Henry I. Yamamura - Publications, H-index & Citations

Henry I. Yamamura

University of Arizona

87H指数

626论文数

2.8W被引数

收录论文 66

发表时间

Discovery of a Potent and Efficacious Peptide Derivative for δ/μ Opioid Agonist/Neurokinin 1 Antagonist Activity with a 2′,6′-Dimethyl-L-Tyrosine: In vitro, In vivo, and NMR-Based Structural Studies

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2011-03-02

OAAI

Yamamoto, Takashi; Nair, Padma; Largent-Milnes, Tally M.; Jacobsen, Neil E.; Davis, Peg; Ma, Shou-Wu; Yamamura, Henry I.; Vanderah, Todd W.; Porreca, Frank; Lai, Josephine; Hruby, Victor J.

Biological and Conformational Evaluation of Bifunctional Compounds for Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists Possessing Two Penicillamines

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2010-07-09

OAAI

Yamamoto, Takashi; Nair, Padma; Jacobsen, Neil E.; Kulkarni, Vinod; Davis, Peg; Ma, Shou-wu; Navratilova, Edita; Yamamura, Henry I.; Vanderah, Todd W.; Porreca, Frank; Lai, Josephine; Hruby, Victor J.

The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety

BIOORGANIC & MEDICINAL CHEMISTRY

IF3

2009-10-01

OAAI

Yamamoto, Takashi; Nair, Padma; Ma, Shou-Wu; Davis, Peg; Yamamura, Henry I.; Vanderah, Todd W.; Porreca, Frank; Lai, Josephine; Hruby, Victor J.

Sustained Morphine Treatment Augments Capsaicin-Evoked Calcitonin Gene-Related Peptide Release from Primary Sensory Neurons in a Protein Kinase A- and Raf-1-Dependent Manner

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2009-09-01

OAAI

Tumati, Suneeta; Yamamura, Henry I.; Vanderah, Todd W.; Roeske, William R.; Varga, Eva V.

Improving Metabolic Stability by Glycosylation: Bifunctional Peptide Derivatives That Are Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2009-07-22

OAAI

Yamamoto, Takashi; Nair, Padma; Jacobsen, Neil E.; Vagner, Josef; Kulkarni, Vinod; Davis, Peg; Ma, Shou-wu; Navratilova, Edita; Yamamura, Henry I.; Vanderah, Todd W.; Porreca, Frank; Lai, Josephine; Hruby, Victor J.

Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia 鞘内Raf-1-selective siRNA减轻持续吗啡介导的热痛觉过敏

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2008-12-01

OAAI

Tumati, Suneeta; Milnes, Tally Largent; Yamamura, Henry I.; Vanderah, Todd W.; Roeske, William R.; Varga, Eva V.

The Importance of Micelle-Bound States for the Bioactivities of Bifunctional Peptide Derivatives for δ/μ Opioid Receptor Agonists and Neurokinin 1 Receptor Antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-09-27

OAAI

Yamamoto, Takashi; Nair, Padma; Jacobsen, Neil E.; Davis, Peg; Ma, Shou-wu; Navratilova, Edita; Moye, Sharif; Lai, Josephine; Yamamura, Henry I.; Vanderah, Todd W.; Porreca, Frank; Hruby, Victor J.

Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2008-04-01

OAAI

Yue, Xu; Tumati, Suneeta; Navratilova, Edita; Stro, Dagmar; St John, Paul A.; Vanderah, Todd W.; Roeske, William R.; Yamamura, Henry I.; Varga, Eva V.

A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are δ/μ opioid receptor agonists and neurokinin 1 receptor antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2008-02-12

OAAI

Yamamoto, Takashi; Nair, Padma; Vagner, Josef; Largent-Milnes, Tally; Davis, Peg; Ma, Shou-wu; Navratilova, Edita; Moye, Sharif; Tumati, Suneeta; Lai, Josephine; Yamamura, Henry I.; Vanderah, Todd W.; Porreca, Frank; Hruby, Victor J.

Unique agonist-bound cannabinoid CB1 receptor conformations indicate agonist specificity in signaling

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2008-02-01

OAAI

Georgieva, Teodora; Devanathan, Savitha; Stropova, Dagmar; Park, Chad K.; Salamon, Zdzislaw; Tollin, Gordon; Hruby, Victor J.; Roeske, William R.; Yamamura, Henry I.; Varga, Eva

Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for δ/μ opioid receptor agonists and neurokinin-1 receptor antagonists

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2007-05-22

OAAI

Yamamoto, Takashi; Nair, Padma; Davis, Peg; Ma, Shou-wu; Navratilova, Edita; Moye, Sharif; Tumati, Suneeta; Lai, Josephine; Vanderah, Todd W.; Yamamura, Henry I.; Porreca, Frank; Hruby, Victor J.

Quantitative evaluation of human δ opioid receptor desensitization using the operational model of drug action

MOLECULAR PHARMACOLOGY

IF3

2007-05-01

PREAI

Navratilova, Edita; Waite, Sue; Stropova, Dagmar; Eaton, Miriam C.; Alves, Isabel D.; Hruby, Victor J.; Roeske, William R.; Yamamura, Henry I.; Varga, Eva V.

Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: Differentiation of agonists and antagonists

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2006-11-09

OAAI

Cai, Minying; Varga, Eva V.; Stankova, Magda; Mayorov, Alexander; Perry, Joseph W.; Yamamura, Henry I.; Trivedi, Dev; Hruby, Victor J.

New paradigms and tools in drug design for pain and addiction

AAPS JOURNAL

IF3.7

2006-09-01

OAAI

Hruby, Victor J.; Porreca, Frank; Yamamura, Henry I.; Tollin, Gordon; Agnes, Richard S.; Lee, Yeon Sun; Cai, Minying; Alves, Isabel; Cowell, Scott; Varga, Eva; Davis, Peg; Salamon, Zdzislaw; Roeske, William; Vanderah, Todd; Lai, Josephine

Chronic morphine-mediated adenylyl cyclase superactivation is attenuated by the Raf-1 inhibitor, GW5074

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2006-07-01

PREAI

Yue, Xu; Varga, Eva V.; Stropova, Dagmar; Vanderah, Todd W.; Yamamura, Henry I.; Roeske, William R.

Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2006-01-01

PREAI

Oki, T; Maruyama, S; Takagi, Y; Yamamura, HI; Yamada, S

Lipid bilayers on polyacrylamide brushes for inclusion of membrane proteins

LANGMUIR

IF3.9

2005-09-14

OAAI

Smith, EA; Coym, JW; Cowell, SM; Tokimoto, T; Hruby, VJ; Yamamura, HI; Wirth, MJ

Morphine promotes phosphorylation of the human δ-opioid receptor at serine 363

EUROPEAN JOURNAL OF PHARMACOLOGY

IF4.7

2005-09-01

PREAI

Navratilova, E; Eaton, MC; Stropova, D; Varga, EV; Vanderah, TW; Roeske, WR; Yamamura, HI

Glycopeptides related to β-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2005-03-24

PREAI

Dhanasekaran, M; Palian, MM; Alves, I; Yeomans, L; Keyari, CM; Davis, P; Bilsky, EJ; Egleton, RD; Yamamura, HI; Jacobsen, NE; Tollin, G; Hruby, VJ; Porreca, F; Polt, R

Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues

BIOPOLYMERS

IF3.2

2005-01-19

OAAI

Gu, XY; Ying, JF; Min, B; Cain, JP; Davis, P; Willey, P; Navratilova, E; Yamamura, HI; Porreca, F; Hruby, VJ

研究方向