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Translational molecular imaging and drug development in sclerosis 多发性硬化症的分子影像学与药物开发 Tay, Daniel; Ahmed, Hazem; Dawoud, Alyaa; Salam, Mohamed; Gobbi, Luca; Grether, Uwe; Edelmann, Martin R.; Wittwer, Matthias B.; Collin, Ludovic; Atz, Kenneth; Keaney, James; Giroud, Maude; Rossi, Alexia; Gennari, Antonio Giulio; Pagano, Gennaro; Parrot, Neil John; Barakovic, Muhamed; Rominger, Axel; Gebhard, Catherine; Ametamey, Simon M.; Saindane, Amit M.; Liang, Steven H.; Haider, Achi 分享 收藏
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Discovery of 1,3,4-Oxadiazin-5-One Derivative CJ1-34 as a Partial ATP Synthase Inhibitor for CNS Applications Jie, Caitlin V. M. L.; Delparente, Aro; Reichert, Lisa; Albrecht, Manuela; Atz, Kenneth; Schneider, Gisbert; Schibli, Roger; Mu, Linjing 分享 收藏
Prospective de novo drug design with deep interactome learning Atz, Kenneth; Cotos, Leandro; Isert, Clemens; Hakansson, Maria; Focht, Dorota; Hilleke, Mattis; Nippa, David F.; Iff, Michael; Ledergerber, Jann; Schiebroek, Carl C. G.; Romeo, Valentina; Hiss, Jan A.; Merk, Daniel; Schneider, Petra; Kuhn, Bernd; Grether, Uwe; Schneider, Gisbert 分享 收藏
Geometric deep learning-guided Suzuki reaction conditions assessment for applications in medicinal chemistry Atz, Kenneth; Nippa, David F.; Mueller, Alex T.; Jost, Vera; Anelli, Andrea; Reutlinger, Michael; Kramer, Christian; Martin, Rainer E.; Grether, Uwe; Schneider, Gisbert; Wuitschik, Georg 分享 收藏
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning Nippa, David F.; Atz, Kenneth; Hohler, Remo; Muller, Alex T.; Marx, Andreas; Bartelmus, Christian; Wuitschik, Georg; Marzuoli, Irene; Jost, Vera; Wolfard, Jens; Binder, Martin; Stepan, Antonia F.; Konrad, David B.; Grether, Uwe; Martin, Rainer E.; Schneider, Gisbert 分享 收藏
Identifying opportunities for late-stage C-H alkylation with high-throughput experimentation and in silico reaction screening Nippa, David F.; Atz, Kenneth; Mueller, Alex T.; Wolfard, Jens; Isert, Clemens; Binder, Martin; Scheidegger, Oliver; Konrad, David B.; Grether, Uwe; Martin, Rainer E.; Schneider, Gisbert 分享 收藏
Allosteric targeting resolves limitations of earlier LFA-1 directed modalities Mancuso, Riccardo V.; Schneider, Gisbert; Hurzeler, Marianne; Gut, Martin; Zurfluh, Jonas; Breitenstein, Werner; Bouitbir, Jamal; Reisen, Felix; Atz, Kenneth; Ehrhardt, Claus; Duthaler, Urs; Gygax, Daniel; Schmidt, Albrecht G.; Krahenbuhl, Stephan; Weitz-Schmidt, Gabriele 分享 收藏
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Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Korn, Claudia; Sykes, David; Forn-Cuni, Gabriel; Pfaff, Patrick; Sarott, Roman C.; Westphal, Matthias, V; Mostinski, Yelena; Mach, Leonard; Wasinska-Kalwa, Malgorzata; Weise, Marie; Hoare, Bradley L.; Miljus, Tamara; Mexi, Maira; Roth, Nicolas; Koers, Eline J.; Guba, Wolfgang; Alker, Andre; Rufer, Arne C.; Kusznir, Eric A.; Huber, Sylwia; Raposo, Catarina; Zirwes, Elisabeth A.; Osterwald, Anja; Pavlovic, Anto; Moes, Svenja; Beck, Jennifer; Nettekoven, Matthias; Benito-Cuesta, Irene; Grande, Teresa; Drawnel, Faye; Widmer, Gabriella; Holzer, Daniela; van der Wel, Tom; Mandhair, Harpreet; Honer, Michael; Fingerle, Jurgen; Scheffel, Joerg; Broichhagen, Johannes; Gawrisch, Klaus; Romero, Julian; Hillard, Cecilia J.; Varga, Zoltan V.; van der Stelt, Mario; Pacher, Pal; Gertsch, Jurg; Ullmer, Christoph; McCormick, Peter J.; Oddi, Sergio; Spaink, Herman P.; Maccarrone, Mauro; Veprintsev, Dmitry B.; Carreira, Erick M.; Grether, Uwe; Nazare, Marc 分享 收藏
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Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells Sarott, Roman C.; Westphal, Matthias, V; Pfaff, Patrick; Korn, Claudia; Sykes, David A.; Gazzi, Thais; Brennecke, Benjamin; Atz, Kenneth; Weise, Marie; Mostinski, Yelena; Hompluem, Pattarin; Koers, Eline; Miljus, Tamara; Roth, Nicolas J.; Asmelash, Hermon; Vong, Man C.; Piovesan, Jacopo; Guba, Wolfgang; Rufer, Arne C.; Kusznir, Eric A.; Huber, Sylwia; Raposo, Catarina; Zirwes, Elisabeth A.; Osterwald, Anja; Pavlovic, Anto; Moes, Svenja; Beck, Jennifer; Benito-Cuesta, Irene; Grande, Teresa; de Martin Esteban, Samuel Ruiz; Yeliseev, Alexei; Drawnel, Faye; Widmer, Gabriella; Holzer, Daniela; van der Wel, Tom; Mandhair, Harpreet; Yuan, Cheng-Yin; Drobyski, William R.; Saroz, Yurii; Grimsey, Natasha; Honer, Michael; Fingerle, Juergen; Gawrisch, Klaus; Romero, Julian; Hillard, Cecilia J.; Varga, Zoltan V.; van der Stelt, Mario; Pacher, Pal; Gertsch, Juerg; McCormick, Peter J.; Ullmer, Christoph; Oddi, Sergio; Maccarrone, Mauro; Veprintsev, Dmitry B.; Nazare, Marc; Grether, Uwe; Carreira, Erick M. 分享 收藏
Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors Haider, Ahmed; Gobbi, Luca; Kretz, Julian; Ullmer, Christoph; Brink, Andreas; Honer, Michael; Woltering, Thomas J.; Muri, Dieter; Iding, Hans; Burkler, Markus; Binder, Martin; Bartelmus, Christian; Knuesel, Irene; Pacher, Pal; Herde, Adrienne Mueller; Spinelli, Francesco; Ahmed, Hazem; Atz, Kenneth; Keller, Claudia; Weber, Markus; Schibli, Roger; Mu, Linjing; Grether, Uwe; Ametamey, Simon M. 分享 收藏
Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors Haider, Ahmed; Kretz, Julian; Gobbi, Luca; Ahmed, Hazem; Atz, Kenneth; Burkler, Markus; Bartelmus, Christian; Fingerle, Jurgen; Guba, Wolfgang; Ullmer, Christoph; Honer, Michael; Knuesel, Irene; Weber, Markus; Brink, Andreas; Herde, Adrienne Mueller; Keller, Claudia; Schibli, Roger; Mu, Linjing; Grether, Uwe; Ametamey, Simon M. 分享 收藏
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