未登录 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics 透明质酸受体LYVE-1的结构及其介导白细胞进入淋巴管的特殊结合机制 Bano, Fouzia; Banerji, Suneale; Ni, Tao; Green, Dixy E.; Cook, Kalila R.; Manfield, Iain W.; Deangelis, Paul L.; Paci, Emanuele; Lepsik, Martin; Gilbert, Robert J. C. 分享 收藏
4-Oxo-β-lactams as Covalent Inhibitors of the Mitochondrial Intramembrane Protease PARL Ji, Shanping; Bach, Kathrin; Miriyala, Vijay Madhav; Dohnalek, Jan; Riopedre-Fernandez, Miguel; Lepsik, Martin; van de Plassche, Merel; Vanhoutte, Roeland; Barniol-Xicota, Marta; Moreira, Rui; Strisovsky, Kvido; Verhelst, Steven H. L. 分享 收藏
Extensive targeting of chemical space at the prime side of ketoamide inhibitors of rhomboid proteases by branched substituents empowers their selectivity and potency Bach, Kathrin; Dohnalek, Jan; Skerlova, Jana; Kuzmik, Jan; Polachova, Edita; Stanchev, Stancho; Majer, Pavel; Fanfrlik, Jindich; Pecina, Adam; Rezac, Jan; Lepsik, Martin; Borshchevskiy, Valentin; Polovinkin, Vitaly; Strisovsky, Kvido 分享 收藏
Structural insights into the interaction between adenovirus C5 hexon and human lactoferrin 腺病毒C5六邻体与人乳铁蛋白之间相互作用的结构见解 Dhillon, Arun; Persson, B. David; Volkov, Alexander N.; Sulzen, Hagen; Kadek, Alan; Pompach, Petr; Kereiche, Sami; Lepsik, Martin; Danskog, Katarina; Uetrecht, Charlotte; Arnberg, Niklas; Zoll, Sebastian 分享 收藏
分享 收藏
分享 收藏
分享 收藏
Powerful Avidity with a Limited Valency for Virus-Attachment Blockers on DC-SIGN: Combining Chelation and Statistical Rebinding with Structural Plasticity of the Receptor Porkolab, Vanessa; Lepsik, Martin; Ordanini, Stefania; St John, Alexander; Le Roy, Aline; Thepaut, Michel; Paci, Emanuele; Ebel, Christine; Bernardi, Anna; Fieschi, Franck 分享 收藏
Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes Benysek, Jakub; Busa, Michal; Rubesova, Petra; Fanfrlik, Jindrich; Lepsik, Martin; Brynda, Jiri; Matouskova, Zuzana; Bartz, Ulrike; Horn, Martin; Gutschow, Michael; Mares, Michael 分享 收藏
分享 收藏
3H-Pyrazolo[4,3-f]quinoline-Based Kinase Inhibitors Inhibit the Proliferation of Acute Myeloid Leukemia Cells In Vivo Dayal, Neetu; Reznickova, Eva; Hernandez, Delmis E.; Perina, Miroslav; Torregrosa-Allen, Sandra; Elzey, Bennett D.; Skerlova, Jana; Ajani, Haresh; Djukic, Stefan; Vojackova, Veronika; Lepsik, Martin; Rezacova, Pavlina; Krystof, Vladimir; Jorda, Radek; Sintim, Herman O. 分享 收藏
分享 收藏
Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni: Structural and Mechanistic Insights into Chemotype Reactivity Jilkova, Adela; Horn, Martin; Fanfrlik, Jindrich; Kueppers, Jim; Pachl, Petr; Rezacova, Pavlina; Lepsik, Martin; Fajtova, Pavla; Rubesova, Petra; Chanova, Marta; Caffrey, Conor R.; Guetschow, Michael; Mares, Michael 分享 收藏
Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors Jilkova, Adela; Rubesova, Petra; Fanfrlik, Jindrich; Fajtova, Pavla; Rezacova, Pavlina; Brynda, Jiri; Lepsik, Martin; Mertlikova-Kaiserova, Helena; Emal, Cory D.; Renslo, Adam R.; Roush, William R.; Horn, Martin; Caffrey, Conor R.; Mares, Michael 分享 收藏
Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis Houstecka, Radka; Hadzima, Martin; Fanfrlik, Jindrich; Brynda, Jiri; Pallova, Lenka; Hanova, Iva; Mertlikova-Kaiserova, Helena; Lepsik, Martin; Horn, Martin; Smrcina, Martin; Majer, Pavel; Mares, Michael 分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
