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Alex Montoya

MRC Laboratory of Medical Sciences
H指数:22
被引数:1,984

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WEE1 opposes APC/CCDH1 activity to promote S phase entry

WEE1拮抗APC/CCDH1活性以促进S期进入

Nature
IF48.5
2026-10-210
OAAI
Luc-Alban Vuillemenot; Lucas G. Morales; Calin-Mihai Dragoi; Betheney R. Pennycook; Edward Harris; Liuyang C. Lin; William A. Weston; Jade-Ellen Brown; Emma Graham; Leelou Moulin; Ivan Andrew; Georgia Roumelioti; Alex Montoya; Laurence Game; George R. Young; Keshava K. Datta; Pavel Shliaha; Béla Novák; Hiroyuki Yamano; Alexis R. Barr
Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability

亲电化合物筛选鉴定出GPX4依赖性铁死亡为衰老的易损性

Nature Cell Biology
IF19.1
2026-04-240
OAAI
Mariantonietta D’Ambrosio; Matthew E. H. White; Efthymios S. Gavriil; Laura Bousset; Jodie Birch; Aleksandra Gruevska; Emiliano Pasquini; Manuel Colucci; Winnie Fong; Simone Mosole; Aurora Valdata; Dimitris Veroutis; Katie Tyson; Vikas Ranvir; Sandra Prokosch; Joaquim Pombo; Aoki Ardisson; Sanjay Khadayate; George Young; Alex Montoya; Georgia Roumelioti; Jack Houghton; Jianan Lu; Pavel V. Shliaha; Elena De Vita; Santiago Vernia; Vassilis G. Gorgoulis; Suchira Gallage; Mathias Heikenwälder; Zoe Hall; Andrea Alimonti; Iain A. McNeish; Edward W. Tate; Jesús Gil
Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors

多模态成像揭示了一种溶酶体药物贮库，该贮库驱动PARP抑制剂分布的异质性

Nature Communications
IF15.7
2026-03-170
OAAI
Carmen R. Moncayo; Restuadi Restuadi; Guanying Zhang; Daniel Marks; Paula Ortega-Prieto; Emily Doherty; Nathalie Lambie; Chad Whilding; Ivan Andrew; Alex Montoya; Bhavik Patel; Katie Tyson; Betheney R. Pennycook; Lauren Pendergast; Vincen Wu; Zoltan Takats; Nik Matthews; George R. Young; Priyanka Verma; Pavel Shliaha; Laurence Game; Boris Lenhard; Iain McNeish; Christina Fotopoulou; Alexis R. Barr; Paula Cunnea; Zoe Hall; Louise Fets
In vivo functional profiling and structural characterization of the human GLP1R A316T variant
Science Advances
IF12.5
2026-02-040
OA
Liliane El Eid; Yusman Manchanda; Gregory Austin; Kieran Deane-Alder; Roxana-Maria Rujan; Zamara Mariam; Affiong I. Oqua; Matthew J. Belousoff; Jorge Bernardino de la Serna; Kyle W. Sloop; Guy A. Rutter; Alex Montoya; Dominic J. Withers; Steven J. Millership; Karim Bouzakri; Ben Jones; Christopher A. Reynolds; Patrick M. Sexton; Denise Wootten; Giuseppe Deganutti; Alejandra Tomas
GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate β-cell mitochondrial remodelling and function

GLP-1R在ERMCSs处与VAPB和SPHKAP相互作用，以调节β细胞线粒体重塑和功能。

Nature Communications
IF15.7
2025-12-100
OA
Gregory Austin; Affiong I. Oqua; Liliane El Eid; Mingli Zhu; Yusman Manchanda; Priyanka Peres; Helena Coyle; Yelyzaveta Poliakova; Zhanna Balkhiyarova; Karim Bouzakri; Alex Montoya; Dominic J. Withers; Michele Solimena; Ben Jones; Steven J. Millership; Steffen Burgold; David C. A. Gaboriau; Endre Majorovits; Evelyn Garlick; Maria Augusta do R. B. F. Lima; Inga Prokopenko; Jonathon Nixon-Abell; Andreas Müller; Alejandra Tomas
PBK/TOPK mediates Ikaros, Aiolos and CTCF displacement from mitotic chromosomes and alters chromatin accessibility at selected C2H2-zinc finger protein binding sites

PBK/TOPK介导Ikaros、Aiolos和CTCF从有丝分裂染色体上位移，并改变选定C2H2锌指蛋白结合位点的染色质可及性。

Nature Communications
IF15.7
2025-09-230
OA
Andrew Dimond; Do Hyeon Gim; Elizabeth Ing-Simmons; Chad Whilding; Holger B. Kramer; Dounia Djeghloul; Alex Montoya; Bhavik Patel; Sherry Cheriyamkunnel; Karen E. Brown; Pavel V. Shliaha; Juan M. Vaquerizas; Matthias Merkenschlager; Amanda G. Fisher
Chemotherapy modulation by a cancer-associated microbiota metabolite

肿瘤相关微生物组代谢物对化疗的调节

Cell Systems
IF7.7
2025-09-100
OAAI
Daniel Martinez-Martinez; Tanara V. Peres; Kristin Gehling; Leonor Quintaneiro; Cecilia Cabrera; Maksym Cherevatenko; Stephen J. Cutty; Lena Best; Georgios Marinos; Johannes Zimmerman; Ayesha Safoor; Despoina Chrysostomou; Joao B. Mokochinski; Alex Montoya; Susanne Brodesser; Michalina Zatorska; Timothy Scott; Ivan Andrew; Holger Kramer; Masuma Begum; Bian Zhang; Bernard T. Golding; Julian R. Marchesi; Susumu Hirabayashi; Christoph Kaleta; Alexis R. Barr; Christian Frezza; Helena M. Cochemé; Filipe Cabreiro
Enhancing autophagy by redox regulation extends lifespan in Drosophila

通过氧化还原调控增强自噬可延长果蝇寿命

Nature Communications
IF15.7
2025-06-250
OAAI
Claudia Lennicke; Ivana Bjedov; Sebastian Grönke; Katja E. Menger; Andrew M. James; Jorge Iván Castillo-Quan; Lucie A. G. van Leeuwen; Andrea Foley; Marcela Buricova; Jennifer Adcott; Alex Montoya; Holger B. Kramer; Pavel V. Shliaha; Angela Logan; Filipe Cabreiro; Michael P. Murphy; Linda Partridge; Helena M. Cochemé
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype (vol 17, pg 1205, 2015)

mTOR调节MAPKAPK2翻译以控制衰老相关的分泌表型 (vol 17，pg 1205，2015)

NATURE CELL BIOLOGY
IF19.1
2024-05-221
OA
Herranz, Nicolas; Gallage, Suchira; Mellone, Massimiliano; Wuestefeld, Torsten; Klotz, Sabrina; Hanley, Christopher J.; Raguz, Selina; Acosta, Juan Carlos; Innes, Andrew J.; Banito, Ana; Georgilis, Athena; Montoya, Alex; Wolter, Katharina; Dharmalingam, Gopuraja; Faull, Peter; Carroll, Thomas; Martinez-Barbera, Juan Pedro; Cutillas, Pedro; Reisinger, Florian; Heikenwalder, Mathias; Miller, Richard A.; Withers, Dominic; Zender, Lars; Thomas, Gareth J.; Gil, Jesus
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity

Nnat的差异CpG甲基化在 β 细胞异质性早期建立中的作用

DIABETOLOGIA
IF10.2
2024-03-211
OAAI
Yu, Vanessa; Yong, Fiona; Marta, Angellica; Khadayate, Sanjay; Osakwe, Adrien; Bhattacharya, Supriyo; Varghese, Sneha S.; Chabosseau, Pauline; Tabibi, Sayed M.; Chen, Keran; Georgiadou, Eleni; Parveen, Nazia; Suleiman, Mara; Stamoulis, Zoe; Marselli, Lorella; De Luca, Carmela; Tesi, Marta; Ostinelli, Giada; Delgadillo-Silva, Luis; Wu, Xiwei; Hatanaka, Yuki; Montoya, Alex; Elliott, James; Patel, Bhavik; Demchenko, Nikita; Whilding, Chad; Hajkova, Petra; Shliaha, Pavel; Kramer, Holger; Ali, Yusuf; Marchetti, Piero; Sladek, Robert; Dhawan, Sangeeta; Withers, Dominic J.; Rutter, Guy A.; Millership, Steven J.
AMPK activation protects against prostate cancer by inducing a catabolic cellular state

AMPK激活通过诱导分解代谢细胞状态来预防前列腺癌

CELL REPORTS
IF6.9
2023-04-0119
OAAI
Penfold, Lucy; Woods, Angela; Pollard, Alice E.; Arizanova, Julia; Pascual-Navarro, Eneko; Muckett, Phillip J.; Dore, Marian H.; Montoya, Alex; Whilding, Chad; Fets, Louise; Mokochinski, Joao; Constantin, Theodora A.; Varela-Carver, Anabel; Leach, Damien A.; Bevan, Charlotte L.; Niktin, Alexander Yu.; Hall, Zoe; Carling, David
Report ATM/ATR kinases link the synaptonemal complex and DNA double-strand break repair pathway choice
CURRENT BIOLOGY
IF7.5
2022-11-018
OAAI
Lascarez-Lagunas, Laura I.; Nadarajan, Saravanapriah; Martinez-Garcia, Marina; Quinn, Julianna N.; Todisco, Elena; Thakkar, Tanuj; Berson, Elizaveta; Eaford, Don; Crawley, Oliver; Montoya, Alex; Faull, Peter; Ferrandiz, Nuria; Barroso, Consuelo; Labella, Sara; Koury, Emily; Smolikove, Sarit; Zetka, Monique; Martinez-Perez, Enrique; Colaiacovo, Monica P.
Indisulam targets RNA splicing and metabolism to serve as a therapeutic strategy for high-risk neuroblastoma
NATURE COMMUNICATIONS
IF15.7
2022-03-1636
OAAI
Nijhuis, Anke; Sikka, Arti; Yogev, Orli; Herendi, Lili; Balcells, Cristina; Ma, Yurui; Poon, Evon; Eckold, Clare; Valbuena, Gabriel N.; Xu, Yuewei; Liu, Yusong; da Costa, Barbara Martins; Gruet, Michael; Wickremesinghe, Chiharu; Benito, Adrian; Kramer, Holger; Montoya, Alex; Carling, David; Want, Elizabeth J.; Jamin, Yann; Chesler, Louis; Keun, Hector C.
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis

2型糖尿病相关的C2cd4b基因在小鼠葡萄糖稳态中的性双态作用

DIABETOLOGIA
IF10.2
2021-01-258
OAAI
Mousavy Gharavy, S. Neda; Owen, Bryn M.; Millership, Steven J.; Chabosseau, Pauline; Pizza, Grazia; Martinez-Sanchez, Aida; Tasoez, Emirhan; Georgiadou, Eleni; Hu, Ming; Fine, Nicholas H. F.; Jacobson, David A.; Dickerson, Matthew T.; Idevall-Hagren, Olof; Montoya, Alex; Kramer, Holger; Mehta, Zenobia; Withers, Dominic J.; Ninov, Nikolay; Gadue, Paul J.; Cardenas-Diaz, Fabian L.; Cruciani-Guglielmacci, Celine; Magnan, Christophe; Ibberson, Mark; Leclerc, Isabelle; Voz, Marianne; Rutter, Guy A.

研究方向

暂未获取到该数据
H
Holger Kramer
H 指数:39论文数:143被引数:5,737
P
Peter Faull
H 指数:26论文数:62被引数:2,617
D
Dominic J. Withers
H 指数:60论文数:157被引数:1.9万
P
Pedro R. Cutillas
H 指数:48论文数:574被引数:1.4万
P
Pavel V. Shliaha
H 指数:23论文数:67被引数:2,495
C
Chad Whilding
H 指数:11论文数:43被引数:648
G
Guy A. Rutter
H 指数:94论文数:666被引数:3.0万
J
Jesús Gil
H 指数:72论文数:232被引数:2.9万
S
Suchira Gallage
H 指数:18论文数:49被引数:2,846
L
Luís Aragón
H 指数:32论文数:83被引数:4,353