Timothy Haystead - Publications, H-index & Citations

Timothy Haystead

eydis bio inc.

63H指数

243论文数

1.5W被引数

收录论文 72

发表时间

Pharmacological inhibition of transforming growth factor-β activated kinase 1 (TAK1) prevents chemotherapy induced peripheral neuropathy (CIPN)药理学抑制转化生长因子-β激活激酶1（TAK1）可预防化疗诱导的周围神经病变（CIPN）。

the journal of pain

IF0

2026-03-31

OAAI

Timothy Haystead; Denise Giuvelis; Robert Freeze; Philip Hughes; Tamara King; Scott Scarneo

An Inhibitor of Death-Associated Protein Kinase 3 (DAPK3) Disrupts Hippo Signaling and Intestinal Epithelial Regeneration in Murine DSS-Induced Colitis 一种死亡相关蛋白激酶3（DAPK3）抑制剂破坏Hippo信号通路和在小鼠DSS诱导的结肠炎中的肠道上皮再生

Digestive Diseases and Sciences

IF2.5

2025-11-07

PREAI

Huey-Miin Chen; David A. Carlson; Timothy A. J. Haystead; Justin A. MacDonald

Mechanism of Impaired Protein Homeostasis in Kidney Grafts Following Cold Storage and Transplantation 冷储存和移植后肾移植物中蛋白质稳态受损的机制

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2025-03-01

PREAI

Lee, Seongok; Jun, Se-Ran; Venugopal, Gopinath; Arthur, John; Haystead, Timothy; Crow, Lee Ahn M.; Parajuli, Nirmala

TAK1 inhibition leads to RIPK1-dependent apoptosis in immune-activated cancers

CELL DEATH & DISEASE

IF9.6

2024-04-17

OAAI

Damhofer, Helene; Tatar, Tulin; Southgate, Benjamin; Scarneo, Scott; Agger, Karl; Shlyueva, Daria; Uhrbom, Lene; Morrison, Gillian M.; Hughes, Philip F.; Haystead, Timothy; Pollard, Steven M.; Helin, Kristian

Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome

CELL CHEMICAL BIOLOGY

IF7.2

2024-04-01

OAAI

Mansfield, Christopher R.; Quan, Baiyi; Chirgwin, Michael E.; Eduful, Benjamin; Hughes, Philip F.; Neveu, Gaeurolle; Sylvester, Kayla; Ryan, Daniel H.; Kafsack, Bjorn F. C.; Haystead, Timothy A. J.; Leahy, James W.; Fitzgerald, Michael C.; Derbyshire, Emily R.

Targeting Borrelia burgdorferi HtpG with a berserker molecule, a strategy for anti-microbial development

CELL CHEMICAL BIOLOGY

IF7.2

2024-03-01

OAAI

Carlson, Dave L.; Kowalewski, Mark; Bodoor, Khaldon; Lietzan, Adam D.; Hughes, Philip F.; Gooden, David; Loiselle, David R.; Alcorta, David; Dingman, Zoey; Mueller, Elizabeth A.; Irnov, Irnov; Modla, Shannon; Chaya, Tim; Caplan, Jeffrey; Embers, Monica; Miller, Jennifer C.; Jacobs-Wagner, Christine; Redinbo, Matthew R.; Spector, Neil; Haystead, Timothy A. J.

Investigation of SARS-CoV-2 individual proteins reveals the in vitro and in vivo immunogenicity of membrane protein

SCIENTIFIC REPORTS

IF3.9

2023-12-18

OAAI

Haystead, Timothy; Lee, Eric; Cho, Kirstin; Gullickson, Gail; Hughes, Philip; Krafsur, Greta; Freeze, Robert; Scarneo, Scott

Pharmacological inhibition of TAK1 prevents and induces regression of experimental organ fibrosis

JCI INSIGHT

IF6.1

2023-07-24

OAAI

Bale, Swarna; Verma, Priyanka; Yalavarthi, Bharath; Scarneo, Scott Arthur; Hughes, Philip; Amin, M. Asif; Tsou, Pei-Suen; Khanna, Dinesh; Haystead, Timothy A. J.; Bhattacharyya, Swati; Varga, John

Targeting the TAK1/TNF signaling pathway with novel pharmacological inhibitors

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2023-06-01

OAAI

Scarneo, Scott; Haystead, Timothy; Hughes, Philip; Freeze, Robert

Expression of membrane Hsp90 is a molecular signature of T cell activation

SCIENTIFIC REPORTS

IF3.9

2022-10-27

OAAI

Scarneo, Scott A.; Smith, Aaron P.; Favret, Jacob; O'Connell, Robert; Pickeral, Joy; Yang, Kelly W.; Ferrari, Guido; Loiselle, David R.; Hughes, Philip F.; Kulkarni, Manjusha M.; Gargesha, Madhusudhana; Scott, Bryan; Roy, Debashish; Haynes, Barton F.; Kwiek, Jesse J.; Haystead, Timothy A. J.

Mechanisms by which smoothelin-like protein 1 reverses insulin resistance in myotubules and mice smoothelin样蛋白1逆转肌小管和小鼠胰岛素抵抗的机制

MOLECULAR AND CELLULAR ENDOCRINOLOGY

IF3.6

2022-07-01

OAAI

Tamas, Istvan; Major, Evelin; Horvath, Daniel; Keller, Ilka; Ungvari, Adam; Haystead, Timothy A.; MacDonald, Justin A.; Lontay, Beata

Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis 用于治疗炎症性关节炎的口服生物利用度选择性TAK1抑制剂的开发和功效

ACS CHEMICAL BIOLOGY

IF3.8

2022-03-02

OAAI

Scarneo, Scott; Hughes, Philip; Freeze, Robert; Yang, Kelly; Totzke, Juliane; Haystead, Timothy

A bioorthogonal chemical reporter for fatty acid synthase-dependent protein acylation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-11-01

OAAI

Karthigeyan, Krithika P.; Zhang, Lizhi; Loiselle, David R.; Haystead, Timothy A. J.; Bhat, Menakshi; Yount, Jacob S.; Kwiek, Jesse J.

Expression of ectopic heat shock protein 90 in male and female primary afferent nociceptors regulates inflammatory pain

PAIN

IF5.5

2021-10-12

OAAI

Wang, Yaomin; Scarneo, Scott A.; Kim, Shin Hyung; Zhang, Xin; Chen, Jiegen; Yang, Kelly W.; Hughes, Philip; Haystead, Timothy; Nackley, Andrea G.

The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect

NATURE STRUCTURAL & MOLECULAR BIOLOGY

IF10.1

2021-08-11

OAAI

Woodford, Mark R.; Baker-Williams, Alexander J.; Sager, Rebecca A.; Backe, Sarah J.; Blanden, Adam R.; Hashmi, Fiza; Kancherla, Priyanka; Gori, Alessandro; Loiselle, David R.; Castelli, Matteo; Serapian, Stefano A.; Colombo, Giorgio; Haystead, Timothy A.; Jensen, Sandra M.; Stetler-Stevenson, William G.; Loh, Stewart N.; Schmidt, Laura S.; Linehan, W. Marston; Bah, Alaji; Bourboulia, Dimitra; Bratslavsky, Gennady; Mollapour, Mehdi

Transcription factor-driven alternative localization of Cryptococcus neoformans superoxide dismutase

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-01-01

OAAI

Smith, Aaron D.; Garcia-Santamarina, Sarela; Ralle, Martina; Loiselle, David R.; Haystead, Timothy A.; Thiele, Dennis J.

Targeting therapy-resistant prostate cancer via a direct inhibitor of the human heat shock transcription factor 1

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2020-12-16

OAAI

Dong, Bushu; Jaeger, Alex M.; Hughes, Philip F.; Loiselle, David R.; Hauck, J. Spencer; Fu, Yao; Haystead, Timothy A.; Huang, Jiaoti; Thiele, Dennis J.

Heat shock protein 90-targeted photodynamic therapy enables treatment of subcutaneous and visceral tumors

COMMUNICATIONS BIOLOGY

IF5.1

2020-05-08

OAAI

Kaneko, Kensuke; Osada, Takuya; Morse, Michael A.; Gwin, William R.; Ginzel, Joshua D.; Snyder, Joshua C.; Yang, Xiao-Yi; Liu, Cong-Xiao; Diniz, Marcio A.; Bodoor, Khaldon; Hughes, Philip F.; Haystead, Timothy A. J.; Lyerly, H. Kim

A highly selective inhibitor of interleukin-1 receptor?associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-02-01

OAAI

Scarneo, Scott A.; Hughes, Philip F.; Yang, Kelly W.; Carlson, David A.; Gurbani, Deepak; Westover, Kenneth D.; Haystead, Timothy A. J.

Copine A Interacts with Actin Filaments and Plays a Role in Chemotaxis and Adhesion

CELLS

IF5.2

2019-07-21

OAAI

Buccilli, Matthew J.; Ilacqua, April N.; Han, Mingxi; Banas, Andrew A.; Wight, Elise M.; Mao, Hanqian; Perry, Samantha P.; Salter, Tasha S.; Loiselle, David R.; Haystead, Timothy A. J.; Damer, Cynthia K.

研究方向