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Paresh Vyas

weatherall institute for molecular medicine

93H指数
621论文数
4.4W被引数
收录论文 101
发表时间
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The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome
errLeukemia
IF13.4
err2026-07-21
err0
errOAAI
errAustin C. Boucher; Wojciech Rosikiewicz; Anitria Cotton; Amber L. Broadhurst; Te Ling; Rishika Vadlamudi; Melanie Bremm; Anna-Lena Schmell; Lahiri Konada; Madeline Niederkorn; Josiah D. Murray; Yichao Li; Shilpa Narina; Sarah Inglott; Anindita Roy; Philip Ancliff; Ricky Tirtakusuma; Jing Ma; Michael P. Walsh; Jeffery M. Klco; Paul G. Thomas; Yiwen Wang; Aristotelis Tsirigos; Yong Cheng; Beisi Xu; Xiaotu Ma; Soheil Meshinchi; Elvin Wagenblast; Shondra M. Pruett-Miller; Sridhar Rao; Gang Wu; Yunusa Olufadi; Guolian Kang; Zuzana Tothova; Jeffrey W. Taub; Yubin Ge; Paresh Vyas; Jan-Henning Klusmann; John D. Crispino
err分享
err收藏
Human haematopoietic stem cells remember inflammatory stress人类造血干细胞能够记忆炎症应激
errNature
IF48.5
err2026-05-27
err0
errOAAI
errAndy G. X. Zeng; Murtaza S. Nagree; Niels Asger Jakobsen; Sayyam Shah; Angelica Varesi; Jasmine Ryu Won Kang; Alex Murison; Jin-Gyu Cheong; Sven Turkalj; Xuan Zhang; Felix A. Radtke; Tsega-Ab Abera; Isabel N. X. Lim; Liqing Jin; Joana Araújo; Alicia G. Aguilar-Navarro; Darrien Parris; Jessica McLeod; Hyerin Kim; Ho Seok Lee; Lin Zhang; Mason Boulanger; Elyssa Bader; Elias Gbeha; Christopher N. Parkhurst; Elvin Wagenblast; Eugenia Flores-Figueroa; Bo Wang; Gregory W. Schwartz; Leonard D. Shultz; Anna S. Nam; H. Leighton Grimes; Steven Z. Josefowicz; Philip Awadalla; Paresh Vyas; John E. Dick; Stephanie Z. Xie
err分享
err收藏
MYB activity drives emergent enhancer activation and enhancer-promoter interactions in acute lymphoblastic leukemiaMYB活性驱动急性淋巴细胞白血病中增强子的涌现激活和增强子-启动子相互作用
errBlood
IF23.1
err2026-03-23
err0
PREAI
errI-Jun Lau; Gianna Bloye; Alastair L. Smith; Joe R. Harman; Joseph C. Hamley; Vassilena Sharlandjieva; Nicholas Denny; Catherine Chahrour; Hangpeng Li; Nicole E. Jackson; Paresh Vyas; James O.J. Davies; Jim R. Hughes; Nicholas T. Crump; Thomas A. Milne
err分享
err收藏
Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy早期造血细胞群内的快速克隆选择预示ivosidenib联合治疗的结局
errBlood
IF23.1
err2025-11-07
err0
PREAI
errSven Turkalj; Felix A. Radtke; Bilyana Stoilova; Rabea Mecklenbrauck; Angus J. Groom; Niels Asger Jakobsen; Curtis A. Lachowiez; Marlen Metzner; Batchimeg Usukhbayar; Mirian Angulo Salazar; Zhihong Zeng; Sanam Loghavi; Jennifer Marvin-Peek; Verena Körber; Farhad Ravandi; Ghayas Issa; Tapan Kadia; Vasiliki Symeonidou; Anne P. de Groot; Hagop Kantarjian; Koichi Takahashi; Marina Konopleva; Courtney D. DiNardo; Paresh Vyas
err分享
err收藏
Patient involvement in the design of ALIDHE: a study of ivosidenib plus azacitidine in newly diagnosed IDH1 mutant AMLALIDHE设计中的患者参与：一项关于ivosidenib联合阿扎胞苷治疗新诊断IDH1突变型AML的研究
errFUTURE ONCOLOGY
IF2.6
err2025-11-01
err1
PREAI
errNier, Samantha; Pelouchova, Jana; Hills, Ralph; Salek, Sam; Derrien, Helene; Chatin, Stephanie; De La Bigne, Anne-Marie; Vives, Susana; Recher, Christian; Doehner, Hartmut; Venditti, Adriano; Vyas, Paresh
err分享
err收藏
Detecting and quantifying clonal selection in somatic stem cells检测和量化体干细胞中的克隆选择
errNature Genetics
IF0
err2025-07-03
err0
errOAAI
errVerena Körber; Niels Asger Jakobsen; Naser Ansari-Pour; Rachel Moore; Nina Claudino; Marlen Metzner; Eva Thielecke; Franziska Esau; Batchimeg Usukhbayar; Mirian Angulo Salazar; Simon Newman; Benjamin J. L. Kendrick; Adrian H. Taylor; Rasheed Afinowi-Luitz; Roger Gundle; Bridget Watkins; Kim Wheway; Debra Beazley; Stephanie G. Dakin; Antony Palmer; Andrew J. Carr; Paresh Vyas; Thomas Höfer
err分享
err收藏
Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndromeDown综合征儿童中前白血病性体细胞GATA1突变的临床意义
errBlood
IF23.1
err2025-06-27
err0
errOAAI
errNatalina Elliott; Neha Bhatnagar; Gemma Buck; David Cruz Hernandez; Kelly Perkins; Adam J. de Smith; Amelie Chaussade; Laure Nizery; Marlen Metzner; Catherine Garnett; Alice Norton; Alison Kennedy; Triya Chakravorty; Dylan Zhao; Lars Hanssen; Georgina Hall; Paresh Vyas; Irene Roberts
err分享
err收藏
A revised prognostic model for patients with acute myeloid leukemia and first relapse针对急性髓系白血病首次复发的修订型预后模型
errBlood Advances
IF7.1
err2025-05-26
err0
errOAAI
errNiek G. van der Maas; Dimitri Breems; Clara P. W. Klerk; Thomas Pabst; Patrycja Gradowska; Abin Thomas; Bart J. Biemond; Jurgen Kuball; Catharina H. M. J. Van Elssen; Otto Visser; Marie-Christiane Vekemans; Carlos Graux; Johan Maertens; Steven Knapper; Mike Dennis; Sylvie Freeman; Ian Thomas; H. Berna Beverloo; Gerwin Huls; Charles Craddock; Peter J. M. Valk; Paresh Vyas; Nigel Russell; Gert Ossenkoppele; Bob Löwenberg; Jan J. Cornelissen; Jurjen Versluis
err分享
err收藏
Clonal tracing with somatic epimutations reveals dynamics of blood ageing利用体细胞表观突变进行克隆追踪揭示了血液衰老的动态过程
errNATURE
IF48.5
err2025-05-21
err0
errOAAI
errScherer, Michael; Singh, Indranil; Braun, Martina Maria; Szu-Tu, Chelsea; Sanchez Sanchez, Pedro; Lindenhofer, Dominik; Jakobsen, Niels Asger; Korber, Verena; Kardorff, Michael; Nitsch, Lena; Kautz, Pauline; Ruhle, Julia; Bianchi, Agostina; Cozzuto, Luca; Fromel, Robert; Beneyto-Calabuig, Sergi; Lareau, Caleb; Satpathy, Ansuman T.; Beekman, Renee; Steinmetz, Lars M.; Raffel, Simon; Ludwig, Leif S.; Vyas, Paresh; Velten, Lars
err分享
err收藏
Genome-wide association study of somatic GATA1s mutations in newborns with Down syndrome新生儿唐氏综合征中体细胞GATA1s突变的全基因组关联研究
errBlood Advances
IF7.1
err2025-04-21
err0
errOAAI
errYunqi Li; Natalina Elliott; Patricia Lein; Paresh Vyas; Irene Roberts; Adam J. de Smith
err分享
err收藏
Bleximenib Dose Optimization and Determination of RP2D from a Phase 1 Study in Relapsed/Refractory Acute Leukemia Patients with KMT2A and NPM1 AlterationsBleximenib剂量优化及携带KMT2A和NPM1基因变异的复发/难治性急性白血病患者1期研究的RP2D确定
errBLOOD
IF23.1
err2024-11-05
err5
PREAI
errSearle, Emma; Recher, Christian; Abdul-Hay, Maher; Abedin, Sameem; Aldoss, Ibrahim; Pierola, Ana Alfonso; Alonso-Dominguez, Juan M.; Chevallier, Patrice; Cost, Carrye; Daskalakis, Nikki; Dillon, Richard; Dunavin, Neil; Esteve, Jordi; Fathi, Amir T.; Fedele, Pasquale L.; Ferrante, Lucille; Gaj, Stan; Guttke, Christina; Gyan, Emmanuel; Hiebert, Brett; Jabbour, Elias; Kantarjian, Hagop M.; Kwon, Min Chul; Kumar, Anita J.; Ng, Teng Fong; Packman, Kathryn; Philippar, Ulrike; Pigneux, Arnaud; Salamero, Olga; Sanga, Madhu; Shastri, Prathap Nagaraja; Stone, Richard M.; Tan, Peter; Tucker, Trevor; Vyas, Paresh; Garciaz, Sylvain
err分享
err收藏
Mutational Landscape and Depth of Response in Patients with Acute Myeloid Leukemia (AML) Treated with Magrolimab in Combination with Venetoclax and Azacitidine Compared to Placebo急性髓系白血病（AML）患者接受magrolimab联合venetoclax和azacitidine治疗与安慰剂治疗的突变景观和应答深度比较
errBLOOD
IF23.1
err2024-11-05
err1
PREAI
errJohnson, Lisa D. S.; Tang, Shan; Zhang, Yajia; Metzner, Marlen; Aviles, Lisa; Kavelaars, Francois; Morrow, Eyelet; Vitters, Damien; Caldwell, Kenneth; Valk, Peter J. M.; Vyas, Paresh
err分享
err收藏
Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved
errSCIENCE IMMUNOLOGY
IF16.3
err2024-08-23
err1
PREAI
errAksoez, Merve; Gafencu, Grigore-Aristide; Stoilova, Bilyana; Buono, Mario; Zhang, Ying; Turkalj, Sven; Meng, Yiran; Jakobsen, Niels Asger; Metzner, Marlen; Clark, Sally-Ann; Beveridge, Ryan; Thongjuea, Supat; Vyas, Paresh; Nerlov, Claus
err分享
err收藏
Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging突变干细胞在人类克隆造血中的选择性优势与对炎症和衰老的反应减弱有关
errCELL STEM CELL
IF20.4
err2024-08-01
err6
errOAAI
errJakobsen, Niels Asger; Turkalj, Sven; Zeng, Andy G. X.; Stoilova, Bilyana; Metzner, Marlen; Rahmig, Susann; Nagree, Murtaza S.; Shah, Sayyam; Moore, Rachel; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Gafencu, Grigore-Aristide; Kennedy, Alison; Newman, Simon; Kendrick, Benjamin J. L.; Taylor, Adrian H.; Afinowi-Luitz, Rasheed; Gundle, Roger; Watkins, Bridget; Wheway, Kim; Beazley, Debra; Murison, Alex; Aguilar-Navarro, Alicia G.; Flores-Figueroa, Eugenia; Dakin, Stephanie G.; Carr, Andrew J.; Nerlov, Claus; Dick, John E.; Xie, Stephanie Z.; Vyas, Paresh
err分享
err收藏
Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia
errRSC MEDICINAL CHEMISTRY
IF3.6
err2024-01-01
err1
errOAAI
errCogswell, Thomas J.; Josa-Cullere, Laia; Zimmer, David; Galan, Sebastien R. G.; Jay-Smith, Morgan; Harris, Kate S.; Bataille, Carole J. R.; Jackson, Thomas R.; Zhang, Douzi; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Wynne, Graham M.; Russell, Angela J.
err分享
err收藏
Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-10-01
err3
PREAI
errJosa-Cullere, Laia; Galan, Sebastien R. G.; Cogswell, Thomas J.; Jackson, Thomas R.; Jay-Smith, Morgan; Mola, Laura; Greaves, Christopher R.; Carter, Tom S.; Madden, Katrina S.; Trott, Sophie; Zhang, Douzi; Bataille, Carole J. R.; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Naylor, Alan; Wynne, Graham M.; Russell, Angela J.
err分享
err收藏
An Overview of Targeted Therapies in Acute Myeloid Leukemia
errHEMASPHERE
IF14.6
err2023-06-01
err12
errOAAI
errTurkalj, Sven; Radtke, Felix A.; Vyas, Paresh
err分享
err收藏
GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells
errCELL STEM CELL
IF20.4
err2023-05-01
err7
errOAAI
errTurkalj, Sven; Jakobsen, Niels Asger; Groom, Angus; Metzner, Marlen; Riva, Simone G.; Gur, E. Ravza; Usukhbayar, Batchimeg; Salazar, Mirian Angulo; Hentges, Lance D.; Mickute, Gerda; Clark, Kevin; Sopp, Paul; Davies, James O. J.; Hughes, Jim R.; Vyas, Paresh
err分享
err收藏
A Phase Ib/II Study of Ivosidenib with Venetoclax ± Azacitidine in IDH1-Mutated Myeloid Malignancies
errBLOOD CANCER DISCOVERY
IF11.5
err2023-04-26
err51
errOAAI
errLachowiez, Curtis A.; Loghavi, Sanam; Zeng, Zhihong; Tanaka, Tomoyuki; Kim, Yi June; Uryu, Hidetaka; Turkalj, Sven; Jakobsen, Niels Asger; Luskin, Marlise R.; Duose, Dzifa Y.; Tidwell, Rebecca S. S.; Short, Nicholas J.; Borthakur, Gautam; Kadia, Tapan M.; Masarova, Lucia; Tippett, George D.; Bose, Prithviraj; Jabbour, Elias J.; Ravandi, Farhad; Daver, Naval G.; Garcia-Manero, Guillermo; Kantarjian, Hagop; Garcia, Jacqueline S.; Vyas, Paresh; Takahashi, Koichi; Konopleva, Marina; DiNardo, Courtney D.
err分享
err收藏
Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1
errMOLECULAR AND CELLULAR BIOLOGY
IF2.7
err2023-03-27
err40
errOAAI
errSchlaeger, TM; Schuh, A; Flitter, S; Fisher, A; Mikkola, H; Orkin, SH; Vyas, P; Porcher, C
err分享
err收藏

研究方向

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合作学者
合作期刊
H
Hagop M. Kantarjian
H 指数: 230 · 论文数: 5.5K
I
Irving L. Weissman
H 指数: 215 · 论文数: 1.3K
S
Stuart H. Orkin
H 指数: 179 · 论文数: 797
T
Todd R. Golub
H 指数: 176 · 论文数: 749
P
P. Andrew Futreal
H 指数: 159 · 论文数: 1.3K
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