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Linli Li

sichuan university

28H指数
141论文数
3.0K被引数
收录论文 66
发表时间
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Identification of a Potent and Selective Small-Molecule Inhibitor Targeting the nNOS-PDZ Domain that Exhibits Rapid In Vivo Antidepressant Efficacy鉴定一种靶向nNOS-PDZ结构域的高效且选择性小分子抑制剂，该抑制剂显示出快速的体内抗抑郁功效
errJournal of Medicinal Chemistry
IF6.8
err2026-06-03
err0
PREAI
errLiting Zhang; Zijie Xiong; Shasha Chen; Qiucheng Zhu; Yifei Wang; Qi Lu; Xiaohan Bu; Anjie Xia; Lijuan Chen; Chong Chen; Zhenhua Shao; Linli Li; Shengyong Yang
err分享
err收藏
Small-molecule inhibition of YTHDC1 as a strategy against acute myeloid leukemia in mouse modelsYTHDC1的小分子抑制作为小鼠模型中急性髓系白血病的策略
errScience Translational Medicine
IF14.6
err2026-02-04
err0
PREAI
errHailin Zhang; Yueshan Li; Yin Zhao; Falu Wang; Guifeng Lin; Ting Niu; He Li; Yueyue Li; Lina Liu; Yue Liang; Yu Shen; Yuyao Yi; Hui Zhou; Shang Lou; Yishan Ye; Yanmin He; Ruicheng Yang; Rui Yao; Chenyu Tian; Pei Zhou; Mengdan Wu; Mingxin Chen; Haixing Xu; Jing You; Yi Liao; Chenlu Yang; Ailin Zhao; Chong Chen; Linli Li; Shanshan Pei; Shengyong Yang
err分享
err收藏
Discovery and Structure–Activity Relationship Studies of Diazepine Derivatives as a New Class of Ferroptosis Inhibitors with Potent Efficacy in the Doxorubicin-Induced Cardiomyopathy Model
errJournal of Medicinal Chemistry
IF6.8
err2026-01-30
err0
PREAI
errJing You; Lu Yang; Yaru Qin; Chenyu Tian; Xin Yang; Mingli Xiang; Linli Li; Shengyong Yang
err分享
err收藏
Aucubin inhibits the activity of lung cancer stem-like cells by targeting degradation of β-catenin京尼平通过靶向β-catenin的降解来抑制肺癌干细胞样细胞的活性。
errJOURNAL OF PHARMACY AND PHARMACOLOGY
IF3.2
err2025-09-01
err0
PREAI
errLi, Qian; Xie, Hao; Li, Linli; Yan, Wenying; Liu, Guoqiang
err分享
err收藏
Response of rice flower carp (Cyprinus carpio var.) to high-temperature stress: Mechanisms and limits of tolerance高温胁迫下鲤鱼（Cyprinus carpio var.）的响应：耐受机制与极限
errJournal of Thermal Biology
IF2.9
err2025-08-22
err0
PREAI
errChunxing Cheng; Wenfei Tian; Jinyou Wei; Linli Li; Haizhen Tan; Zhengjun Wu; Jiaoyun Jiang
err分享
err收藏
MSDUNet: A Model Based on Feature Multi-Scale and Dual-Input Dynamic Enhancement for Skin Lesion SegmentationMSDUNet：一种基于特征多尺度与双输入动态增强的皮肤病变分割模型
errIEEE Transactions on Medical Imaging
IF9.8
err2025-07-01
err0
PREAI
errXiaosen Li; Linli Li; Xinlong Xing; Huixian Liao; Wenji Wang; Qiutong Dong; Xiao Qin; Chang’an Yuan
err分享
err收藏
Discovery of 4-((quinolin-8-ylthio)methyl)benzamide derivatives as a new class of SARS-CoV-2 nsp13 inhibitors4-((喹啉-8-基硫)甲基)苯甲酰胺衍生物作为一类新的SARS-CoV-2 nsp13抑制剂的开发
errBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
IF2.2
err2025-07-01
err0
PREAI
errFan, Danchen; Huang, Yuanting; Yao, Rui; Zhang, Guo; Yang, Shengyong; Li, Linli
err分享
err收藏
Structural Optimization and Structure-Activity Relationship of 1H-Pyrazole-4-carboxylic Acid Derivatives as DNA 6mA Demethylase ALKBH1 Inhibitors and Their Antigastric Cancer Activity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-09-03
err0
PREAI
errLi, Feng; Xiong, Liang; Zhang, Jian; Guo, Yinping; Xu, Ke; Xiong, Zijie; Wang, Yuyang; Ji, Shanmian; Tong, Aiping; Li, Linli; Yang, Shengyong
err分享
err收藏
Identification of a new class of activators of the Hippo pathway with antitumor activity in vitro and in vivo
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2024-06-01
err0
PREAI
errLin, Guifeng; Xia, Anjie; Qiao, Jingxin; Zhang, Hailin; Chen, Pei; Zhou, Pei; Hu, Qian; Xiang, Zhiyu; Zhang, Shiyu; Li, Linli; Yang, Shengyong
err分享
err收藏
PocketFlow is a data-and-knowledge-driven structure-based molecular generative modelPocketFlow是一种数据和知识驱动的基于结构的分子生成模型
errNATURE MACHINE INTELLIGENCE
IF23.9
err2024-03-11
err5
errOAAI
errJiang, Yuanyuan; Zhang, Guo; You, Jing; Zhang, Hailin; Yao, Rui; Xie, Huanzhang; Zhang, Liyun; Xia, Ziyi; Dai, Mengzhe; Wu, Yunjie; Li, Linli; Yang, Shengyong
err分享
err收藏
Discovery of a Potent and Cell-Active Inhibitor of DNA 6mA Demethylase ALKBH1
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-03-04
err6
PREAI
errXiong, Liang; Li, Feng; Guo, Yinping; Zhang, Jian; Xu, Ke; Xiong, Zijie; Tong, Aiping; Li, Linli; Yang, Shengyong
err分享
err收藏
Discovery of a novel pyroptosis inhibitor acting though modulating glutathionylation to suppress NLRP3-related signal pathway发现一种通过调节谷胱甘肽化作用来抑制NLRP3-related信号通路的新型焦凋亡抑制剂
errINTERNATIONAL IMMUNOPHARMACOLOGY
IF4.7
err2024-01-01
err1
PREAI
errZhou, Nenghua; Zhang, Yun; Jiao, Yan; Nan, Jinshan; Xia, Anjie; Mu, Bo; Lin, Guifeng; Li, Xun; Zhang, Shanshan; Yang, Shengyong; Li, Linli
err分享
err收藏
From Hit to Lead: Structure-Based Optimization of Novel Selective Inhibitors of Receptor-Interacting Protein Kinase 1 (RIPK1) for the Treatment of Inflammatory Diseases
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-12-30
err2
PREAI
errZhang, Liting; Li, Yueshan; Tian, Chenyu; Yang, Ruicheng; Wang, Yifei; Xu, Haixing; Zhu, Qiucheng; Chen, Shasha; Li, Linli; Yang, Shengyong
err分享
err收藏
Discovery and structure-activity relationship studies of novel a-ketoamide derivatives targeting the SARS-CoV-2 main protease
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-11-01
err6
PREAI
errHuang, Chong; Zeng, Rui; Qiao, Jingxin; Quan, Baoxue; Luo, Ronghua; Huang, Qiao; Guo, Nihong; Li, Yueyue; Long, Xinyan; Ma, Ronggang; Xia, Anjie; Fang, Zhen; Wang, Yifei; Li, Yueshan; Zheng, Yongtang; Li, Linli; Lei, Jian; Yang, Shengyong
err分享
err收藏
Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5(vol 238, 114446, 2022)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-07-01
err1
PREAI
errFang, Zhen; Mu, Bo; Liu, Yang; Guo, Nihong; Xiong, Liang; Guo, Yinping; Xia, Anjie; Zhang, Rong; Zhang, Hailin; Yao, Rui; Fan, Yan; Li, Linli; Yang, Shengyong; Xiang, Rong
err分享
err收藏
Design, synthesis, and biological screening of a series of pyrazolo [1,5-a] quina-zoline derivatives as SIRT6 activators
errEUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
IF4.7
err2023-06-01
err3
errOAAI
errZhang, Ziling; Sun, Weining; Zhang, Guo; Fang, Zhen; Chen, Xiuli; Li, Linli
err分享
err收藏
Discovery of [1,2,3]Triazolo[4,5-c]quinoline Derivatives as a New Class of Ataxia-Telangiectasia Mutated Kinase Inhibitors[1,2，3] 三唑并 [4，5-c] 喹啉衍生物作为一类新的共济失调-毛细血管扩张症突变激酶抑制剂的发现
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2023-05-22
err5
errOAAI
errZhang, Shiyu; Zhou, Pei; Liu, Jingming; Xia, Anjie; Lin, Guifeng; Xiang, Zhiyu; Fang, Zhen; Yang, Xin; Qiao, Jingxin; Hu, Qian; Zhang, Jiahao; Zhao, Jinlong; Li, Linli
err分享
err收藏
Non-classical ferroptosis inhibition by a small molecule targeting PHB2靶向PHB2的小分子对非经典铁死亡的抑制作用
errNATURE COMMUNICATIONS
IF15.7
err2022-12-03
err26
errOAAI
errYang, Wei; Mu, Bo; You, Jing; Tian, Chenyu; Bin, Huachao; Xu, Zhiqiang; Zhang, Liting; Ma, Ronggang; Wu, Ming; Zhang, Guo; Huang, Chong; Li, Linli; Shao, Zhenhua; Dai, Lunzhi; Desaubry, Laurent; Yang, Shengyong
err分享
err收藏
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor生成式深度学习可以发现一种有效的选择性RIPK1抑制剂
errNATURE COMMUNICATIONS
IF15.7
err2022-11-12
err39
errOAAI
errLi, Yueshan; Zhang, Liting; Wang, Yifei; Zou, Jun; Yang, Ruicheng; Luo, Xinling; Wu, Chengyong; Yang, Wei; Tian, Chenyu; Xu, Haixing; Wang, Falu; Yang, Xin; Li, Linli; Yang, Shengyong
err分享
err收藏
Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R)
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2022-10-03
err8
PREAI
errYang, Xin; Lin, Guifeng; Xia, Anjie; Liu, Jingming; Zhang, Shiyu; Zhou, Pei; Wang, Yiwei; Zhang, Jiahao; Zhou, Yangli; Chen, Pei; Wang, Yifei; Zheng, Tao; Li, Linli; Yang, Shengyong
err分享
err收藏

研究方向

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合作学者
合作期刊
Y
Yuquan Wei
H 指数: 111 · 论文数: 1.2K
李
李亚平 (Yaping Li)
H 指数: 102 · 论文数: 1.1K
杨
杨薇 (Wei Yang)
H 指数: 100 · 论文数: 1.1K
刘
刘洋 (Yang Liu)
H 指数: 91 · 论文数: 762
Y
Yan Jiao
H 指数: 86 · 论文数: 271
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