Steven W. Baertschi - Publications, H-index & Citations

Steven W. Baertschi

Eli Lilly

29H指数

114论文数

2.8K被引数

收录论文 25

发表时间

Mass Balance in Pharmaceutical Stress Testing: A Review of Principles and Practical Applications

AAPS JOURNAL

IF3.7

2024-08-22

PREAI

Marden, Stacey; Campbell, John M.; Adams, Neal; Coelho, Ronan; Foti, Chris; Franca, Jucara Ribeiro; Hostyn, Steven; Huang, Zongyun; Ultramari, Mariah; Zelesky, Todd; Baertschi, Steven W.

In Silico Prediction of Pharmaceutical Degradation Pathways: A Benchmarking Study Using the Software Program Zeneth

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2024-02-19

OAAI

Hemingway, Rachel; Baertschi, Steven W.; Benstead, David; Campbell, John M.; Coombs, Maggie; Huang, Zongyun; Khalaf, Ryan; Ott, Martin A.; Ponting, David J.; Reid, Darren L.; Stevenson, Neil G.; Webb, Samuel J.; White, Angela; Zelesky, Todd

Pharmaceutical Forced Degradation (Stress Testing) Endpoints: A Scientific Rationale and Industry Perspective 药物强制降解 (压力测试) 终点: 科学原理和行业视角

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2023-12-01

PREAI

Zelesky, Todd; Baertschi, Steven W.; Foti, Chris; Allain, Leonardo R.; Hostyn, Steven; Franca, Jucara Ribeiro; Li, Yi; Marden, Stacey; Mohan, Shikhar; Ultramari, Mariah; Huang, Zongyun; Adams, Neal; Campbell, John M.; Jansen, Patrick J.; Kotoni, Dorina; Laue, Christian

Assessing the Relevance of Solution Phase Stress Testing of Solid Dosage Form Drug Products: A Cross-Industry Benchmarking Study

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2022-02-01

PREAI

Campbell, John M.; Foti, Chris; Wang, Chloe; Adams, Neal; Allain, Leonardo R.; Araujo, Gabriela; Azevedo, Renan; Franca, Jucara Ribeiro; Hicks, Simon R.; Hostyn, Steven; Jansen, Patrick J.; Kotoni, Dorina; Kuemmell, Andreas; Marden, Stacey; Rullo, Gregory; Santos, Ana Claudia O.; Sluggett, Gregory W.; Zelesky, Todd; Baertschi, Steven W.

Degradation Rate Observations as a Function of Drug Load in Solid-State Drug Products

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2019-05-01

PREAI

Baertschi, Steven W.; Dill, Allison L.; Kramer, Timothy T.; Scrivens, Garry; Suruzhon, Miroslav

Impurity investigations by phases of drug and product development

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

IF12

2018-04-01

PREAI

Olsen, Bernard A.; Sreedhara, Alavattam; Baertschi, Steven W.

Artifactual degradation of secondary amine-containing drugs during accelerated stability testing when saturated sodium nitrite solutions are used for humidity control

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2018-02-01

PREAI

Sluggett, Gregory W.; Zelesky, Todd; Hetrick, Evan M.; Babayan, Yelizaveta; Baertschi, Steven W.

Mechanistic Studies of the N-formylation of Edivoxetine, a Secondary Amine-Containing Drug, in a Solid Oral Dosage Form

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2017-05-01

PREAI

Hyzer, Cherokee S. Hoaglund; Williamson, Michele L.; Jansen, Patrick J.; Kopach, Michael E.; Scherer, R. Brian; Baertschi, Steven W.

Determination of the Degradation Chemistry of the Antitumor Agent Pemetrexed Disodium

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2016-11-01

PREAI

Jansen, Patrick J.; Smith, William K.; Baertschi, Steven W.; Dorman, Douglas E.; Kemp, Craig A. J.; McCune, Karen A.

Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 3. Oral Drug Products

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2016-05-01

PREAI

Allain, Leonardo; Baertschi, Steven W.; Clapham, David; Foti, Chris; Lantaff, Wendy M.; Reed, Robert A.; Templeton, Allen C.; Tonnesen, Hanne Hjorth

Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 2: Topical Drug Product

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2015-09-01

OAAI

Baertschi, Steven W.; Clapham, David; Foti, Chris; Kleinman, Mark H.; Kristensen, Solveig; Reed, Robert A.; Templeton, Allen C.; Tonnesen, Hanne Hjorth

Strategies To Address Mutagenic Impurities Derived from Degradation in Drug Substances and Drug Products

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2015-06-10

PREAI

Kleinman, Mark H.; Elder, David; Teasdale, Andrew; Mowery, Mark D.; McKeown, Alan P.; Baertschi, Steven W.

Assessing the Risk of Formation of Potential Genotoxic Degradation Products in a Small-Molecule Kinase Inhibitor Drug Substance and Drug Product

ORGANIC PROCESS RESEARCH & DEVELOPMENT

IF3.5

2015-06-02

PREAI

Strege, Mark A.; Osborne, Linda M.; Hetrick, Evan M.; Dill, Allison L.; Jansen, Patrick J.; Draper, Jerry R.; Montgomery, Robert M.; Buser, Jonas Y.; Pack, Brian W.; Smitka, Tim A.; Baertschi, Steven W.

Investigation of the Mechanism of Racemization of Litronesib in Aqueous Solution: Unexpected Base-Catalyzed Inversion of a Fully Substituted Carbon Chiral Center

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2014-09-01

OAAI

Baertschi, Steven W.; Jansen, Patrick J.; Montgomery, Robert M.; Smith, William K.; Draper, Jerry R.; Myers, David P.; Houghton, Peter G.; Sharp, V. Scott; Guisbert, Andrea L.; Zhuang, Hong; Watkins, Michael A.; Stephenson, Gregory A.; Harris, Thomas M.

Recent Trends in Product Development and Regulatory Issues on Impurities in Active Pharmaceutical Ingredient (API) and Drug Products. Part 2: Safety Considerations of Impurities in Pharmaceutical Products and Surveying the Impurity Landscape

AAPS PHARMSCITECH

IF4

2013-12-21

OAAI

Alsante, Karen M.; Huynh-Ba, Kim C.; Baertschi, Steven W.; Reed, Robert A.; Landis, Margaret S.; Furness, Scott; Olsen, Bernard; Mowery, Mark; Russo, Karen; Iser, Robert; Stephenson, Gregory A.; Jansen, Patrick

On-column nitrosation of amines observed in liquid chromatography impurity separations employing ammonium hydroxide and acetonitrile as mobile phase 在使用氢氧化铵和乙腈作为流动相的液相色谱杂质分离中观察到的胺的柱上亚硝化

JOURNAL OF CHROMATOGRAPHY A

IF4

2013-12-01

PREAI

Myers, David P.; Hetrick, Evan M.; Liang, Zhongming; Hadden, Chad E.; Bandy, Steven; Kemp, Craig A.; Harris, Thomas M.; Baertschi, Steven W.

Recent Trends in Product Development and Regulatory Issues on Impurities in Active Pharmaceutical Ingredient (API) and Drug Products. Part 1: Predicting Degradation Related Impurities and Impurity Considerations for Pharmaceutical Dosage Forms

AAPS PHARMSCITECH

IF4

2013-11-27

OAAI

Alsante, Karen M.; Huynh-Ba, Kim; Baertschi, Steven W.; Reed, Robert A.; Landis, Margaret S.; Kleinman, Mark H.; Foti, Christopher; Rao, Venkatramana M.; Meers, Paul; Abend, Andreas; Reynolds, Daniel W.; Joshi, Biren K.

Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 1: Drug Products Administered by Injection

JOURNAL OF PHARMACEUTICAL SCIENCES

IF3.8

2013-11-01

PREAI

Baertschi, Steven W.; Clapham, David; Foti, Chris; Jansen, Patrick J.; Kristensen, Solveig; Reed, Robert A.; Templeton, Allen C.; Tonnesen, Hanne Hjorth

Assessing mass balance in pharmaceutical drug products: New insights into an old topic

TRAC-TRENDS IN ANALYTICAL CHEMISTRY

IF12

2013-09-01

PREAI

Baertschi, Steven W.; Pack, Brian W.; Hyzer, Cherokee S. Hoaglund; Nussbaum, Mark A.

Artifactual formylation of the secondary amine of duloxetine hydrochloride by acetonitrile in the presence of titanium dioxide: Implications for HPLC method development

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

IF3.1

2010-11-01

PREAI

Skibic, M. J.; King, L. A.; Khan, M.; Fox, P. J.; Winger, B. E.; Baertschi, S. W.

研究方向