as antimicrobials targeting two-component systems identifies compounds leading to loss of bacterial membrane integrity

MICROBIOLOGY SPECTRUM

IF3.8

2024-08-06

OAAI

Fernandez-Ciruelos, Blanca; Albanese, Marco; Adhav, Anmol; Solomin, Vitalii; Ritchie-Martinez, Arabela; Taverne, Femke; Velikova, Nadya; Jirgensons, Aigars; Marina, Alberto; Finn, Paul W.; Wells, Jerry M.

Ligity: A Non-Superpositional, Knowledge-Based Approach to Virtual Screening

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2019-05-22

OAAI

Ebejer, Jean-Paul; Finn, Paul W.; Wong, Wing Ki; Deane, Charlotte M.; Morris, Garrett M.

N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2018-01-23

OAAI

Charlton, Michael H.; Aleksis, Rihards; Saint-Leger, Adelaide; Gupta, Arya; Loza, Einars; Ribas de Pouplana, Lluis; Kaula, Ilze; Gustina, Daina; Madre, Marina; Lola, Daina; Jaudzems, Kristaps; Edmund, Grace; Randall, Christopher P.; Kime, Louise; O'Neill, Alex J.; Goessens, Wil; Jirgensons, Aigars; Finn, Paul W.

Structure-guided selection of specificity determining positions in the human Kinome 结构指导的人类Kinome中特异性确定位置的选择

BMC GENOMICS

IF3.7

2016-08-18

OAAI

Moll, Mark; Finn, Paul W.; Kavraki, Lydia E.

Are the physicochemical properties of antibacterial compounds really different from other drugs?

JOURNAL OF CHEMINFORMATICS

IF5.7

2016-06-03

OAAI

Ebejer, Jean-Paul; Charlton, Michael H.; Finn, Paul W.

Putative histidine kinase inhibitors with antibacterial effect against multi-drug resistant clinical isolates identified by in vitro and in silico screens

SCIENTIFIC REPORTS

IF3.9

2016-05-13

OAAI

Velikova, Nadya; Fulle, Simone; Manso, Ana Sousa; Mechkarska, Milena; Finn, Paul; Conlon, J. Michael; Oggioni, Marco Rinaldo; Wells, Jerry M.; Marina, Alberto

Exploration of Piperidinols as Potential Antitubercular Agents

MOLECULES

IF4.6

2014-10-10

OAAI

Abuhammad, Areej; Fullam, Elizabeth; Bhakta, Sanjib; Russell, Angela J.; Morris, Garrett M.; Finn, Paul W.; Sim, Edith

The cloud and other new computational methods to improve molecular modelling

EXPERT OPINION ON DRUG DISCOVERY

IF4.9

2014-08-22

PREAI

Korb, Oliver; Finn, Paul W.; Jones, Gareth

Reranking Docking Poses Using Molecular Simulations and Approximate Free Energy Methods

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2014-07-31

PREAI

Lauro, G.; Ferruz, N.; Fulle, S.; Harvey, M. J.; Finn, P. W.; De Fabritiis, G.

Comparison of ultra-fast 2D and 3D ligand and target descriptors for side effect prediction and network analysis in polypharmacology 超快速2D和3D配体和靶标描述符在多药理学中用于副作用预测和网络分析的比较

BRITISH JOURNAL OF PHARMACOLOGY

IF7.7

2013-09-17

OAAI

Cortes-Cabrera, Alvaro; Morris, Garrett M.; Finn, Paul W.; Morreale, Antonio; Gago, Federico

Molecular Determinants of Binding to the Plasmodium Subtilisin-like Protease 1

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2013-03-04

OAAI

Fulle, Simone; Withers-Martinez, Chrislaine; Blackman, Michael J.; Morris, Garrett M.; Finn, Paul W.

WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE

IF27

2012-11-12

PREAI

Finn, Paul W.; Morris, Garrett M.

Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target

INTERNATIONAL JOURNAL FOR PARASITOLOGY

IF3.2

2012-05-01

OAAI

Withers-Martinez, Chrislaine; Suarez, Catherine; Fulle, Simone; Kher, Samir; Penzo, Maria; Ebejer, Jean-Paul; Koussis, Kostas; Hackett, Fiona; Jirgensons, Aigars; Finn, Paul; Blackman, Michael J.

Improving the accuracy of ultrafast ligand-based screening: incorporating lipophilicity into ElectroShape as an extra dimension

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2011-08-06

PREAI

Armstrong, M. Stuart; Finn, Paul W.; Morris, Garrett M.; Richards, W. Graham

ElectroShape: fast molecular similarity calculations incorporating shape, chirality and electrostatics

JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

IF3.1

2010-07-08

PREAI

Armstrong, M. Stuart; Morris, Garrett M.; Finn, Paul W.; Sharma, Raman; Moretti, Loris; Cooper, Richard I.; Richards, W. Graham

Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo 联合抑制DNA甲基化和组蛋白乙酰化增强体内基因再表达和药物敏感性

BRITISH JOURNAL OF CANCER

IF6.8

2009-03-03

145

OAAI

Steele, N.; Finn, P.; Brown, R.; Plumb, J. A.

Novel amide derivatives as inhibitors of histone deacetylase: Design, synthesis and SAR

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2009-03-01

PREAI

Andrianov, Victor; Gailite, Vija; Lola, Daina; Loza, Einars; Semenikhina, Valentina; Kalvinsh, Ivars; Finn, Paul; Petersen, Kamille Dumong; Ritchie, James W. A.; Khan, Nagma; Tumber, Anthony; Collins, Laura S.; Vadlamudi, Sree M.; Bjorkling, Fredrik; Sehested, Maxwell

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors 小分子组蛋白去乙酰化酶抑制剂的种类和异构体选择性的测定

BIOCHEMICAL JOURNAL

IF4.3

2007-12-21

721

OAAI

Khan, Nagma; Jeffers, Michael; Kumar, Sampath; Hackett, Craig; Boldog, Ferenc; Khramtsov, Nicholai; Qian, Xiaozhong; Mills, Evan; Berghs, Stanny C.; Carey, Nessa; Finn, Paul W.; Collins, Laura S.; Tumber, Anthony; Ritchie, James W.; Jensen, Peter Buhl; Lichenstein, Henri S.; Sehested, Maxwell

Quantitative proteomic analysis of posttranslational modifications of human histones

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2006-07-01

204

OAAI

Beck, Hans Christian; Nielsen, Eva C.; Matthiesen, Rune; Jensen, Lars H.; Sehested, Maxwell; Finn, Paul; Grauslund, Morten; Hansen, Anne Maria; Jensen, Ole Norregaard

研究方向