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Feng Ren

insilico medicine shanghai ltd.

29H指数
135论文数
3.0K被引数
收录论文 55
发表时间
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Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment将蛋白质组学衰老时钟整合到2a期临床试验中支持同步的抗衰老评估
errNature Biotechnology
IF41.7
err2026-09-07
err0
errOAAI
errAlex Zhavoronkov; Fedor Galkin; Shan Chen; Feng Ren; Alex Aliper; Mikhail Durymanov; Denis Sidorenko; Hui Cui; Jing-Dong J. Han; Hao Xu; Xiaodong Liu; Zuojun Xu; Christoph Kuppe; M. Austin Argentieri; Kejun Ying; Ludger J. E. Goeminne; Mahdi Moqri; Alexander Tyshkovskiy; Vadim N. Gladyshev
err分享
err收藏
Recent advance in macrocyclic CDK inhibitors近年来大环CDK抑制剂的最新进展
errFUTURE MEDICINAL CHEMISTRY
IF3.4
err2025-12-01
err0
PREAI
errZheng, Jiamin; Zhang, Zhisen; Liu, Jinxin; Shi, Ryan; Ren, Feng; Zhavoronkov, Alex; Ding, Xiao
err分享
err收藏
Design, Synthesis and Biological Evaluation of Novel, Potent, Selective and Orally Available DGKα Inhibitors for the Treatment of Tumors新型、高效、选择性且口服可用的DGKα抑制剂的 设计、合成及生物评价，用于肿瘤治疗
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-12-01
err0
PREAI
errLu, Hongfu; Shi, Sujing; Yu, Huaxing; Sun, Deheng; Zhang, Haoyu; Cui, Hui; Cai, Xin; Ding, Xiao; Chen, Shan; Zhang, Man; Liu, Jinxin; Shi, Ryan; Aliper, Alex; Ren, Feng; Zhavoronkov, Alex
err分享
err收藏
Discovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation人工智能赋能的双功能PKMYT1靶向PROTAC的发现
errNature Communications
IF15.7
err2025-11-28
err0
errOAAI
errYazhou Wang; Xiaomin Wang; Tingting Liu; Chao Wang; Qingshuo Meng; Fanye Meng; Jiaojiao Yu; Jinxin Liu; Yaya Fan; David Gennert; Frank W. Pun; Alex Aliper; Feng Ren; Man Zhang; Xin Cai; Xiao Ding; Alex Zhavoronkov
err分享
err收藏
Discovery and Biological Evaluation of Novel, Potent, and Orally Available CBLB Inhibitors新型、高效且口服可用的CBLB抑制剂的发现与生物活性评价
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-11-01
err0
PREAI
errMeng, Fanye; Cao, Zhongying; Liu, Jinxin; Wang, Yazhou; Ning, Zhilin; Yu, Jiaojiao; Fan, Yaya; Chen, Shan; Zhang, Man; Pun, Frank W.; Aliper, Alex; Ren, Feng; Cai, Xin; Ding, Xiao; Zhavoronkov, Alex
err分享
err收藏
Traf2- and Nck-interacting kinase inhibitors: a patent review (2008–2024)Traf2-和Nck相互作用激酶抑制剂的专利综述（2008–2024）
errExpert Opinion on Therapeutic Patents
IF4.6
err2025-08-20
err0
PREAI
errLuoheng Qin; Vladimir Aladinskiy; David Gennert; Xin Cheng; Jinxin Liu; Tingting Liu; Feng Ren; Alex Zhavoronkov
err分享
err收藏
Rational Design and Identification of ISM7594 as a Tissue-Agnostic FGFR2/3 Inhibitor理性设计与鉴定ISM7594作为组织泛用的FGFR2/3抑制剂
errJournal of Medicinal Chemistry
IF6.8
err2025-06-25
err0
PREAI
errYazhou Wang; Jinxin Liu; Yihong Zhang; Jichen Zhao; Chao Wang; Hui Cui; Fanye Meng; Alex Aliper; Tao Liang; Feng Yan; Feng Ren; Jiong Lan; Qiang Lu; Fusheng Zhou; Xin Cai; Xiao Ding; Alex Zhavoronkov
err分享
err收藏
Identification of Novel pan-KRAS Inhibitors via Structure-Based Drug Design; Scaffold Hopping; and Biological Evaluation基于结构的药物设计、骨架跳跃和生物评价鉴定新型泛KRAS抑制剂
errACS Medicinal Chemistry Letters
IF4
err2025-06-05
err0
PREAI
errVladimir Aladinskiy; Alexey B. Mantsyzov; Chris Kruse; Alexey Noev; Rostislav Petrov; Viktor Reshetnikov; Sujing Shi; Xiao Ding; Xin Cai; Alex Aliper; Alex Zhavoronkov; Feng Ren
err分享
err收藏
Oral ENPP1 inhibitor designed using generative AI as next generation STING modulator for solid tumors基于生成式AI设计的口服ENPP1抑制剂，作为下一代STING调节剂用于实体瘤。
errNATURE COMMUNICATIONS
IF15.7
err2025-05-23
err0
errOAAI
errPu, Congying; Cui, Hui; Yu, Huaxing; Cheng, Xin; Zhang, Man; Qin, Luoheng; Ning, Zhilin; Zhang, Wen; Chen, Shan; Qian, Yuhang; Wang, Feng; Wang, Ling; Lin, Xiaoxia; Gennert, David; Pun, Frank W.; Ren, Feng
err分享
err收藏
Discovery of Novel SIK2/3 Inhibitors for the Potential Treatment of MEF2C+Acute Myeloid Leukemia (AML)新型SIK2/3抑制剂的发现及其在MEF2C+急性髓系白血病(AML)潜在治疗中的应用
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-03-20
err0
PREAI
errZhu, Wei; Zhao, Pei; Liu, Tingting; Gao, Feng; Li, Qi; Cai, Xin; Zhang, Man; Aliper, Alex; Ren, Feng; Zhavoronkov, Alex
err分享
err收藏
Expanding the horizon of CAR T cell therapy: from cancer treatment to autoimmune diseases and beyond扩大CAR T细胞治疗的视野: 从癌症治疗到自身免疫性疾病及其他
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2025-02-19
err0
errOAAI
errYang, Zishan; Ha, Bingjun; Wu, Qinhan; Ren, Feng; Yin, Zhinan; Zhang, Hongru
err分享
err收藏
Discovery of Potent, Highly Selective, and Orally Bioavailable MTA Cooperative PRMT5 Inhibitors with Robust In Vivo Antitumor Activity发现具有强效、高度选择性及口服生物利用度的MTA协同PRMT5抑制剂，并展现出强大的体内抗肿瘤活性
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-01-09
err0
PREAI
errZhang, Meng; Ding, Xiaoyu; Cao, Zhongying; Yang, Yilin; Ding, Xiao; Cai, Xin; Zhang, Man; Aliper, Alex; Ren, Feng
err分享
err收藏
LLMs and AI Life Models for Traditional Chinese Medicine-derived Geroprotector FormulationLLMs和AI生命模型用于源自中医的抗衰老制剂
errAGING AND DISEASE
IF6.9
err2025-01-01
err0
errOAAI
errGalkin, F; Ren, F; Zhavoronkov, A
err分享
err收藏
Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancer
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2025-01-01
err0
PREAI
errWang, Chao; Wang, Yazhou; Meng, Fanye; Liu, Tingting; Wang, Xiaomin; Cai, Xin; Zhang, Man; Aliper, Alex; Ren, Feng; Zhavoronkov, Alex; Ding, Xiao
err分享
err收藏
Utilizing AI for the Identification and Validation of Novel Therapeutic Targets and Repurposed Drugs for Endometriosis利用人工智能鉴定和验证子宫内膜异位症的新治疗靶点和再利用药物
errADVANCED SCIENCE
IF14.1
err2024-12-12
err0
errOAAI
errLiu, Bonnie Hei Man; Lin, Yuezhen; Long, Xi; Hung, Sze Wan; Gaponova, Anna; Ren, Feng; Zhavoronkov, Alex; Pun, Frank W.; Wang, Chi Chiu
err分享
err收藏
Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitor
errNATURE BIOTECHNOLOGY
IF41.7
err2024-12-11
err0
errOAAI
errFu, Yanyun; Ding, Xiao; Zhang, Man; Feng, Chunlei; Yan, Ziqi; Wang, Feng; Xu, Jianyu; Lin, Xiaoxia; Ding, Xiaoyu; Wang, Ling; Fan, Yaya; Li, Taotao; Yin, Yushu; Liang, Xing; Xu, Chenxi; Chen, Shan; Pulous, Fadi E.; Gennert, David; Pun, Frank W.; Kamya, Petrina; Ren, Feng; Aliper, Alex; Zhavoronkov, Alex
err分享
err收藏
Roles of hypoxia-inducible factor-prolyl hydroxylases in aging and disease缺氧诱导因子脯氨酰羟化酶在衰老和疾病中的作用
errAGEING RESEARCH REVIEWS
IF12.4
err2024-12-01
err0
errOAAI
errGalkin, Fedor; Pulous, Fadi E.; Fu, Yanyun; Zhang, Man; Pun, Frank W.; Ren, Feng; Zhavoronkov, Alex
err分享
err收藏
Discovery of 1(2H)-phthalazinone and 1(2H)-isoquinolinone derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-12-01
err0
PREAI
errPeng, Jingjing; Ding, Xiaoyu; Shih, Pei-Yu; Meng, Qingyuan; Ding, Xiao; Zhang, Man; Aliper, Alex; Ren, Feng; Lu, Hongfu; Zhavoronkov, Alex
err分享
err收藏
Discovery of Pyridine-2-Carboxamides Derivatives as Potent and Selective HPK1 Inhibitors for the Treatment of Cancer
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-25
err0
PREAI
errPeng, Jingjing; Ding, Xiaoyu; Chen, Celia Xiaojing; Zhao, Pei; Ding, Xiao; Zhang, Man; Aliper, Alex; Ren, Feng; Lu, Hongfu; Zhavoronkov, Alex
err分享
err收藏
Discovery of a Novel Macrocyclic Noncovalent CDK7 Inhibitor for Cancer Therapy
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-09
err0
PREAI
errLu, Hongfu; Zhang, Yihong; Liu, Jinxin; Jiang, Tao; Yu, Xiang; Zhang, Haoyu; Liang, Tao; Peng, Jingjing; Cai, Xin; Lan, Xiaoling; Ren, Jinmin; Ge, Mei; Zhang, Jingyang; Shang, Jingjin; Yu, Jiaojiao; Ren, Hongcan; Liu, Qiang; Gao, Jinting; Tang, Lili; Ding, Xiao; Zhang, Man; Aliper, Alex; Lu, Qiang; Zhou, Fusheng; Lan, Jiong; Ren, Feng; Zhavoronkov, Alex
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
B
Ben Zhong Tang
H 指数: 212 · 论文数: 4.2K
王海龙 封面图
王海龙 (Hailong Wang)
H 指数: 124 · 论文数: 1.4K
V
Vadim N. Gladyshev
H 指数: 123 · 论文数: 789
A
Alán Aspuru‐Guzik
H 指数: 114 · 论文数: 938
J
Jeffrey D. Rothstein
H 指数: 108 · 论文数: 345
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