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J

Jianjun Chen

southern medical university

45H指数
189论文数
6.3K被引数
收录论文 110
发表时间
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RPE65 variant spectrum and structural analysis in Chinese patients with Leber congenital amaurosis中国Leber先天性黑矇患者的RPE65变异谱及结构分析
errEuropean Journal of Medical Research
IF3.4
err2026-08-18
err0
errOAAI
errHaining Li; Yu Chen; Yuanyuan Yang; Yunlong Meng; Kangyu Liu; Xingkun Tang; Zilin Zhong; Jianjun Chen
err分享
err收藏
Discovery of a small molecule RIOK1 inhibitor CINS-1 against colorectal cancer via disrupting ribosomal biosynthesis通过干扰核糖体生物合成发现一种小分子RIOK1抑制剂CINS-1用于结直肠癌治疗
errActa Pharmaceutica Sinica B
IF14.6
err2026-07-08
err0
errOAAI
errYing Jiang; Chuan Huang; Fang Wu; Guolong Liu; Shanhe Wan; Yongxin Chen; Ruohong Yan; Zichao Yang; Yuanxin Tian; Tingting Zhang; Xiaoyun Wu; Le Yu; Shaoyu Wu; Shuwen Liu; Jianjun Chen; Wei Xu; Jiajie Zhang
err分享
err收藏
Exogenous Epstein–Barr virus nuclear antigen 1 induces ADAR1-driven tumor resistance against immunotherapy外源性爱泼斯坦-巴尔病毒核抗原1诱导ADAR1-driven肿瘤对免疫治疗的耐药性
errSignal Transduction and Targeted Therapy
IF52.7
err2026-02-18
err0
errOAAI
errChanglin Liu; Zhiqiang Sun; Chao Li; Yanqing Zhou; Xuefeng Gao; Yuping Zhong; Xiaomin Luo; Chenci Wang; Yuanbin Zhang; Chuping Ni; Manli Peng; Weiquan Jian; Yinggui Yang; Xuewen Zhang; Yichang Ren; Xinqi Gong; Min Zhao; Xia Guo; Chao Cheng; Jianjun Chen; Xin Li
err分享
err收藏
Discovery of the first dual PD-L1/JAK inhibitor with enhanced in vivo antitumor immunity
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-01-22
err0
PREAI
errZhijie Wang; HaiQi He; Jianwei Xu; Xiaotong Liao; Jun Tan; Chenglong Xu; Jiamin Tan; Lirong Zhang; Qin Wang; Xixiang Yang; Yichang Ren; Guangfa Wang; Yanle Zhi; Jianjun Chen
err分享
err收藏
Discovery of novel quinazoline analogs as tubulin inhibitors targeting the colchicine binding site for potent antitumor therapy in combination with PD-L1 inhibitors新型喹唑啉类似物的发现：作为靶向秋水仙素结合位点的微管蛋白抑制剂，用于与PD-L1抑制剂联合的强效抗肿瘤疗法
errBioorganic Chemistry
IF4.7
err2025-11-30
err0
PREAI
errYichang Ren; Songwen Zhou; Chenglong Xu; Jiamin Tan; Xixiang Yang; Zichao Yang; Xiaopeng Peng; Jin Liu; Jianjun Chen
err分享
err收藏
Spop-binding bifunctional degraders: a novel approach for cancer immunotherapySpop结合双功能降解剂：癌症免疫治疗的一种新方法
errJournal of Advanced Research
IF13
err2025-11-25
err0
errOAAI
errBinbin Cheng; Zhihua Kong; Yaru Shi; Yinrong Wu; Jing-Jing Du; Shuanghu Wang; Jianjun Chen; Congcong Wen
err分享
err收藏
Novel Imidazo[1,2-a]pyridine-Based Tubulin Polymerization Inhibitors: Structure-Activity Relationships and Anti-tumor Immune Potentiation新型基于咪唑并[1,2-a]吡啶的微管聚合抑制剂：构效关系及抗肿瘤免疫增强
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-11-08
err0
PREAI
errBinbin Cheng; Chao Li; Xixiang Yang; Yinrong Wu; Yong Ruan; Yichang Ren; Zhenhong Su; Shanhe Wan; Xin Li; Dulin Kong; Jianjun Chen
err分享
err收藏
Targeted NAT10 Degradation by PROTAC NP1192 Suppresses Hypoxia-Adaptive Glycolysis and Reinvigorates CD8+ Effector T-Cell Function for Synergistic Cancer ImmunotherapyNP1192通过靶向NAT10降解抑制缺氧适应性糖酵解，并重新激活CD8+效应T细胞功能，以实现协同癌症免疫疗法。
errACS Central Science
IF10.4
err2025-09-16
err0
errOAAI
errKeyi Ao; Zhiqiang Sun; Yi Hao; Jiaqi Qin; Chenglong Xu; Xiuli Wen; Zichao Yang; Li Li; Shaoyan Gan; Xiaona Chen; Xin Li; Jian Zhang; Jianjun Chen; Xia Guo
err分享
err收藏
Akkermansia muciniphila-derived SCFAs improve the depression-like behaviors of mice by inhibiting neuroinflammationAkkermansia muciniphila衍生的SCFAs通过抑制神经炎症改善小鼠的抑郁样行为
errPharmacological Research
IF10.5
err2025-08-29
err0
errOAAI
errJiaolin Wang; Jing Xie; Fei He; Wentao Wu; Ke Xu; Yi Ren; Jianjun Chen; Peng Xie
err分享
err收藏
Correction to “Small-Molecule Modulators Targeting Coactivator-Associated Arginine Methyltransferase 1 (CARM1) as Therapeutic Agents for Cancer Treatment: Current Medicinal Chemistry Insights and Emerging Opportunities”对“靶向共激活因子相关精氨酸甲基转移酶1（CARM1）的小分子调节剂作为癌症治疗的治疗剂：当前药物化学见解和新兴机遇”的更正
errJournal of Medicinal Chemistry
IF6.8
err2025-07-15
err0
PREAI
errShuqing Li; Wanyi Pan; Chengpeng Tao; Zhihao Hu; Binbin Cheng; Jianjun Chen; Xiaopeng Peng
err分享
err收藏
Research Progress in Targeting GSPT1: Molecular Glues; Bifunctional Degraders; and Antibody-Enabled Molecular Glues for Cancer Therapy靶向GSPT1的研究进展：分子胶；双功能降解剂；及用于癌症治疗的抗体辅助分子胶
errJournal of Medicinal Chemistry
IF6.8
err2025-06-26
err0
PREAI
errBinbin Cheng; Yaping Wang; Yimeng Hong; Yingxing Zhou; Jianjun Chen; Chunlai Zeng
err分享
err收藏
Caffeine plays a prevention role in stress-induced depression by modulating gut-brain axis function咖啡因通过调节肠道-大脑轴功能，在压力诱导的抑郁症中发挥预防作用。
errEUROPEAN JOURNAL OF PHARMACOLOGY
IF4.7
err2025-06-04
err0
PREAI
errWu, Wentao; Wang, Jiaolin; Chen, Jianjun; Xie, Jing; Xu, Ke; Ren, Yi; Zhong, Qi; He, Fei; Wang, Ying; Xie, Peng
err分享
err收藏
Targeted protein degradation with small molecules for cancer immunotherapy靶向蛋白降解的抗癌免疫疗法
errAsian Journal of Pharmaceutical Sciences
IF11.9
err2025-04-22
err0
errOAAI
errZichao Yang; Jianwei Xu; Xixiang Yang; Jianjun Chen
err分享
err收藏
Research progress in DNA damage response (DDR)-targeting modulators: From hits to clinical candidates
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-04-01
err0
PREAI
errCheng, Binbin; Ding, Zongbao; Hong, Yimeng; Wang, Yaping; Zhou, Yingxing; Chen, Jianjun; Peng, Xiaopeng; Zeng, Chunlai
err分享
err收藏
N-Iodosuccinimide-Promoted Synthesis of Indolo[3,2-c]quinolizines via Cascade Intramolecular C-N Bond Formation/Aromatization with 3-(1H-Indol-3-yl)-2-(pyridin-2-yl)propanoates
errJOURNAL OF ORGANIC CHEMISTRY
IF3.6
err2025-04-01
err0
PREAI
errChen, Chen; Yang, Xixiang; Wang, Jiaxin; Kong, Weiya; Chen, Jianjun; Tang, Xiaodong
err分享
err收藏
Research progress in bifunctional small molecules for cancer immunotherapy
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-03-01
err0
PREAI
errCheng, Binbin; Li, Hongqiao; Hong, Yimeng; Zhou, Yingxing; Chen, Jianjun; Shao, Chuxiao; Kong, Zhihua
err分享
err收藏
Recent progress in the development of peptide-drug conjugates (PDCs) for cancer therapy
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
PREAI
errHe, Haiqi; Deng, Xin; Wang, Zhijie; Chen, Jianjun
err分享
err收藏
Recent advances in developing targeted protein degraders靶向蛋白降解剂的研究进展
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err0
PREAI
errCheng, Binbin; Li, Hongqiao; Peng, Xiaopeng; Chen, Jianjun; Shao, Chuxiao; Kong, Zhihua
err分享
err收藏
Small molecule inhibitors targeting PD-L1, CTLA4, VISTA, TIM-3, and LAG3 for cancer immunotherapy (2020-2024)
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-02-01
err1
PREAI
errCheng, Binbin; Lv, Jinke; Xiao, Yao; Song, Changshan; Chen, Jianjun; Shao, Chuxiao
err分享
err收藏
Recent Progress and Future Perspectives on Anti-Hyperuricemic Agents
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-08
err0
PREAI
errSun, Zhiqiang; Zhang, Xuewen; Zhao, Zean; Li, Xiaoxun; Pang, Jianxin; Chen, Jianjun
err分享
err收藏

研究方向

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合作学者
合作期刊
张
张先正 (Xian‐Zheng Zhang)
H 指数: 124 · 论文数: 854
A
Andrzej Słomiński
H 指数: 113 · 论文数: 631
李威 封面图
李威 (Wěi Li)
H 指数: 107 · 论文数: 2.2K
C
Chen‐Yu Zhang
H 指数: 105 · 论文数: 778
张建 封面图
张建 (Jian Zhang)
H 指数: 99 · 论文数: 1.6K
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