未登录

N

N D Marchenko

state university of new york (suny) system

H指数:15

被引数:2,271

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis (vol 20, 898, 2013)

CELL DEATH AND DIFFERENTIATION

IF15.4

2024-09-100

PRE

The role of ubiquitination in the direct mitochondrial death program of p53

IF3.4

2014-10-2873

OAAI

A gain-of-function mutant p53-HSF1 feed forward circuit governs adaptation of cancer cells to proteotoxic stress

功能获得突变p53-HSF1前馈电路控制癌细胞对蛋白毒性应激的适应

CELL DEATH & DISEASE

IF9.6

2014-04-2481

OAAI

p63 is a prosurvival factor in the adult mammary gland during post-lactational involution, affecting PI-MECs and ErbB2 tumorigenesis

p63是催乳后退化过程中成年乳腺的促生存因子，影响pi-mecs和ErbB2肿瘤发生

CELL DEATH AND DIFFERENTIATION

IF15.4

2014-01-1740

OA

HER2/ErbB2 activates HSF1 and thereby controls HSP90 clients including MIF in HER2-overexpressing breast cancer

CELL DEATH & DISEASE

IF9.6

2014-01-0273

OAAI

Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis

CELL DEATH AND DIFFERENTIATION

IF15.4

2013-03-29244

OA

SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis

SAHA通过抑制HDAC6-Hsp90伴侣轴使突变型p53不稳定，从而在突变型p53癌细胞中显示出优先的细胞毒性

CELL DEATH AND DIFFERENTIATION

IF15.4

2011-06-03308

OAAI

Blockade of Hsp90 by 17AAG antagonizes MDMX and synergizes with Nutlin to induce p53-mediated apoptosis in solid tumors

CELL DEATH & DISEASE

IF9.6

2011-05-1257

OAAI

BclxL Changes Conformation upon Binding to Wild-type but Not Mutant p53 DNA Binding Domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2010-01-0178

OAAI

Stress-mediated nuclear stabilization of p53 is regulated by ubiquitination and importin-α3 binding

p53的应激介导的核稳定受泛素化和importin-α3结合的调节

CELL DEATH AND DIFFERENTIATION

IF15.4

2009-11-20109

OAAI

Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma

野生型p53的超泛素化有助于神经母细胞瘤的细胞质隔离

CELL DEATH AND DIFFERENTIATION

IF15.4

2007-03-2347

OAAI

Monoubiquitylation promotes mitochondrial p53 translocation

IF8.3

2007-02-01294

OAAI

p53 and Nur77/TR3 - transcription factors that directly target mitochondria for cell death induction

IF7.3

2006-08-07250

PREAI

WT p53, but not tumor-derived mutants, bind to Bcl2 via the DNA binding domain and induce mitochondrial permeabilization

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2006-03-01254

PREAI