未登录Trial in progress: Phase 1 dose escalation study of T-1101, a first-in-class oral Hec1/Nek2 inhibitor, in patients with advanced refractory solid tumors
Su, Wu-Chou; Bai, Li-Yuan; Hsiao, Hui-Hua; Shiah, Her-Shyong; Yeh, Yu-Min; Chen, Shang-Hung; Wu, Shang-Yin; Wang, Hui-Ching; Tsai, Hui-Jen; Chang, Kwang-Yu; Tsai, Jui-Hung; Lee, Chun-Hui; Lee, Chieh Hua; Chao, Yu-Sheng; Chen, Li-Tzong .png)
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收藏DBPR108, a novel dipeptidyl peptidase-4 inhibitor with antihyperglycemic activityDBPR108，一种具有抗高血糖活性的新型二肽基peptidase-4抑制剂Yeh, Kai-Chia; Yeh, Teng-Kuang; Huang, Chung-Yu; Hu, Chih-Bo; Wang, Min-Hsien; Huang, Yu-Wen; Chou, Ling-Hui; Ho, Hsuan-Hui; Song, Jen-Shin; Hsu, Tsu; Jiaang, Weir-Torn; Chao, Yu-Sheng; Chen, Chiung-Tong 分享 收藏 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapyHsu, Chia-Yu; Chen, Yun-Yu; Lo, Chen-Fu; Chiu, Tai-Yu; Chen, Ching-Ping; Huang, Chen-Lung; Huang, Chung-Yu; Wang, Min-Hsien; Chao, Yu-Sheng; Shih, Joe C.; Yeh, Teng-Kuang; Tsou, Lun K.; Chen, Chiung-Tong 分享 收藏 A novel, potent, and orally bioavailable thiazole HCV NS5A inhibitor for the treatment of hepatitis C virusYeh, Teng-Kuang; Kang, Iou-Jiun; Hsu, Tsu-An; Lee, Yen-Chun; Lee, Chung-Chi; Hsu, Sheng-Ju; Tian, Ya-Wen; Yang, Hui-Yun; Chen, Chiung-Tong; Chao, Yu-Sheng; Yueh, Andrew; Chern, Jyh-Haur 分享 收藏 Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2Yuan, Mao-Chia; Yeh, Teng-Kuang; Chen, Chiung-Tong; Song, Jen-Shin; Huang, Yu-Chen; Hsieh, Tsung-Chih; Huang, Chung-Yu; Huang, Yu-Ling; Wang, Min-Hsien; Wu, Szu-Huei; Yao, Chun-Hsu; Chao, Yu-Sheng; Lee, Jinq-Chyi 分享 收藏 分享 收藏 A Potent, Selective, and Orally Bioavailable HCV NS5A Inhibitor for Treatment of Hepatitis C Virus: (S)-1-((R)-2-(Cyclopropanecarboxamido)-2-phenylacetyl)-N-(4-phenylthiazol-2-yl)pyrrolidine-2-carboxamideKang, Iou-Jiun; Hsu, Sheng-Ju; Yang, Hui-Yun; Yeh, Teng-Kuan; Lee, Chung-Chi; Lee, Yen-Chun; Tian, Ya-Wen; Song, Jen-Shin; Hsu, Tsu-An; Chao, Yu-Sheng; Yueh, Andrew; Chern, Jyh-Haur 分享 收藏 N-Indolylglycosides bearing modifications at the glucose C6-position as sodium-dependent glucose co-transporter 2 inhibitorsChu, Kuang-Feng; Yao, Chun-Hsu; Song, Jen-Shin; Chen, Chiung-Tong; Yeh, Teng-Kuang; Hsieh, Tsung-Chih; Huang, Chung-Yu; Wang, Min-Hsien; Wu, Szu-Huei; Chang, Wei-En; Chao, Yu-Sheng; Lee, Jinq-Chyi 分享 收藏 分享 收藏 Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5-(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a Novel Peripherally Restricted Cannabinoid-1 Receptor Antagonist with Significant Weight-Loss Efficacy in Diet-Induced Obese MiceChang, Chun-Ping; Wu, Chien-Huang; Song, Jen-Shin; Chou, Ming-Chen; Wong, Ying-Chieh; Lin, Yinchiu; Yeh, Teng-Kuang; Sadani, Amit A.; Ou, Ming-Hung; Chen, Kun-Hung; Chen, Pei-Hsuan; Kuo, Po-Chu; Tseng, Chen-Tso; Chang, Kuei-Hua; Tseng, Shi-Liang; Chao, Yu-Sheng; Hung, Ming-Shiu; Shia, Kak-Shan 分享 收藏 Optimization of Ligand and Lipophilic Efficiency To Identify an in Vivo Active Furano-Pyrimidine Aurora Kinase InhibitorShiao, Hui-Yi; Coumar, Mohane Selvaraj; Chang, Chun-Wei; Ke, Yi-Yu; Chi, Ya-Hui; Chu, Chang-Ying; Sun, Hsu-Yi; Chen, Chun-Hwa; Lin, Wen-Hsing; Fung, Ka-Shu; Kuo, Po-Chu; Huang, Chin-Ting; Chang, Kai-Yen; Lu, Cheng-Tai; Hsu, John T. A.; Chen, Chiung-Tong; Jiaang, Weir-Torn; Chao, Yu-Sheng; Hsieh, Hsing-Pang 分享 收藏 Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)Lin, Wen-Hsing; Hsu, John T. -A.; Hsieh, Shu-Yi; Chen, Chiung-Tong; Song, Jen-Shin; Yen, Shih-Chieh; Hsu, Tsu; Lu, Cheng-Tai; Chen, Chun-Hwa; Chou, Ling-Hui; Yang, Yung-Ning; Chiu, Ching-Hui; Chen, Ching-Ping; Tseng, Ya-Ju; Yen, Kuei-Jung; Yeh, Ching-Fang; Chao, Yu-Sheng; Yeh, Teng-Kuang; Jiaang, Weir-Torn 分享 收藏 分享 收藏 Resistance Studies of a Dithiazol Analogue, DBPR110, as a Potential Hepatitis C Virus NS5A Inhibitor in Replicon SystemsLin, Hui-Mei; Wang, Jing-Chyi; Hu, Han-Shu; Wu, Pei-Shan; Wang, Wen-Hung; Wu, Su-Ying; Yang, Chi-Chen; Yeh, Teng-Kuang; Hsu, Tsu-An; Jiaang, Weir-Torn; Chao, Yu-Sheng; Chern, Jyh-Haur; Yueh, Andrew 分享 收藏 3D-QSAR-Assisted Drug Design: Identification of a Potent Quinazoline-Based Aurora Kinase InhibitorKe, Yi-Yu; Shiao, Hui-Yi; Hsu, Yung Chang; Chu, Chang-Ying; Wang, Wen-Chieh; Lee, Yen-Chun; Lin, Wen-Hsing; Chen, Chun-Hwa; Hsu, John T. A.; Chang, Chun-Wei; Lin, Cheng-Wei; Yeh, Teng-Kuang; Chao, Yu-Sheng; Coumar, Mohane Selvaraj; Hsieh, Hsing-Pang 分享 收藏 Anti-influenza Drug Discovery: Identification of an Orally Bioavailable Quinoline Derivative through Activity- and Property-Guided Lead OptimizationYeh, Jiann-Yih; Coumar, Mohane Selvaraj; Shiao, Hui-Yi; Lin, Ta-Jen; Lee, Yen-Chun; Hung, Hui-Chen; Ko, Shengkai; Kuo, Fu-Ming; Fang, Ming-Yu; Huang, Yu-Lin; Hsu, John T. A.; Yeh, Teng-Kuang; Shih, Shin-Ru; Chao, Yu-Sheng; Horng, Jim-Tong; Hsieh, Hsing-Pang 分享 收藏 Resistance Analysis and Characterization of a Thiazole Analogue, BP008, as a Potent Hepatitis C Virus NS5A InhibitorLin, Hui-Mei; Wang, Jing-Chyi; Hu, Han-Shu; Wu, Pei-Shan; Yang, Chi-Chen; Wu, Chung-Pu; Pu, Szu-Yuan; Hsu, Tsu-An; Jiaang, Weir-Torn; Chao, Yu-Sheng; Chern, Jyh-Haur; Yeh, Teng-Kuang; Yueh, Andrew 分享 收藏 Discovery of Novel Stem Cell Mobilizers That Target the CXCR4 ReceptorWu, Chien-Huang; Chang, Chun-Ping; Song, Jen-Shin; Jan, Jiing-Jyh; Chou, Ming-Chen; Wu, Szu-Huei; Yeh, Kai-Chia; Wong, Ying-Chieh; Hsieh, Chieh-Jui; Chen, Chiung-Tong; Kao, Tzu-Ting; Wu, Su-Ying; Yeh, Ching-Fang; Tseng, Chen-Tso; Chao, Yu-Sheng; Shia, Kak-Shan 分享 收藏 分享 收藏 Discovery and evaluation of 3-phenyl-1H-5-pyrazolylamine-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)Lin, Wen-Hsing; Hsieh, Shu-Yi; Yen, Shih-Chieh; Chen, Chiung-Tong; Yeh, Teng-Kuang; Hsu, Tsu; Lu, Cheng-Tai; Chen, Ching-Ping; Chen, Chun-Wha; Chou, Ling-Hui; Huang, Yu-Lin; Cheng, An-Huei; Chang, Yun-I; Tseng, Ya-Ju; Yen, Kuei-Rong; Chao, Yu-Sheng; Hsu, John T. -A.; Jiaang, Weir-Torn 分享 收藏 
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