Kaizhen Wang

h lee moffitt cancer center and research institute

H指数:17

被引数:690

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Allele-Specific GNAQ Q209 Mutations Reveal Context-Dependent Oncogenic Programs in Uveal Melanoma

等位基因特异的GNAQ Q209突变揭示葡萄膜黑色素瘤中依赖背景的致癌程序

Pigment Cell & Melanoma Research

IF2.6

2026-10-050

OAAI

A MAFG~MITF complex drives melanoma phenotype switching and progression

MAFG-MITF复合物驱动黑色素瘤表型转换和进展

Nature Communications

IF15.7

2026-05-210

OAAI

Near-Infrared Boron Difluoride-Based Photosensitizers Targeting Endoplasmic Reticulum Stress for Antitumor Immunotherapy

近红外二氟化硼基光敏剂靶向内质网应激用于抗肿瘤免疫治疗

Advanced Functional Materials

IF19

2026-01-150

PRE

Dual PARP/NAMPT Inhibitors for BRCA Wild-Type Triple-Negative Breast Cancer: Disrupting Homologous Recombination Repair and Activating Antitumor Immunity

PARP/NAMPT双抑制剂在BRCA野生型三阴性乳腺癌中的应用：干扰同源重组修复并激活抗肿瘤免疫

Journal of Medicinal Chemistry

IF6.8

2026-01-010

PRE

FRA1 drives melanoma metastasis through an actionable transcriptional network

FRA1通过一个可操作的转录网络驱动黑色素瘤转移

Oncogene

IF7.3

2025-11-240

OAAI

CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma

CDH3-AS1反义RNA增强P-cadherin翻译，并在黑色素瘤中充当肿瘤抑制因子。

Cell Reports

IF6.9

2025-10-010

OAAI

Constructing natural phenolic acid mesopores to enhance chemotherapy and reduce accompanied intestinal damage

构建天然酚酸介孔材料以增强化疗并减少伴随的肠道损伤

Journal of Controlled Release

IF11.5

2025-08-140

PRE

Discovery of a Novel Potent and Orally Efficacious PROTAC Degrader of HPK1 for Tumor Immunotherapy

发现一种新型强效且口服有效的HPK1 PROTAC降解剂，用于肿瘤免疫治疗

Journal of Medicinal Chemistry

IF6.8

2025-07-300

PRE

Discovery of dual PARP/NAMPT inhibitors for the treatment of BRCA wild-type triple-negative breast cancer

发现用于治疗BRCA野生型三阴性乳腺癌的双PARP/NAMPT抑制剂

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

IF2.2

2025-05-010

PRE

Discovery of 1,2,4-benzotriazine derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors

1,2,4-苯并三嗪衍生物作为新型造血祖细胞激酶1（HPK1）抑制剂的发现

BIOORGANIC CHEMISTRY

IF4.7

2025-03-011

PRE

Discovery, Synthesis, and Activity Evaluation of Novel Small-Molecule Inhibitors Targeting VISTA for Cancer Immunotherapy

新型小分子抑制剂的发现、合成及其靶向VISTA用于癌症免疫治疗的活性评价

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2025-02-271

PRE

Discovery of novel phenyl urea SHP2 inhibitors with anti-colon cancer and potential immunomodulatory effects

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2025-01-010

PRE

Discovery of small molecules for autophagy-lysosome degradation of immune checkpoint proteins

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-12-010

PRE

Discovery of Benzo[d]oxazoles as Novel Dual Small-Molecule Inhibitors Targeting PD-1/PD-L1 and VISTA Pathway

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-10-100

PRE

PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis

CANCER RESEARCH

IF16.6

2024-01-092

Discovery of Novel PD-L1 Inhibitors That Induce the Dimerization, Internalization, and Degradation of PD-L1 Based on the Fragment Coupling Strategy

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-12-189

PRE

Diagnosing Orthotopic Lung Tumor Using a NTR-Activatable Near-Infrared Fluorescent Probe by Tracheal Inhalation

ANALYTICAL CHEMISTRY

IF6.7

2023-09-128

PRE

Novel Benzimidazoles as Potent Small-Molecule Inhibitors and Degraders of V-Domain Ig Suppressor of T-Cell Activation (VISTA)

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2023-08-186

PRE

Design, synthesis, and evaluation of PD-1/PD-L1 small-molecule inhibitors bearing a rigid indane scaffold

带有刚性茚满支架的PD-1/PD-L1小分子抑制剂的设计，合成和评估

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-08-0111

PRE

Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)

MINI-REVIEWS IN MEDICINAL CHEMISTRY

IF3.3

2023-06-012

PRE

Kaizhen Wang

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