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Paresh Vyas

University of Oxford
H指数:93
被引数:4.4万

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The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome
Leukemia
IF13.4
2026-07-210
OA
Austin C. Boucher; Wojciech Rosikiewicz; Anitria Cotton; Amber L. Broadhurst; Te Ling; Rishika Vadlamudi; Melanie Bremm; Anna-Lena Schmell; Lahiri Konada; Madeline Niederkorn; Josiah D. Murray; Yichao Li; Shilpa Narina; Sarah Inglott; Anindita Roy; Philip Ancliff; Ricky Tirtakusuma; Jing Ma; Michael P. Walsh; Jeffery M. Klco; Paul G. Thomas; Yiwen Wang; Aristotelis Tsirigos; Yong Cheng; Beisi Xu; Xiaotu Ma; Soheil Meshinchi; Elvin Wagenblast; Shondra M. Pruett-Miller; Sridhar Rao; Gang Wu; Yunusa Olufadi; Guolian Kang; Zuzana Tothova; Jeffrey W. Taub; Yubin Ge; Paresh Vyas; Jan-Henning Klusmann; John D. Crispino
Human haematopoietic stem cells remember inflammatory stress

人类造血干细胞能够记忆炎症应激

Nature
IF48.5
2026-05-270
OAAI
Andy G. X. Zeng; Murtaza S. Nagree; Niels Asger Jakobsen; Sayyam Shah; Angelica Varesi; Jasmine Ryu Won Kang; Alex Murison; Jin-Gyu Cheong; Sven Turkalj; Xuan Zhang; Felix A. Radtke; Tsega-Ab Abera; Isabel N. X. Lim; Liqing Jin; Joana Araújo; Alicia G. Aguilar-Navarro; Darrien Parris; Jessica McLeod; Hyerin Kim; Ho Seok Lee; Lin Zhang; Mason Boulanger; Elyssa Bader; Elias Gbeha; Christopher N. Parkhurst; Elvin Wagenblast; Eugenia Flores-Figueroa; Bo Wang; Gregory W. Schwartz; Leonard D. Shultz; Anna S. Nam; H. Leighton Grimes; Steven Z. Josefowicz; Philip Awadalla; Paresh Vyas; John E. Dick; Stephanie Z. Xie
Initial leukemic epigenomic state determines hypomethylating agent response

初始白血病表观基因组状态决定去甲基化药物的反应

Nature Communications
IF15.7
2026-05-010
PRE
Gopal, Aparna; Tam, Derek; Mey, Franziska; Lin, Diana; May, Christina; Jiang, Jihong; Bridgers, Joshua; Caswell, Brett; O'Neill, Kieran; Vizeacoumar, Frederick S.; MacAuley, Mackenzie; Haniak, Emilie; Craddock, Charles; Vyas, Paresh; Malcovati, Luca; Buckstein, Rena; Moksa, Michelle; Hirst, Martin; Vizeacoumar, Franco J.; Medvedev, Nadia; Heuser, Michael; Stubbins, Ryan J.; Deng, Yu; Karsan, Aly
MYB activity drives emergent enhancer activation and enhancer-promoter interactions in acute lymphoblastic leukemia

MYB活性驱动急性淋巴细胞白血病中增强子的涌现激活和增强子-启动子相互作用

Blood
IF23.1
2026-03-230
PRE
I-Jun Lau; Gianna Bloye; Alastair L. Smith; Joe R. Harman; Joseph C. Hamley; Vassilena Sharlandjieva; Nicholas Denny; Catherine Chahrour; Hangpeng Li; Nicole E. Jackson; Paresh Vyas; James O.J. Davies; Jim R. Hughes; Nicholas T. Crump; Thomas A. Milne
Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy

早期造血细胞群内的快速克隆选择预示ivosidenib联合治疗的结局

Blood
IF23.1
2025-11-070
PRE
Sven Turkalj; Felix A. Radtke; Bilyana Stoilova; Rabea Mecklenbrauck; Angus J. Groom; Niels Asger Jakobsen; Curtis A. Lachowiez; Marlen Metzner; Batchimeg Usukhbayar; Mirian Angulo Salazar; Zhihong Zeng; Sanam Loghavi; Jennifer Marvin-Peek; Verena Körber; Farhad Ravandi; Ghayas Issa; Tapan Kadia; Vasiliki Symeonidou; Anne P. de Groot; Hagop Kantarjian; Koichi Takahashi; Marina Konopleva; Courtney D. DiNardo; Paresh Vyas
Detecting and quantifying clonal selection in somatic stem cells

检测和量化体干细胞中的克隆选择

Nature Genetics
IF0
2025-07-030
OA
Verena Körber; Niels Asger Jakobsen; Naser Ansari-Pour; Rachel Moore; Nina Claudino; Marlen Metzner; Eva Thielecke; Franziska Esau; Batchimeg Usukhbayar; Mirian Angulo Salazar; Simon Newman; Benjamin J. L. Kendrick; Adrian H. Taylor; Rasheed Afinowi-Luitz; Roger Gundle; Bridget Watkins; Kim Wheway; Debra Beazley; Stephanie G. Dakin; Antony Palmer; Andrew J. Carr; Paresh Vyas; Thomas Höfer
Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome

Down综合征儿童中前白血病性体细胞GATA1突变的临床意义

Blood
IF23.1
2025-06-270
OA
Natalina Elliott; Neha Bhatnagar; Gemma Buck; David Cruz Hernandez; Kelly Perkins; Adam J. de Smith; Amelie Chaussade; Laure Nizery; Marlen Metzner; Catherine Garnett; Alice Norton; Alison Kennedy; Triya Chakravorty; Dylan Zhao; Lars Hanssen; Georgina Hall; Paresh Vyas; Irene Roberts
A revised prognostic model for patients with acute myeloid leukemia and first relapse

针对急性髓系白血病首次复发的修订型预后模型

Blood Advances
IF7.1
2025-05-260
OA
Niek G. van der Maas; Dimitri Breems; Clara P. W. Klerk; Thomas Pabst; Patrycja Gradowska; Abin Thomas; Bart J. Biemond; Jurgen Kuball; Catharina H. M. J. Van Elssen; Otto Visser; Marie-Christiane Vekemans; Carlos Graux; Johan Maertens; Steven Knapper; Mike Dennis; Sylvie Freeman; Ian Thomas; H. Berna Beverloo; Gerwin Huls; Charles Craddock; Peter J. M. Valk; Paresh Vyas; Nigel Russell; Gert Ossenkoppele; Bob Löwenberg; Jan J. Cornelissen; Jurjen Versluis
Clonal tracing with somatic epimutations reveals dynamics of blood ageing

利用体细胞表观突变进行克隆追踪揭示了血液衰老的动态过程

NATURE
IF48.5
2025-05-210
OA
Scherer, Michael; Singh, Indranil; Braun, Martina Maria; Szu-Tu, Chelsea; Sanchez Sanchez, Pedro; Lindenhofer, Dominik; Jakobsen, Niels Asger; Korber, Verena; Kardorff, Michael; Nitsch, Lena; Kautz, Pauline; Ruhle, Julia; Bianchi, Agostina; Cozzuto, Luca; Fromel, Robert; Beneyto-Calabuig, Sergi; Lareau, Caleb; Satpathy, Ansuman T.; Beekman, Renee; Steinmetz, Lars M.; Raffel, Simon; Ludwig, Leif S.; Vyas, Paresh; Velten, Lars
Bleximenib Dose Optimization and Determination of RP2D from a Phase 1 Study in Relapsed/Refractory Acute Leukemia Patients with KMT2A and NPM1 Alterations

Bleximenib剂量优化及携带KMT2A和NPM1基因变异的复发/难治性急性白血病患者1期研究的RP2D确定

BLOOD
IF23.1
2024-11-055
PRE
Searle, Emma; Recher, Christian; Abdul-Hay, Maher; Abedin, Sameem; Aldoss, Ibrahim; Pierola, Ana Alfonso; Alonso-Dominguez, Juan M.; Chevallier, Patrice; Cost, Carrye; Daskalakis, Nikki; Dillon, Richard; Dunavin, Neil; Esteve, Jordi; Fathi, Amir T.; Fedele, Pasquale L.; Ferrante, Lucille; Gaj, Stan; Guttke, Christina; Gyan, Emmanuel; Hiebert, Brett; Jabbour, Elias; Kantarjian, Hagop M.; Kwon, Min Chul; Kumar, Anita J.; Ng, Teng Fong; Packman, Kathryn; Philippar, Ulrike; Pigneux, Arnaud; Salamero, Olga; Sanga, Madhu; Shastri, Prathap Nagaraja; Stone, Richard M.; Tan, Peter; Tucker, Trevor; Vyas, Paresh; Garciaz, Sylvain
Mutational Landscape and Depth of Response in Patients with Acute Myeloid Leukemia (AML) Treated with Magrolimab in Combination with Venetoclax and Azacitidine Compared to Placebo

急性髓系白血病（AML）患者接受magrolimab联合venetoclax和azacitidine治疗与安慰剂治疗的突变景观和应答深度比较

BLOOD
IF23.1
2024-11-051
PRE
Johnson, Lisa D. S.; Tang, Shan; Zhang, Yajia; Metzner, Marlen; Aviles, Lisa; Kavelaars, Francois; Morrow, Eyelet; Vitters, Damien; Caldwell, Kenneth; Valk, Peter J. M.; Vyas, Paresh
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging

突变干细胞在人类克隆造血中的选择性优势与对炎症和衰老的反应减弱有关

CELL STEM CELL
IF20.4
2024-08-016
OAAI
Jakobsen, Niels Asger; Turkalj, Sven; Zeng, Andy G. X.; Stoilova, Bilyana; Metzner, Marlen; Rahmig, Susann; Nagree, Murtaza S.; Shah, Sayyam; Moore, Rachel; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Gafencu, Grigore-Aristide; Kennedy, Alison; Newman, Simon; Kendrick, Benjamin J. L.; Taylor, Adrian H.; Afinowi-Luitz, Rasheed; Gundle, Roger; Watkins, Bridget; Wheway, Kim; Beazley, Debra; Murison, Alex; Aguilar-Navarro, Alicia G.; Flores-Figueroa, Eugenia; Dakin, Stephanie G.; Carr, Andrew J.; Nerlov, Claus; Dick, John E.; Xie, Stephanie Z.; Vyas, Paresh
Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia
RSC MEDICINAL CHEMISTRY
IF3.6
2024-01-011
OAAI
Cogswell, Thomas J.; Josa-Cullere, Laia; Zimmer, David; Galan, Sebastien R. G.; Jay-Smith, Morgan; Harris, Kate S.; Bataille, Carole J. R.; Jackson, Thomas R.; Zhang, Douzi; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Wynne, Graham M.; Russell, Angela J.
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2023-10-013
PRE
Josa-Cullere, Laia; Galan, Sebastien R. G.; Cogswell, Thomas J.; Jackson, Thomas R.; Jay-Smith, Morgan; Mola, Laura; Greaves, Christopher R.; Carter, Tom S.; Madden, Katrina S.; Trott, Sophie; Zhang, Douzi; Bataille, Carole J. R.; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Naylor, Alan; Wynne, Graham M.; Russell, Angela J.
A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in IDH1-Mutated Myeloid Malignancies
BLOOD CANCER DISCOVERY
IF11.5
2023-04-2651
OA
Lachowiez, Curtis A.; Loghavi, Sanam; Zeng, Zhihong; Tanaka, Tomoyuki; Kim, Yi June; Uryu, Hidetaka; Turkalj, Sven; Jakobsen, Niels Asger; Luskin, Marlise R.; Duose, Dzifa Y.; Tidwell, Rebecca S. S.; Short, Nicholas J.; Borthakur, Gautam; Kadia, Tapan M.; Masarova, Lucia; Tippett, George D.; Bose, Prithviraj; Jabbour, Elias J.; Ravandi, Farhad; Daver, Naval G.; Garcia-Manero, Guillermo; Kantarjian, Hagop; Garcia, Jacqueline S.; Vyas, Paresh; Takahashi, Koichi; Konopleva, Marina; DiNardo, Courtney D.

研究方向

暂未获取到该数据
M
Marlen Metzner
H 指数:15论文数:64被引数:2,167
I
Irene Roberts
H 指数:74论文数:396被引数:2.4万
C
Catherine Porcher
H 指数:26论文数:69被引数:3,839
L
Lynn Quek
H 指数:29论文数:114被引数:6,609
N
Niels Asger Jakobsen
H 指数:12论文数:51被引数:527
B
Bilyana Stoilova
H 指数:13论文数:32被引数:1,167
C
Charles Craddock
H 指数:72论文数:545被引数:2.1万
B
Batchimeg Usukhbayar
H 指数:8论文数:30被引数:710
N
Nigel H. Russell
H 指数:78论文数:624被引数:2.4万
S
Sven Turkalj
H 指数:9论文数:37被引数:464