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J

J. William Lown

机构信息待补充

50H指数
406论文数
9.4K被引数
收录论文 19
发表时间
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Bleomycin antibiotics and their role in cancer chemotherapy
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2008-02-29
err6
PREAI
errHuang, LR; Xie, Y; Lown, JW
err分享
err收藏
SYNTHESIS OF (4S)-METHYL AND (4R)-METHYL 2-AMINO-1-PYRROLINE-5-CARBOXYLATES AND THEIR APPLICATION TO THE PREPARATION OF (4S)-(+)-DIHYDROKIKUMYCIN-B AND (4R)-(-)-DIHYDROKIKUMYCIN-B
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2002-05-01
err31
PREAI
errLEE, M; LOWN, JW
err分享
err收藏
STRUCTURE ACTIVITY RELATIONSHIP OF NOVEL OLIGOPEPTIDE ANTIVIRAL AND ANTITUMOR AGENTS RELATED TO NETROPSIN AND DISTAMYCIN
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2002-05-01
err56
PREAI
errLOWN, JW; KROWICKI, K; BALZARINI, J; DECLERCQ, E
err分享
err收藏
ALKYLDINITROGEN SPECIES IMPLICATED IN THE CARCINOGENIC, MUTAGENIC, AND ANTICANCER ACTIVITIES OF N-NITROSO COMPOUNDS - CHARACTERIZATION BY N-15-NMR OF N-15-ENRICHED COMPOUNDS AND ANALYSIS OF DNA-BASE SITUSELECTIVITY BY ABINITIO CALCULATIONS
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2002-05-01
err55
PREAI
errLOWN, JW; CHAUHAN, SMS; KOGANTY, RR; SAPSE, AM
err分享
err收藏
CC-1065 FUNCTIONAL ANALOGS POSSESSING DIFFERENT ELECTRON-WITHDRAWING SUBSTITUENTS AND LEAVING GROUPS - SYNTHESIS, KINETICS, AND SEQUENCE SPECIFICITY OF REACTION WITH DNA AND BIOLOGICAL EVALUATION
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2002-05-01
err36
PREAI
errWANG, YQ; GUPTA, R; HUANG, LR; LOWN, JW
err分享
err收藏
CHARACTERIZATION OF A CPI-LEXITROPSIN CONJUGATE OLIGONUCLEOTIDE COVALENT COMPLEX BY H-1-NMR AND RESTRAINED MOLECULAR-DYNAMICS SIMULATION
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2002-05-01
err52
PREAI
errFREGEAU, NL; WANG, YQ; PON, RT; WYLIE, WA; LOWN, JW
err分享
err收藏
MOLECULAR RECOGNITION BETWEEN OLIGOPEPTIDES AND NUCLEIC-ACIDS - SEQUENCE-SPECIFIC BINDING OF THE NATURALLY-OCCURRING ANTIBIOTIC (4S)-(+)-ANTHELVENCIN-A AND ITS (4R)-(-) ENANTIOMER TO DEOXYRIBONUCLEIC ACIDS DEDUCED FROM H-1-NMR, FOOTPRINTING, AND THERMODYNAMIC DATAT
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2002-05-01
err48
PREAI
errLEE, M; SHEA, RG; HARTLEY, JA; KISSINGER, K; PON, RT; VESNAVER, G; BRESLAUER, KJ; DABROWIAK, JC; LOWN, JW
err分享
err收藏
STRUCTURE OF THE ADDUCT FORMED BETWEEN 3-AMINOCARBAZOLE AND THE APURINIC SITE OLIGONUCLEOTIDE MODEL D[TP(AP)PT]
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2002-05-01
err32
PREAI
errVASSEUR, JJ; RAYNER, B; IMBACH, JL; VERMA, S; MCCLOSKEY, JA; LEE, M; CHANG, DK; LOWN, JW
err分享
err收藏
SYNTHESIS OF CARBAZOMYCIN-B
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2002-05-01
err36
PREAI
errCLIVE, DLJ; ETKIN, N; JOSEPH, T; LOWN, JW
err分享
err收藏
MOLECULAR RECOGNITION BETWEEN OLIGOPEPTIDES AND NUCLEIC-ACIDS - INFLUENCE OF VANDERWAALS CONTACTS IN DETERMINING THE 3'-TERMINUS OF DNA-SEQUENCES READ BY MONOCATIONIC LEXITROPSINS
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2002-05-01
err66
PREAI
errLEE, M; KROWICKI, K; HARTLEY, JA; PON, RT; LOWN, JW
err分享
err收藏
DESIGN AND BINDING OF A DISTAMYCIN-A ANALOG TO D(CGCAAGTTGGC)BULLET-D(GCCAACTTGCG) - SYNTHESIS, NMR-STUDIES, AND IMPLICATIONS FOR THE DESIGN OF SEQUENCE-SPECIFIC MINOR GROOVE BINDING OLIGOPEPTIDES
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2002-05-01
err132
PREAI
errDWYER, TJ; GEIERSTANGER, BH; BATHINI, Y; LOWN, JW; WEMMER, DE
err分享
err收藏
DNA sequence recognition in the minor groove by crosslinked polyamides: The effect of N-terminal head group and linker length on binding affinity and specificity
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2001-12-26
err32
errOAAI
errO'Hare, CC; Mack, D; Tandon, M; Sharma, SK; Lown, JW; Kopka, ML; Dickerson, RE; Hartley, JA
err分享
err收藏
A general solution- and solid-phase synthetic procedure for incorporating three contiguous imidazole moieties into DNA sequence reading polyamides
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2001-01-11
err27
PREAI
errSharma, SK; Tandon, M; Lown, JW
err分享
err收藏
Design and synthesis of novel thiazole-containing cross-linked polyamides related to the antiviral antibiotic distamycin
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2000-01-27
err58
PREAI
errSharma, SK; Tandon, M; Lown, JW
err分享
err收藏
Synthesis of an unsymmetrical bis-lexitropsin-1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI) conjugate
errCHEMICAL COMMUNICATIONS
IF4.2
err1999-01-01
err20
PREAI
errJia, GF; Iida, H; Lown, JW
err分享
err收藏
Highly potent synthetic polyamides, bisdistamycins, and lexitropsins as inhibitors of human immunodeficiency virus type 1 integrase
errMOLECULAR PHARMACOLOGY
IF3
err1998-08-01
err81
PREAI
errNeamati, N; Mazumder, A; Sunder, S; Owen, JM; Tandon, M; Lown, JW; Pommier, Y
err分享
err收藏
Effects of bifunctional netropsin-related minor groove-binding ligands on mammalian type I DNA topoisomerase
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err1997-02-01
err15
PREAI
errWang, ZY; Zimmer, C; Lown, JW; Knippers, R
err分享
err收藏
Camptothecin and minor-groove binder hybrid molecules: Synthesis, inhibition of topoisomerase I, and anticancer cytotoxicity in vitro
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err1997-01-17
err31
PREAI
errZhao, RL; AlSaid, NH; Sternbach, DL; Lown, JW
err分享
err收藏
Photosensitization by anticancer agents .21. New perylene- and aminonaphthoquinones
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err1996-01-01
err39
PREAI
errDiwu, ZJJ; Haugland, RP; Liu, JX; Lown, JW; Miller, GG; Moore, RB; Brown, K; Tulip, J; McPhee, MS
err分享
err收藏

研究方向

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合作学者
合作期刊

Yves Pommier
H 指数: 138 · 论文数: 2.0K
J
Jan Balzarini
H 指数: 93 · 论文数: 1.1K
K
Kevin M. Brown
H 指数: 90 · 论文数: 490
R
Richard E. Dickerson
H 指数: 82 · 论文数: 227
D
David E. Wemmer
H 指数: 78 · 论文数: 404
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