未登录 Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells Li, Ruidong; Liclican, Albert; Xu, Yili; Pitts, Jared; Niu, Congrong; Zhang, Jingyu; Kim, Cynthia; Zhao, Xiaofeng; Soohoo, Daniel; Babusis, Darius; Yue, Qin; Ma, Bin; Murray, Bernard P.; Subramanian, Raju; Xie, Xuping; Zou, Jing; Bilello, John P.; Li, Li; Schultz, Brian E.; Sakowicz, Roman; Smith, Bill J.; Shi, Pei-Yong; Murakami, Eisuke; Feng, Joy Y. 分享 收藏
Species-Specific Urothelial Toxicity With an Anti-HIV Noncatalytic Site Integrase Inhibitor (NCINI) Is Related to Unusual pH-Dependent Physicochemical Changes Roberts, Ruth A.; Campbell, Richard A.; Sikakana, Phumzile; Sadler, Claire; Osier, Mark; Xu, Yili; Feng, Joy Y.; Mitchell, Michael; Sakowicz, Roman; Chester, Anne; Paoli, Eric; Wang, Jianhong; Burns-Naas, Leigh Ann 分享 收藏
Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent Xu, Yili; Barauskas, Ona; Kim, Cynthia; Babusis, Darius; Murakami, Eisuke; Kornyeyev, Dmytro; Lee, Gary; Stepan, George; Perron, Michel; Bannister, Roy; Schultz, Brian E.; Sakowicz, Roman; Porter, Danielle; Cihlar, Tomas; Feng, Joy Y. 分享 收藏
Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9 Appleby, Todd C.; Greenstein, Andrew E.; Hung, Magdeleine; Liclican, Albert; Velasquez, Maile; Villasenor, Armando G.; Wang, Ruth; Wong, Melanie H.; Liu, Xiaohong; Papalia, Giuseppe A.; Schultz, Brian E.; Sakowicz, Roman; Smith, Victoria; Kwon, Hyock Joo 分享 收藏
Role of Mitochondrial RNA Polymerase in the Toxicity of Nucleotide Inhibitors of Hepatitis C Virus Feng, Joy Y.; Xu, Yili; Barauskas, Ona; Perry, Jason K.; Ahmadyar, Shekeba; Stepan, George; Yu, Helen; Babusis, Darius; Park, Yeojin; McCutcheon, Krista; Perron, Michel; Schultz, Brian E.; Sakowicz, Roman; Ray, Adrian S. 分享 收藏
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GS-5806 Inhibits Pre- to Postfusion Conformational Changes of the Respiratory Syncytial Virus Fusion Protein Samuel, Dharmaraj; Xing, Weimei; Niedziela-Majka, Anita; Wong, Jinny S.; Hung, Magdeleine; Brendza, Katherine M.; Perron, Michel; Jordan, Robert; Sperandio, David; Liu, Xiaohong; Mackman, Richard; Sakowicz, Roman 分享 收藏
New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action Tsiang, Manuel; Jones, Gregg S.; Niedziela-Majka, Anita; Kan, Elaine; Lansdon, Eric B.; Huang, Wayne; Hung, Magdeleine; Samuel, Dharmaraj; Novikov, Nikolai; Xu, Yili; Mitchell, Michael; Guo, Hongyan; Babaoglu, Kerim; Liu, Xiaohong; Geleziunas, Romas; Sakowicz, Roman 分享 收藏
Lipid Sensing Apolipoprotein A-I for Novel High-Throughput Lipidation Assays Niedziela-Majka, Anita; Lad, Latesh; Chishom, Jeffrey W.; Lagpacan, Leanna; Schwartz, Karen; Hung, Magdeleine; Jin, Debi; Fung, Wanchi; Brendza, Katherine M.; Liu, Xioahong; Pagratis, Nikos; Sakowicz, Roman 分享 收藏
Insight into the molecular mechanism of the multitasking kinesin-8 motor Peters, Carsten; Brejc, Katjusa; Belmont, Lisa; Bodey, Andrew J.; Lee, Yan; Yu, Ming; Guo, Jun; Sakowicz, Roman; Hartman, James; Moores, Carolyn A. 分享 收藏
Antitumor activity of an allosteric inhibitor of centromere-associated protein-E 着丝粒相关蛋白-E变构抑制剂的抗肿瘤活性 Wood, Kenneth W.; Lad, Latesh; Luo, Lusong; Qian, Xiangping; Knight, Steven D.; Nevins, Neysa; Brejc, Katjusa; Sutton, David; Gilmartin, Aidan G.; Chua, Penelope R.; Desai, Radhika; Schauer, Stephen P.; McNulty, Dean E.; Annan, Roland S.; Belmont, Lisa D.; Garcia, Carlos; Lee, Yan; Diamond, Melody A.; Faucette, Leo F.; Giardiniere, Michele; Zhang, ShuYun; Sun, Chiu-Mei; Vidal, Justin D.; Lichtsteiner, Serge; Cornwell, William D.; Greshock, Joel D.; Wooster, Richard F.; Finer, Jeffrey T.; Copeland, Robert A.; Huang, Pearl S.; Morgans, David J., Jr.; Dhanak, Dashyant; Bergnes, Gustave; Sakowicz, Roman; Jackson, Jeffrey R. 分享 收藏
Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295 Qian, Xiangping; McDonald, Andrew; Zhou, Han-Jie; Adams, Nicholas D.; Parrish, Cynthia A.; Duffy, Kevin J.; Fitch, Duke M.; Tedesco, Rosanna; Ashcraft, Luke W.; Yao, Bing; Jiang, Hong; Huang, Jennifer K.; Marin, Melchor V.; Aroyan, Carrie E.; Wang, Jianchao; Ahmed, Seyed; Burgess, Joelle L.; Chaudhari, Amita M.; Donatelli, Carla A.; Darcy, Michael G.; Ridgers, Lance H.; Newlander, Ken A.; Schmidt, Stanley J.; Chai, Deping; Colon, Mariela; Zimmerman, Michael N.; Lad, Latesh; Sakowicz, Roman; Schauer, Stephen; Belmont, Lisa; Baliga, Ramesh; Pierce, Daniel W.; Finer, Jeffrey T.; Wang, Zhengping; Morgan, Bradley P.; Morgans, David J., Jr.; Auger, Kurt R.; Sung, Chiu-Mei; Carson, Jeff D.; Luo, Lusong; Hugger, Erin D.; Copeland, Robert A.; Sutton, David; Elliott, John D.; Jackson, Jeffrey R.; Wood, Kenneth W.; Dhanak, Dashyant; Bergnes, Gustave; Knight, Steven D. 分享 收藏
The Molecular Mechanism of the Multi-Tasking Kinesin-8 Motor Peters, Carsten; Brejc, Katjusa; Belmont, Lisa; Bodey, Andrew; Lee, Yan; Yu, Ming; Ramchandani, Shyam; Guo, Jun; Lichtsteiner, Serge; Wood, Kenneth; Sakowicz, Roman; Hartman, Jim; Moores, Carolyn 分享 收藏
Nucleic Acid Translocation By Hepatitis C Virus Helicase NS3h Is Dependent on Sugar and Base Moieties Fischer, Christopher J.; Khaki, Ali R.; Field, Cassandra; Malik, Shuja; Wang, Ruth; Niedziela-Majka, Anita; Leavitt, Stephanie; Hung, Magdeleine; Sakowicz, Roman; Brendza, Katherine M. 分享 收藏
Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex Tsiang, Manuel; Jones, Gregg S.; Hung, Magdeleine; Mukund, Susmith; Han, Bin; Liu, Xiaohong; Babaoglu, Kerim; Lansdon, Eric; Chen, Xiaowu; Todd, Jacob; Cai, Terrence; Pagratis, Nikos; Sakowicz, Roman; Geleziunas, Romas 分享 收藏
ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism Luo, Lusong; Parrish, Cynthia A.; Nevins, Neysa; McNulty, Dean E.; Chaudhari, Amita M.; Carson, Jeffery D.; Sudakin, Valery; Shaw, Antony N.; Lehr, Ruth; Zhao, Huizhen; Sweitzer, Sharon; Lad, Latesh; Wood, Kenneth W.; Sakowicz, Roman; Annan, Roland S.; Huang, Pearl S.; Jackson, Jeffrey R.; Dhanak, Dashyant; Copeland, Robert A.; Auger, Kurt R. 分享 收藏
Novel ATP-competitive kinesin spindle protein inhibitors Parrish, Cynthia A.; Adams, Nicholas D.; Auger, Kurt R.; Burgess, Joelle L.; Carson, Jeffrey D.; Chaudhari, Amita M.; Copeland, Robert A.; Diamond, Melody A.; Donatelli, Carla A.; Duffy, Kevin J.; Faucette, Leo F.; Finer, Jeffrey T.; Huffman, William F.; Hugger, Erin D.; Jackson, Jeffrey R.; Knight, Steven D.; Luo, Lusong; Moore, Michael L.; Newlander, Ken A.; Ridgers, Lance H.; Sakowicz, Roman; Shaw, Antony N.; Sung, Chiu-Mei M.; Sutton, David; Wood, Kenneth W.; Zhang, Shu-Yun; Zimmerman, Michael N.; Dhanak, Dashyant 分享 收藏
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In vitro and in vivo characterization of CK-1827452, a selective cardiac myosin activator Anderson, Robert L.; Sueoka, Sandra H.; Lee, Kenneth H.; Rodriguez, Hector M.; Kawas, Raja F.; Godinez, Guillermo; Morgan, Bradley P.; Sakowicz, Roman; Morgans, David J.; Malik, Fady; Elias, Kathleen A. 分享 收藏
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