Steven Wrighton - Publications, H-index & Citations

Steven Wrighton

Eli Lilly

78H指数

440论文数

2.2W被引数

收录论文 7

发表时间

Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2012-04-01

OAAI

Noreault-Conti, Trisha L.; Fellows, Abigail; Jacobs, Judith M.; Trask, Heidi W.; Strom, Stephen C.; Evans, Ronald M.; Wrighton, Steven A.; Sinclair, Peter R.; Sinclair, Jacqueline F.; Nichols, Ralph C.

Metabolic capabilities of cytochrome P450 enzymes in Chinese liver microsomes compared with those in Caucasian liver microsomes 中国肝微粒体与高加索肝微粒体中细胞色素P450酶的代谢能力比较

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2012-01-06

OAAI

Yang, Junling; He, Minxia M.; Niu, Wei; Wrighton, Steven A.; Li, Li; Liu, Yang; Li, Chuan

Potentially increasing the metabolic stability of drug candidates via computational site of metabolism prediction by CYP2C9: The utility of incorporating protein flexibility via an ensemble of structures

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2011-09-01

OAAI

Danielson, Matthew L.; Desai, Prashant V.; Mohutsky, Michael A.; Wrighton, Steven A.; Lill, Markus A.

Genomic analysis of the carboxylesterases: Identification and classification of novel forms

MOLECULAR PHYLOGENETICS AND EVOLUTION

IF3.6

2010-10-01

PREAI

Williams, Eric T.; Wang, He; Wrighton, Steven A.; Qian, Yue-Wei; Perkins, Everett J.

Desipramine, substrate for CYP2D6 activity: population pharmacokinetic model and design elements of drug-drug interaction trials

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2010-09-14

OAAI

Gueorguieva, Ivelina; Jackson, Kimberley; Wrighton, Steven A.; Sinha, Vikram P.; Chien, Jenny Y.

Apparent high CYP3A5 expression is required for significant metabolism of vincristine by human cryopreserved hepatocytes

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2008-10-01

PREAI

Dennison, Jennifer B.; Mohutsky, Michael A.; Barbuch, Robert J.; Wrighton, Steven A.; Hall, Stephen D.

Effects of antipsychotic drugs on Ito, INa, Isus, IK1, and hERG:: QT prolongation, structure activity relationship, and network analysis

PHARMACEUTICAL RESEARCH

IF4.3

2006-05-25

PREAI

Crumb, William J., Jr.; Ekins, Sean; Sarazan, R. Dustan; Wikel, James H.; Wrighton, Steven A.; Carlson, Christopher; Beasley, Charles M., Jr.

研究方向