Richard A. Roth - Publications, H-index & Citations

Richard A. Roth

机构信息待补充

73H指数

226论文数

2.1W被引数

收录论文 31

发表时间

PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2007-07-01

515

PREAI

Wang, Lifu; Harris, Thurl E.; Roth, Richard A.; Lawrence, John C., Jr.

Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation 蛋白激酶B/Akt磷酸化PDE3A及其在哺乳动物卵母细胞成熟中的作用

EMBO JOURNAL

IF8.3

2006-11-23

102

OAAI

Han, Seung Jin; Vaccari, Sergio; Nedachi, Taku; Andersen, Carsten B.; Kovacina, Kristina S.; Roth, Richard A.; Conti, Marco

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2 Akt1抑制乳腺癌细胞侵袭的机制揭示了TSC2的成瘤作用

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2006-03-07

185

OAAI

Liu, H; Radisky, DC; Nelson, CM; Zhang, H; Fata, JE; Roth, RA; Bissell, MJ

Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt activity

CLINICAL CANCER RESEARCH

IF10.2

2004-12-07

377

PREAI

DeGraffenried, LA; Friedrichs, WE; Russell, DH; Donzis, EJ; Middleton, AK; Silva, JM; Roth, RA; Hidalgo, M

Modulation of human insulin receptor substrate-1 tyrosine phosphorylation by protein kinase Cδ 蛋白激酶c δ 对人胰岛素受体底物1酪氨酸磷酸化的调节

BIOCHEMICAL JOURNAL

IF4.3

2004-02-15

OAAI

Greene, MW; Morrice, N; Garofalo, RS; Roth, RA

Inorganic polyphosphate stimulates mammalian TOR, a kinase involved in the proliferation of mammary cancer cells

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2003-09-11

178

OAAI

Wang, LH; Fraley, CD; Faridi, J; Kornberg, A; Roth, RA

Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by serine 312 phosphorylation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2003-03-01

188

OAAI

Greene, MW; Sakaue, H; Wang, LH; Alessi, DR; Roth, RA

Identification of a proline-rich Akt substrate as a 14-3-3 binding partner

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2003-03-01

349

OAAI

Kovacina, KS; Park, GY; Bae, SS; Guzzetta, AW; Schaefer, E; Birnbaum, MJ; Roth, RA

Akt modulates STAT3-mediated gene expression through a FKHR (FOXO1a)-dependent mechanism

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2003-02-01

OAAI

Kortylewski, M; Feld, F; Krüger, KD; Bahrenberg, G; Roth, RA; Joost, HG; Heinrich, PC; Behrmann, I; Barthel, A

Protein kinase B/Akt is essential for the insulin- but not progesterone-stimulated resumption of meiosis in Xenopus oocytes

BIOCHEMICAL JOURNAL

IF4.3

2003-01-15

OAAI

Andersen, CB; Sakaue, H; Nedachi, T; Kovacina, KS; Clayberger, C; Conti, M; Roth, RA

Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2001-11-01

340

OAAI

Greenberg, AS; Shen, WJ; Muliro, K; Patel, S; Souza, SC; Roth, RA; Kraemer, FB

Ligand-dependent interaction of estrogen receptor-α with members of the forkhead transcription factor family

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2001-09-01

140

PREAI

Schuur, ER; Loktev, AV; Sharma, M; Sun, ZJ; Roth, RA; Weigel, RJ

Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling

THYROID

IF6.7

2001-04-01

PREAI

Saito, J; Kohn, AD; Roth, RA; Noguchi, Y; Tatsumo, I; Hirai, A; Suzuki, K; Kohn, LD; Saji, M; Ringel, MD

The insulin receptor substrate (IRS)-1 pleckstrin homology domain functions in downstream signaling

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2001-03-01

OAAI

Vainshtein, I; Kovacina, KS; Roth, RA

The MMAC1 tumor suppressor phosphatase inhibits phospholipase C and integrin-linked kinase-activity

ONCOGENE

IF7.3

2000-01-20

PREAI

Morimoto, AM; Tomlinson, MG; Nakatani, K; Bolen, JB; Roth, RA; Herbst, R

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

1999-07-01

523

OAAI

Nakatani, K; Thompson, DA; Barthel, A; Sakaue, H; Liu, W; Weigel, RJ; Roth, RA

Regulation of GLUT1 gene transcription by the serine threonine kinase Akt1

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

1999-07-01

323

PREAI

Barthel, A; Okino, ST; Liao, JF; Nakatani, K; Li, JP; Whitlock, JP; Roth, RA

The role of glycogen synthase kinase 3β in insulin-stimulated glucose metabolism

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

1999-06-01

200

OAAI

Summers, SA; Kao, AW; Kohn, AD; Backus, GS; Roth, RA; Pessin, JE; Birnbaum, MJ

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

1999-04-01

212

OAAI

Li, JP; DeFea, K; Roth, RA

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

1998-10-01

130

OAAI

Liao, JF; Barthel, A; Nakatani, K; Roth, RA

研究方向