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收藏分享 收藏 分享 收藏 Discovery of First-in-Class Carbonic Anhydrase/Histone Deacetylase Dual Inhibitors with Antiproliferative Activity in Cancer Cells
Bozdag, Murat; Mroweh, Nabil; Raucci, Alessia; Angeli, Andrea; Peppicelli, Silvia; Biagioni, Alessio; Calorini, Lido; Trisciuoglio, Daniela; Ragno, Rino; Astolfi, Roberta; Giuliani, Lidia; Zwergel, Clemens; Valente, Sergio; Andreucci, Elena; Carta, Fabrizio; Mai, Antonello; Supuran, Claudiu T. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 A Xanthine Derivative With Novel Heat Shock Protein 90-Alpha Inhibitory and Senolytic PropertiesAtlante, Sandra; Cis, Luca; Pirolli, Davide; Zamperla, Michela Gottardi; Barbi, Veronica; Mai, Antonello; Zwergel, Clemens; Marcozzi, Serena; Giuliani, Maria Elisa; Bigossi, Giorgia; Lai, Giovanni; Orlando, Fiorenza; Giacconi, Robertina; Lattanzio, Fabrizia; Matacchione, Giulia; Giordani, Chiara; Bracci, Massimo; Olivieri, Fabiola; Boschi, Federico; De Fatis, Paola Tabarelli; Ivaldi, Giovanni Battista; Malavolta, Marco; Farsetti, Antonella; De Rosa, Maria Cristina; Gaetano, Carlo 分享 收藏 Procognitive Potential of Neuroprotective Triazine 5-HT6 Receptor Antagonists Tested on Chronic Activity In Vivo in Rats: Computer-Aided Insight into the Role of Chalcogen-Differences on the Pharmacological Profile神经保护性三嗪类5-HT6受体拮抗剂的促认知潜力：通过计算机辅助研究在体大鼠慢性实验中硫族差异对药理学谱的作用Jastrzebska-Wiesek, M; Garbo, S; Cios, A; Wilczynska-Zawal, N; Partyka, A; Honkisz-Orzechowska, E; Zeslawska, E; Handzlik, J; Mordyl, B; Gluch-Lutwin, M; Raucci, A; Hittinger, M; Starek, M; Dabrowska, M; Nitek, W; Karcz, T; Skórkowska, A; Joanna, A; Czarnota-Lydka, K; Pyka, P; Szymanska, E; Kucwaj-Brysz, K; Zwergel, C; Wesolowska, A; Battistelli, C; Handzlik, J 分享 收藏 分享 收藏 HDAC3 genetic and pharmacologic inhibition radiosensitizes fusion positive rhabdomyosarcoma by promoting DNA double-strand breaksCassandri, Matteo; Porrazzo, Antonella; Pomella, Silvia; Noce, Beatrice; Zwergel, Clemens; Aiello, Francesca Antonella; Vulcano, Francesca; Milazzo, Luisa; Camero, Simona; Pajalunga, Deborah; Spada, Massimo; Manzi, Valeria; Gravina, Giovanni Luca; Codenotti, Silvia; Piccione, Michela; Tomaciello, Miriam; Signore, Michele; Barillari, Giovanni; Marchese, Cinzia; Fanzani, Alessandro; De Angelis, Biagio; Quintarelli, Concetta; Vakoc, Christopher R.; Chen, Eleanor Y.; Megiorni, Francesca; Locatelli, Franco; Valente, Sergio; Mai, Antonello; Rota, Rossella; Marampon, Francesco 分享 收藏 分享 收藏 HDAC3 sustains resistance to hypofractionated radiotherapy in fusion positve rhabdomyosarcoma cellsCassandri, Matteo; Porrazzo, Antonella; Pomella, Silvia; Camero, Simona; Aiello, Francesca A.; D'Archivio, Lucrezia; Zwergel, Clemens; Noce, Beatrice; Tomaciello, Miriam; Vulcano, Francesca; Milazzo, Luisa; Pedini, Francesca; Signore, Michele; Fanzani, Alessandro; Marchese, Cinzia; Minniti, Giuseppe; Valente, Sergio; Mai, Antonello; Megiorni, Francesca; Rota, Rossella; Marampon, Francesco 分享 收藏 分享 收藏 HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-α5β1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodelingTerri, Michela; Sandoval, Pilar; Bontempi, Giulio; Montaldo, Claudia; Tomero-Sanz, Henar; de Turris, Valeria; Trionfetti, Flavia; Pascual-Anton, Lucia; Clares-Pedrero, Irene; Battistelli, Cecilia; Valente, Sergio; Zwergel, Clemens; Mai, Antonello; Rosano, Laura; del Pozo, Miguel angel; Sanchez-Alvarez, Miguel; Cabanas, Carlos; Tripodi, Marco; Lopez-Cabrera, Manuel; Strippoli, Raffaele 分享 收藏 First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT6 Agents with a Beneficial Neuroprotective Profile against Alzheimer's DiseasePyka, Patryk; Haberek, Wawrzyniec; Wiecek, Malgorzata; Szymanska, Ewa; Ali, Wesam; Cios, Agnieszka; Jastrzebska-Wiesek, Magdalena; Satala, Grzegorz; Podlewska, Sabina; Di Giacomo, Silvia; Di Sotto, Antonella; Garbo, Sabrina; Karcz, Tadeusz; Lambona, Chiara; Marocco, Francesco; Latacz, Gniewomir; Sudol-Talaj, Sylwia; Mordyl, Barbara; Gluch-Lutwin, Monika; Siwek, Agata; Czarnota-Lydka, Kinga; Gogola, Dawid; Olejarz-Maciej, Agnieszka; Wilczynska-Zawal, Natalia; Honkisz-Orzechowska, Ewelina; Starek, Malgorzata; Dabrowska, Monika; Kucwaj-Brysz, Katarzyna; Fioravanti, Rossella; Nasim, Muhammad Jawad; Hittinger, Marius; Partyka, Anna; Wesolowska, Anna; Battistelli, Cecilia; Zwergel, Clemens; Handzlik, Jadwiga 分享 收藏 分享 收藏 Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer CellsZwergel, Clemens; Aventaggiato, Michele; Garbo, Sabrina; Di Bello, Elisabetta; Fassari, Bruno; Noce, Beatrice; Castiello, Carola; Lambona, Chiara; Barreca, Federica; Rotili, Dante; Fioravanti, Rossella; Schmalz, Thomas; Weyand, Michael; Niedermeier, Amelie; Tripodi, Marco; Colotti, Gianni; Steegborn, Clemens; Battistelli, Cecilia; Tafani, Marco; Valente, Sergio; Mai, Antonello 分享 收藏 
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