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mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype (vol 17, pg 1205, 2015) mTOR调节MAPKAPK2翻译以控制衰老相关的分泌表型 (vol 17，pg 1205，2015) Herranz, Nicolas; Gallage, Suchira; Mellone, Massimiliano; Wuestefeld, Torsten; Klotz, Sabrina; Hanley, Christopher J.; Raguz, Selina; Acosta, Juan Carlos; Innes, Andrew J.; Banito, Ana; Georgilis, Athena; Montoya, Alex; Wolter, Katharina; Dharmalingam, Gopuraja; Faull, Peter; Carroll, Thomas; Martinez-Barbera, Juan Pedro; Cutillas, Pedro; Reisinger, Florian; Heikenwalder, Mathias; Miller, Richard A.; Withers, Dominic; Zender, Lars; Thomas, Gareth J.; Gil, Jesus 分享 收藏
MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells Molina, Ester; Garcia-Gutierrez, Lucia; Junco, Vanessa; Perez-Olivares, Mercedes; de Yebenes, Virginia G.; Blanco, Rosa; Quevedo, Laura; Acosta, Juan C.; Marin, Ana V.; Ulgiati, Daniela; Merino, Ramon; Delgado, M. Dolores; Varela, Ignacio; Regueiro, Jose R.; Moreno de Alboran, Ignacio; Ramiro, Almudena R.; Leon, Javier 分享 收藏
Discovery of senolytics using machine learning 使用机器学习发现senolyics Smer-Barreto, Vanessa; Quintanilla, Andrea; Elliott, Richard J. R.; Dawson, John C.; Sun, Jiugeng; Campa, Victor M.; Lorente-Macias, Alvaro; Unciti-Broceta, Asier; Carragher, Neil O.; Acosta, Juan Carlos; Oyarzun, Diego A. 分享 收藏
Myc Inhibits p27-Induced Erythroid Differentiation of Leukemia Cells by Repressing Erythroid Master Genes without Reversing p27-Mediated Cell Cycle Arrest Acosta, Juan C.; Ferrandiz, Nuria; Bretones, Gabriel; Torrano, Veronica; Blanco, Rosa; Richard, Carlos; O'Connell, Brenda; Sedivy, John; Dolores Delgado, M.; Leon, Javier 分享 收藏
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage 衰老治疗可保留冷藏期间因细胞衰老而丧失的胆汁再生能力 Ferreira-Gonzalez, Sofia; Man, Tak Yung; Esser, Hannah; Aird, Rhona; Kilpatrick, Alastair M.; Rodrigo-Torres, Daniel; Younger, Nicholas; Campana, Lara; Gadd, Victoria L.; Dwyer, Benjamin; Aleksieva, Niya; Boulter, Luke; Macmillan, Mark T.; Wang, Yinmiao; Mylonas, Katie J.; Ferenbach, David A.; Kendall, Timothy J.; Lu, Wei-Yu; Acosta, Juan Carlos; Kurian, Dominic; O'Neill, Stephen; Oniscu, Gabriel C.; Banales, Jesus M.; Krimpenfort, Paul J.; Forbes, Stuart J. 分享 收藏
Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells Altea-Manzano, Patricia; Vandekeere, Anke; Edwards-Hicks, Joy; Roldan, Mar; Abraham, Emily; Lleshi, Xhordi; Guerrieri, Ania Naila; Berardi, Domenica; Wills, Jimi; Junior, Jair Marques; Pantazi, Asimina; Acosta, Juan Carlos; Sanchez-Martin, Rosario M.; Fendt, Sarah-Maria; Martin-Hernandez, Miguel; Finch, Andrew J. 分享 收藏
Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer Millar, Fraser R.; Pennycuick, Adam; Muir, Morwenna; Quintanilla, Andrea; Hari, Priya; Freyer, Elisabeth; Gautier, Philippe; Meynert, Alison; Grimes, Graeme; Coll, Carla Salomo; Zdral, Sofia; Victorelli, Stella; Teixeira, Vitor H.; Connelly, John; Passos, Joao F.; Ros, Marian A.; Wallace, William A. H.; Frame, Margaret C.; Sims, Andrew H.; Boulter, Luke; Janes, Sam M.; Wilkinson, Simon; Acosta, Juan Carlos 分享 收藏
MYC sensitises cells to apoptosis by driving energetic demand Edwards-Hicks, Joy; Su, Huizhong; Mangolini, Maurizio; Yoneten, Kubra K.; Wills, Jimi; Rodriguez-Blanco, Giovanny; Young, Christine; Cho, Kevin; Barker, Heather; Muir, Morwenna; Guerrieri, Ania Naila; Li, Xue-Feng; White, Rachel; Manasterski, Piotr; Mandrou, Elena; Wills, Karen; Chen, Jingyu; Abraham, Emily; Sateri, Kianoosh; Qian, Bin-Zhi; Bankhead, Peter; Arends, Mark; Gammoh, Noor; von Kriegsheim, Alex; Patti, Gary J.; Sims, Andrew H.; Acosta, Juan Carlos; Brunton, Valerie; Kranc, Kamil R.; Christophorou, Maria; Pearce, Erika L.; Ringshausen, Ingo; Finch, Andrew J. 分享 收藏
In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma Younger, Nicholas T.; Wilson, Mollie L.; Lyons, Anabel Martinez; Jarman, Edward J.; Meynert, Alison M.; Grimes, Graeme R.; Gournopanos, Konstantinos; Waddell, Scott H.; Tennant, Peter A.; Wilson, David H.; Guest, Rachel, V; Wigmore, Stephen J.; Acosta, Juan Carlos; Kendall, Timothy J.; Taylor, Martin S.; Sproul, Duncan; Mill, Pleasantine; Boulter, Luke 分享 收藏
Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence Fernandez-Duran, Irene; Quintanilla, Andrea; Tarrats, Nuria; Birch, Jodie; Hari, Priya; Millar, Fraser R.; Lagnado, Anthony B.; Smer-Barreto, Vanessa; Muir, Morwenna; Brunton, Valerie G.; Passos, Joao F.; Acosta, Juan Carlos 分享 收藏
Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27 Garcia-Gutierrez, Lucia; Bretones, Gabriel; Molina, Ester; Arechaga, Ignacio; Symonds, Catherine; Acosta, Juan C.; Blanco, Rosa; Fernandez, Adrian; Alonso, Leticia; Sicinski, Piotr; Barbacid, Mariano; Santamaria, David; Leon, Javier 分享 收藏
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype Hari, Priya; Millar, Fraser R.; Tarrats, Nuria; Birch, Jodie; Quintanilla, Andrea; Rink, Curtis J.; Fernandez-Duran, Irene; Muir, Morwenna; Finch, Andrew J.; Brunton, Valerie G.; Passos, Joao F.; Morton, Jennifer P.; Boulter, Luke; Acosta, Juan Carlos 分享 收藏
Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence Pantazi, Asimina; Quintanilla, Andrea; Hari, Priya; Tarrats, Nuria; Parasyraki, Eleftheria; Dix, Flora L.; Patel, Jaiyogesh; Chandra, Tamir; Acosta, Juan Carlos; Finch, Andrew J. 分享 收藏
Notch Signaling Mediates Secondary Senescence Teo, Yee Voan; Rattanavirotkul, Nattaphong; Olova, Nelly; Salzano, Angela; Quintanilla, Andrea; Tarrats, Nuria; Kiourtis, Christos; Muller, Miryam; Green, Anthony R.; Adams, Peter D.; Acosta, Juan-Carlos; Bird, Thomas G.; Kirschner, Kristina; Neretti, Nicola; Chandra, Tamir 分享 收藏
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration 旁分泌细胞衰老加剧胆道损伤并损害再生 Ferreira-Gonzalez, Sofia; Lu, Wei-Yu; Raven, Alexander; Dwyer, Benjamin; Man, Tak Yung; O'Duibhir, Eoghan; Lewis, Philip J. Starkey; Campana, Lara; Kendall, Tim J.; Bird, Thomas G.; Tarrats, Nuria; Acosta, Juan-Carlos; Boulter, Luke; Forbes, Stuart J. 分享 收藏
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition Young, Helen L.; Rowling, Emily J.; Bugatti, Mattia; Giurisato, Emanuele; Luheshi, Nadia; Arozarena, Imanol; Acosta, Juan-Carlos; Kamarashev, Jivko; Frederick, Dennie T.; Cooper, Zachary A.; Reuben, Alexandre; Gil, Jesus; Flaherty, Keith T.; Wargo, Jennifer A.; Vermi, William; Smith, Michael P.; Wellbrock, Claudia; Hurlstone, Adam 分享 收藏
Suppression of autophagy impedes glioblastoma development and induces senescence 抑制自噬阻碍胶质母细胞瘤的发展并诱导衰老 Gammoh, Noor; Fraser, Jane; Puente, Cindy; Syred, Heather M.; Kang, Helen; Ozawa, Tatsuya; Lam, Du; Acosta, Juan Carlos; Finch, Andrew J.; Holland, Eric; Jiang, Xuejun 分享 收藏
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype (vol 17, pg 1205, 2015) mTOR调节MAPKAPK2翻译以控制衰老相关的分泌表型 (vol 17，pg 1205，2015) Herranz, Nicolas; Gallage, Suchira; Mellone, Massimiliano; Wuestefeld, Torsten; Klotz, Sabrina; Hanley, Christopher J.; Raguz, Selina; Carlos Acosta, Juan; Innes, Andrew J.; Banito, Ana; Georgilis, Athena; Montoya, Alex; Wolter, Katharina; Dharmalingam, Gopuraja; Faull, Peter; Carroll, Thomas; Pedro Martinez-Barbera, Juan; Cutillas, Pedro; Reisinger, Florian; Heikenwalder, Mathias; Miller, Richard A.; Withers, Dominic; Zender, Lars; Thomas, Gareth J.; Gil, Jesus 分享 收藏
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