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M

Mark Gontsarik

Ghent University
H指数:16
被引数:825

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Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pKa of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo

硫代酰胺位于可质子化脂质的可质子化胺头基附近，可降低脂质纳米粒的pKa，并增强体外和体内的mRNA转染效率。

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2025-05-190
PRE
Yong Chen; Emily De Lombaerde; Aimée Bugler-Lamb; Zifu Zhong; Martijn J. Schuijs; Claudia M. Brenis Gomez; Jamie De Baere; Mark Gontsarik
Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity
NATURE COMMUNICATIONS
IF15.7
2024-12-060
OAAI
Hamouda, Ahmed E. I.; Filtjens, Jessica; Brabants, Elisabeth; Kancheva, Daliya; Debraekeleer, Ayla; Brughmans, Jan; Jacobs, Lotte; Bardet, Pauline M. R.; Knetemann, Elisabeth; Lefesvre, Pierre; Allonsius, Lize; Gontsarik, Mark; Varela, Ismael; Crabbe, Marian; Clappaert, Emile J.; Cappellesso, Federica; Caro, Aarushi A.; Peiro, Alicia Gordun; Fredericq, Luna; Hadadi, Eva; Senti, Mariona Estape; Schiffelers, Raymond; van Grunsven, Leo A.; Nana, Frank Aboubakar; De Geest, Bruno G.; Deschoemaeker, Sofie; De Koker, Stefaan; Lambolez, Florence; Laoui, Damya
A Fentanyl Hapten-Displaying Lipid Nanoparticle Vaccine that Non-Covalently Encapsulates a TLR7/8 Agonist and T-Helper Epitope Induces Protective Anti-Fentanyl Immunity
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
2024-11-211
PRE
Zhong, Zifu; Deventer, Marie H.; Chen, Yong; Vanhee, Stijn; Lammens, Ines; Deswarte, Kim; Huang, Yi; Ye, Tingting; Wang, Haixiu; Nuhn, Lutz; Vandeputte, Marthe M.; Gontsarik, Mark; Cui, Xiaole; Sanders, Niek N.; Lienenklaus, Stefan; Lambrecht, Bart N.; Baptista, Antonio P.; Stove, Christophe P.; G. De Geest, Bruno

研究方向

暂未获取到该数据
S
Stefan Salentinig
H 指数:32论文数:146被引数:3,252
Z
Zifu Zhong
H 指数:20论文数:60被引数:1,558
B
Bruno G. De Geest
H 指数:65论文数:313被引数:1.5万
Y
Yong Chen
H 指数:15论文数:60被引数:841
B
Bart N. Lambrecht
H 指数:123论文数:763被引数:6.3万
N
Niek N. Sanders
H 指数:58论文数:225被引数:1.2万
K
Kim Deswarte
H 指数:33论文数:85被引数:6,978
A
Anan Yaghmur
H 指数:50论文数:139被引数:6,925
E
Emily De Lombaerde
H 指数:8论文数:23被引数:271
T
Tingting Ye
H 指数:7论文数:20被引数:218