未登录 Reprogramming CBX8-PRC1 function with a positive allosteric modulator Suh, Junghyun L.; Bsteh, Daniel; Hart, Bryce; Si, Yibo; Weaver, Tyler M.; Pribitzer, Carina; Lau, Roy; Soni, Shivani; Ogana, Heather; Rectenwald, Justin M.; Norris, Jacqueline L.; Cholensky, Stephanie H.; Sagum, Cari; Umana, Jessica D.; Li, Dongxu; Hardy, Brian; Bedford, Mark T.; Mumenthaler, Shannon M.; Lenz, Heinz-Josef; Kim, Yong-Mi; Wang, Gang Greg; Pearce, Ken H.; James, Lindsey, I; Kireev, Dmitri B.; Musselman, Catherine A.; Frye, Stephen, V; Bell, Oliver 分享 收藏
Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7 Lamb, Kelsey N.; Bsteh, Daniel; Dishman, Sarah N.; Moussa, Hagar F.; Fan, Huitao; Stuckey, Jacob I.; Norris, Jacqueline L.; Cholensky, Stephanie H.; Li, Dongxu; Wang, Jingkui; Sagum, Cari; Stanton, Benjamin Z.; Bedford, Mark T.; Pearce, Kenneth H.; Kenakin, Terry P.; Kireev, Dmitri B.; Wang, Gang Greg; James, Lindsey I.; Bell, Oliver; Frye, Stephen V. 分享 收藏
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 (vol 12, pg 180, 2016) Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Brown, Peter J.; TBedford, Mark; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
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A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Browne, Peter J.; Bedford, Mark T.; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
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Targeting chromatin regulation for cancer therapy: progress towards chemical probes for methyl-lysine readers James, Lindsey I.; Stuckey, Jake I.; Baughman, Brandi M.; Perfetti, Michael T.; Pattenden, Samantha G.; Dickson, Brad M.; Norris, Jacqueline L.; Cui, Gaofeng; Mader, Pavel; Dong, Aiping; Mu, Yunxiang; Rothbart, Scott B.; Strahl, Brian D.; Min, Jinrong; Brown, Peter J.; Kireev, Dmitri B.; Janzen, William P.; McBride, Kevin M.; Bedford, Mark T.; Mer, Georges; Arrowsmith, Cheryl H.; Frye, Stephen V. 分享 收藏
Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1 Perfetti, Michael T.; Baughman, Brandi M.; Dickson, Bradley M.; Mu, Yunxiang; Cui, Gaofeng; Mader, Pavel; Dong, Aiping; Norris, Jacqueline L.; Rothbart, Scott B.; Strahl, Brian D.; Brown, Peter J.; Janzen, William P.; Arrowsmith, Cheryl H.; Mer, Georges; McBride, Kevin M.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8 Ma, Anqi; Yu, Wenyu; Li, Fengling; Bleich, Rachel M.; Herold, J. Martin; Butler, Kyle V.; Norris, Jacqueline L.; Korboukh, Victoria; Tripathy, Ashutosh; Janzen, William P.; Arrowsmith, Cheryl H.; Frye, Stephen V.; Vedadi, Masoud; Brown, Peter J.; Jin, Jian 分享 收藏
Small-Molecule Ligands of Methyl-Lysine Binding Proteins: Optimization of Selectivity for L3MBTL3 James, Lindsey I.; Korboukh, Victoria K.; Krichevsky, Liubov; Baughman, Brandi M.; Herold, J. Martin; Norris, Jacqueline L.; Jin, Jian; Kireev, Dmitri B.; Janzen, William P.; Arrowsmith, Cheryl H.; Frye, Stephen V. 分享 收藏
An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1 赖氨酸甲基转移酶EZH2和EZH1的口服生物可利用化学探针 Konze, Kyle D.; Ma, Anqi; Li, Fengling; Barsyte-Lovejoy, Dalia; Parton, Trevor; MacNevin, Christopher J.; Liu, Feng; Gao, Cen; Huang, Xi-Ping; Kuznetsova, Ekaterina; Rougie, Marie; Jiang, Alice; Pattenden, Samantha G.; Norris, Jacqueline L.; James, Lindsey I.; Roth, Bryan L.; Brown, Peter J.; Frye, Stephen V.; Arrowsmith, Cheryl H.; Hahn, Klaus M.; Wang, Gang Greg; Vedadi, Masoud; Jin, Jian 分享 收藏
Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain James, Lindsey I.; Barsyte-Lovejoy, Dalia; Zhong, Nan; Krichevsky, Liubov; Korboukh, Victoria K.; Herold, J. Martin; MacNevin, Christopher J.; Norris, Jacqueline L.; Sagum, Cari A.; Tempel, Wolfram; Marcon, Edyta; Guo, Hongbo; Gao, Cen; Huang, Xi-Ping; Duan, Shili; Emili, Andrew; Greenblatt, Jack F.; Kireev, Dmitri B.; Jin, Jian; Janzen, William P.; Brown, Peter J.; Bedford, Mark T.; Arrowsmith, Cheryl H.; Frye, Stephen V. 分享 收藏
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells (vol 7, pg 566, 2011) Vedadi, Masoud; Barsyte-Lovejoy, Dalia; Liu, Feng; Rival-Gervier, Sylvie; Allali-Hassani, Abdellah; Labrie, Viviane; Wigle, Tim J.; DiMaggio, Peter A.; Wasney, Gregory A.; Siarheyeva, Alena; Dong, Aiping; Tempel, Wolfram; Wang, Sun-Chong; Chen, Xin; Chau, Irene; Mangano, Thomas J.; Huang, Xi-ping; Simpson, Catherine D.; Pattenden, Samantha G.; Norris, Jacqueline L.; Kireev, Dmitri B.; Tripathy, Ashutosh; Edwards, Aled; Roth, Bryan L.; Janzen, William P.; Garcia, Benjamin A.; Petronis, Arturas; Ellis, James; Brown, Peter J.; Frye, Stephen V.; Arrowsmith, Cheryl H.; Jin, Jian 分享 收藏
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Small-Molecule Ligands of Methyl-Lysine Binding Proteins Herold, J. Martin; Wigle, Tim J.; Norris, Jacqueline L.; Lam, Robert; Korboukh, Victoria K.; Gao, Cen; Ingerman, Lindsey A.; Kireev, Dmitri B.; Senisterra, Guillermo; Vedadi, Masoud; Tripathy, Ashutosh; Brown, Peter J.; Arrowsmith, Cheryl H.; Jin, Jian; Janzen, William P.; Frye, Stephen V. 分享 收藏
Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines. Liu, Feng; Chen, Xin; Allali-Hassani, Abdellah; Quinn, Amy M.; Wigle, Tim J.; Wasney, Gregory A.; Dong, Aiping; Senisterra, Guillermo; Chau, Irene; Siarheyeva, Alena; Norris, Jacqueline L.; Kireev, Dmitri B.; Jadhav, Ajit; Herold, J. Martin; Janzen, William P.; Arrowsmith, Cheryl H.; Frye, Stephen V.; Brown, Peter J.; Simeonov, Anton; Vedadi, Masoud; Jin, Jian 分享 收藏
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