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赵东宇 封面图

赵东宇 (Dongyu Zhao)

Peking University医学生物信息学系主任、党支书
H指数:24
被引数:1,895

个人简介

任职于北京大学基础医学院医学生物信息学系主任、党支书。国家级高层次青年人才计划入选者，北京大学博雅青年学者，血管稳态与重构全国重点实验室PI。2013年于中国科学院北京基因组研究所获博士学位，先后在美国康奈尔大学休斯敦Methodist研究所、哈佛大学医学院从事博士后研究。2021年回国加入北京大学基础医学院，主要研究数智化表观遗传调控疾病基因挖掘和机制探索。

教育背景

  • 2013.12

    中国科学院北京基因组研究所 博士学位

工作经历

  • 2021.01 – 至今

    北京大学基础医学院

    医学生物信息学系主任、党支书

荣誉奖项

  1. 国家级高层次青年人才计划入选者
  2. 北京大学博雅青年学者
  3. 北京大学医学部教学优秀奖
  4. 基础医学院青年教师奖励基金
  5. 基础医学院优秀教学奖
Glycochenodeoxycholic acid promotes hepatocarcinogenesis by inducing hepatic progenitor cell differentiation into cancer-associated fibroblasts via sphingosine-1-phosphate receptor 2 signalling

Glycochenodeoxycholic acid通过诱导肝祖细胞分化为癌相关成纤维细胞，经由鞘氨醇-1-磷酸受体2信号通路促进肝细胞癌发生。

Biomarker Research
IF11.5
2025-12-170
OAAI
Lu Gao; Gang Lv; Ying Huang; Mengmeng Xue; Zhipeng Zhang; Jing Weng; Haoran Bai; Min Tao; Xi Luo; Yuhua Gao; Shiyao Feng; Xiaojuan Hou; Chen Zong; Xue Yang; Qiudong Zhao; Jinghua Jiang; Xinyu Zhu; Zhipeng Han; Changtao Jiang; Dongyu Zhao; Lixin Wei; Lulu Sun
Elucidating pathway-selective biased CCKBR agonism for Alzheimer’s disease treatment

阐明通路选择性偏向性CCKBR激动剂在阿尔茨海默病治疗中的应用

Cell
IF42.5
2025-11-200
PRE
Jia-Le Wang; Xue-Ying Sha; Yue Shao; Zi-Hao Zhang; Shen-Ming Huang; Hui Lin; Shi-Yi Gan; Nan Zhang; Xin-Yi Xia; Yu-Nan Sun; Jin-Hui Ding; Rui-Qi Zhao; Jie Cheng; Pan Shang; Jin-Peng Wang; Yan-Jun Liu; Fan Yang; Peng Xiao; Lu-Wen Wang; Dong-Yu Zhao
Erratum to “A highly potent small-molecule antagonist of exportin-1 selectively eliminates CD44+ CD24- enriched breast cancer stem-like cells” [Drug Resist. Updates 66 (2023) 100903]

勘误：“A highly potent small-molecule antagonist of exportin-1 selectively eliminates CD44+ CD24- enriched breast cancer stem-like cells” [Drug Resist. Updates 66 (2023) 100903]

Drug Resistance Updates
IF21.7
2025-09-040
PRE
Caigang Liu; Yixiao Zhang; Jiujiao Gao; Qi Zhang; Lisha Sun; Qingtian Ma; Xinbo Qiao; Xinnan Li; Jinchi Liu; Jiawen Bu; Zhan Zhang; Ling Han; Dongyu Zhao; Yongliang Yang
The macrophage-derived motor protein KIF13B enhances MERTK-mediated efferocytosis and prevents atherosclerosis in mice

巨噬细胞来源的运动蛋白KIF13B增强MERTK介导的胞葬作用并预防小鼠动脉粥样硬化

EUROPEAN HEART JOURNAL
IF35.6
2025-07-013
PRE
Xu, Yitong; Chen, Jingxuan; Liu, Yiran; Zhang, Ge; Miao, Guolin; Wu, Jingdong; Lu, Kaikai; Zhao, Yinqi; Zhang, Wenxi; Zheng, Liwen; Zhang, Lianxin; Chen, Jinxuan; Zhou, Zihao; Han, Yufei; Lai, Pingping; Guo, Jiabao; Wu, Donghui; Mei, Si; Zhang, Ling; Zhao, Yang; Huang, Wei; Wang, Yuhui; Tang, Junnan; Zhao, Dongyu; Xian, Xunde
Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co-Culture System

神经类器官通过在共培养系统中转移versican，保护工程化心肌组织免受糖脂毒性影响

Cell Proliferation
IF5.6
2025-06-030
OAAI
Baochen Bai; Jiting Li; Ze Wang; Yuhan Yang; Jieqing He; Gonglie Chen; Yufan Zhang; Yan Qi; Zhongjun Wan; Lin Cai; Run Wang; Kai Wang; Dongyu Zhao; Jingzhong Zhang; Weihua Huang; Ronald X. Xu; Mingzhai Sun; Xiao Han; Yan Liu; Donghui Zhang; Wanying Zhu; Jian Liu; Yuxuan Guo
Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease

动力蛋白KIF13B调控肝代谢以预防代谢功能障碍相关脂肪性肝病

MILITARY MEDICAL RESEARCH
IF22.9
2025-03-040
OA
Miao, Guo-Lin; Zhang, Wen-Xi; Xu, Yi-Tong; Liu, Yi-Ran; Lai, Ping-Ping; Guo, Jia-Bao; Chen, Gong-Lie; Chen, Jing-Xuan; Zhou, Zi-Hao; Li, Yan-Wei; Zhang, Chong; Ding, Yang; Zhang, Lian-Xin; Han, Yu-Fei; Chen, Jin-Xuan; Wu, Jing-Dong; Zhao, Yin-Qi; Mei, Si; Zhao, Yang; Ma, Yuan-Wu; Zhang, Ling; Huang, Wei; Zhao, Dong-Yu; Dong, Er-Dan; Wang, Yu-Hui; Xian, Xun-De

研究方向

建立精准的疾病基因识别方法和开发相关生物信息学分析工具疾病基因组变异研究疾病转录调控研究多组学数据研究开发基于第三代纳米孔测序数据的分析软件
K
Kaifu Chen
H 指数:39论文数:184被引数:7,267
Q
Qi Cao
H 指数:50论文数:201被引数:1.7万
L
Lili Zhang
H 指数:16论文数:60被引数:693
G
Guangyu Wang
H 指数:37论文数:272被引数:4,847
Y
Yanqiang Li
H 指数:33论文数:103被引数:3,258
Q
Qingshu Meng
H 指数:14论文数:29被引数:761
杨奕 封面图
杨奕
H 指数:26论文数:56被引数:2,465
J
Jie Lv
H 指数:23论文数:78被引数:2,531
B
Bo Xia
H 指数:13论文数:25被引数:806
S
Sen Zhu
H 指数:13论文数:40被引数:597