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Thomas K. H. Chang

University of British Columbia

64H指数
330论文数
1.5W被引数
收录论文 35
发表时间
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A NOVEL THERAPEUTICALLY ACTIVE ANTITNFR2 AGONISTIC ANTIBODY PROMOTES TREG PROLIFERATION AND INDUCTION OFTREG FUNCTIONAL MARKERS一种新型的具有治疗活性的抗TNFR2激动性抗体促进Treg增殖并诱导Treg功能标志物
errANNALS OF THE RHEUMATIC DISEASES
IF20.6
err2024-06-01
err1
PREAI
errMiyazaki, T.; Maiti, M.; Amit, I.; Hamel, D.; Wu, Q.; Pena, R.; Brendza, K.; Chang, T.; Guo, V.; Kivimae, S.; Ofran, Y.; Zalevsky, J.
err分享
err收藏
NKTR-255, a novel polymer-conjugated rhIL-15 with potent antitumor efficacy
errJOURNAL FOR IMMUNOTHERAPY OF CANCER
IF10.6
err2021-05-17
err39
errOAAI
errMiyazaki, Takahiro; Maiti, Mekhala; Hennessy, Marlene; Chang, Thomas; Kuo, Peiwen; Addepalli, Murali; Obalapur, Palakshi; Sheibani, Sara; Wilczek, Joanna; Pena, Rhoneil; Quach, Phi; Cetz, Janet; Moffett, Andrew; Tang, Yinyan; Kirk, Peter; Huang, Jicai; Sheng, Dawei; Zhang, Ping; Rubas, Werner; Madakamutil, Loui; Kivimae, Saul; Zalevsky, Jonathan
err分享
err收藏
The xenobiotic sensing pregnane X receptor regulates tissue damage and inflammation triggered by C difficile toxins
errFASEB JOURNAL
IF4.2
err2019-12-17
err17
errOAAI
errErickson, Sarah L.; Alston, Laurie; Nieves, Kristoff; Chang, Thomas K. H.; Mani, Sridhar; Flannigan, Kyle L.; Hirota, Simon A.
err分享
err收藏
Pregnane X Receptor Activation Triggers Rapid ATP Release in Primed Macrophages That Mediates NLRP3 Inflammasome Activation
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2019-07-01
err22
errOAAI
errHudson, Grace; Flannigan, Kyle L.; Venu, Vivek Krishna Pulakazhi; Alston, Laurie; Sandal, Christina F.; MacDonald, Justin A.; Muruve, Daniel A.; Chang, Thomas K. H.; Mani, Sridhar; Hirota, Simon A.
err分享
err收藏
Comparative analysis of ginsenosides in human glucocorticoid receptor binding, transactivation, and transrepression
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2017-11-01
err16
PREAI
errHu, Catherine; Lau, Aik Jiang; Wang, Ruiqi; Chang, Thomas K. H.
err分享
err收藏
Negative Regulation of Human Pregnane X Receptor by MicroRNA-18a-5p: Evidence for Suppression of MicroRNA-18a-5p Expression by Rifampin and Rilpivirine
errMOLECULAR PHARMACOLOGY
IF3
err2017-07-01
err13
errOAAI
errSharma, Devinder; Turkistani, Abdullah A.; Chang, Wenjun; Hu, Catherine; Xu, Zhaoming; Chang, Thomas K. H.
err分享
err收藏
Mechanistic modeling of a new kinetically-controlled CD122 agonist for cancer immunotherapy: NKTR-214 pharmacokinetics, pharmacodynamics, and receptor pharmacology
errCANCER RESEARCH
IF16.6
err2017-07-01
err0
PREAI
errKhalili, Samira; Odinecs, Aleksandrs; Charych, Deborah H.; Dixit, Vidula; Kirk, Peter; Chang, Thomas; Langowski, John; Rubas, Werner; Doberstein, Steve; Zalevsky, Jonathan; Eldon, Michael A.; Hoch, Ute
err分享
err收藏
Constitutive androstane receptor regulates the intestinal mucosal response to injury
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2017-04-19
err38
errOAAI
errHudson, Grace M.; Flannigan, Kyle L.; Erickson, Sarah L.; Vicentini, Fernando A.; Zamponi, Alexandra; Hirota, Christina L.; Alston, Laurie; Altier, Christophe; Ghosh, Subrata; Rioux, Kevin P.; Mani, Sridhar; Chang, Thomas K.; Hirota, Simon A.
err分享
err收藏
Pregnane X Receptor Activation Attenuates Inflammation-Associated Intestinal Epithelial Barrier Dysfunction by Inhibiting Cytokine-Induced Myosin Light-Chain Kinase Expression and c-Jun N-Terminal Kinase 1/2 Activation
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2016-10-01
err64
errOAAI
errGarg, Aditya; Zhao, Angela; Erickson, Sarah L.; Mukherjee, Subhajit; Lau, Aik Jiang; Alston, Laurie; Chang, Thomas K. H.; Mani, Sridhar; Hirota, Simon A.
err分享
err收藏
NKTR-214, an Engineered Cytokine with Biased IL2 Receptor Binding, Increased Tumor Exposure, and Marked Efficacy in Mouse Tumor Models
errCLINICAL CANCER RESEARCH
IF10.2
err2016-01-31
err363
errOAAI
errCharych, Deborah H.; Hoch, Ute; Langowski, John L.; Lee, Steve R.; Addepalli, Murali K.; Kirk, Peter B.; Sheng, Dawei; Liu, Xiaofeng; Sims, Paul W.; VanderVeen, Laurie A.; Ali, Cherie F.; Chang, Thomas K.; Konakova, Marina; Pena, Rhoneil L.; Kanhere, Rupesh S.; Kirksey, Yolanda M.; Ji, Chunmei; Wang, Yujun; Huang, Jicai; Sweeney, Theresa D.; Kantak, Seema S.; Doberstein, Stephen K.
err分享
err收藏
3-Hydroxyflavone and structural analogues differentially activate pregnane X receptor: Implication for inflammatory bowel disease
errPHARMACOLOGICAL RESEARCH
IF10.5
err2015-10-01
err21
PREAI
errLau, Aik Jiang; Chang, Thomas K. H.
err分享
err收藏
Differential activation of human constitutive androstane receptor and its SV23 and SV24 splice variants by rilpivirine and etravirine
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2015-02-10
err9
errOAAI
errSharma, Devinder; Lau, Aik Jiang; Sherman, Matthew A.; Chang, Thomas K. H.
err分享
err收藏
Fetal bovine serum and human constitutive androstane receptor: Evidence for activation of the SV23 splice variant by artemisinin, artemether, and arteether in a serum-free cell culture system
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2014-06-01
err11
PREAI
errLau, Aik Jiang; Chang, Thomas K. H.
err分享
err收藏
Localization of Cytochrome P450 and Related Enzymes in Adult Rat Testis and Downregulation by Estradiol and Bisphenol A
errTOXICOLOGICAL SCIENCES
IF4.1
err2014-04-20
err20
errOAAI
errGilibili, Ravindranath Reddy; Vogl, A. Wayne; Chang, Thomas K. H.; Bandiera, Stelvio M.
err分享
err收藏
Modulation of cytokine activity through advanced polymer conjugation
errCYTOKINE
IF3.7
err2013-09-01
err0
PREAI
errKirk, Peter; Addepalli, Murali; Ali, Cherie; Chang, Thomas; Huang, Jicai; Lee, Steve; Sims, Paul; VanderVeen, Laurie; Wang, Yujun; Charych, Deborah
err分享
err收藏
Indirect activation of the SV23 and SV24 splice variants of human constitutive androstane receptor: analysis with 3-hydroxyflavone and its analogues
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2013-08-27
err13
errOAAI
errLau, Aik Jiang; Chang, Thomas K. H.
err分享
err收藏
Agonism of human pregnane X receptor by rilpivirine and etravirine: Comparison with first generation non-nucleoside reverse transcriptase inhibitors
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2013-06-01
err34
PREAI
errSharma, Devinder; Lau, Aik Jiang; Sherman, Matthew A.; Chang, Thomas K. H.
err分享
err收藏
Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2012-11-01
err27
PREAI
errSurendradoss, Jayakumar; Chang, Thomas K. H.; Abbott, Frank S.
err分享
err收藏
Isoform-Selective Activation of Human Constitutive Androstane Receptor by Ginkgo biloba Extract: Functional Analysis of the SV23, SV24, and SV25 Splice Variants
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2011-11-01
err14
PREAI
errLau, Aik Jiang; Yang, Guixiang; Chang, Thomas K. H.
err分享
err收藏
Estradiol-mediated suppression of CYP1B1 expression in mouse MA-10 Leydig cells is independent of protein kinase A and estrogen receptor
errMOLECULAR AND CELLULAR BIOCHEMISTRY
IF3.7
err2011-07-23
err5
PREAI
errDeb, Subrata; Tai, Jenny K.; Leung, Grace S.; Chang, Thomas K. H.; Bandiera, Stelvio M.
err分享
err收藏

研究方向

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