Shuying Yang - Publications, H-index & Citations

Shuying Yang

gsk, london, uk

22H指数

88论文数

1.7K被引数

收录论文 36

发表时间

Model-Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia 基于模型的新药研发支持在慢性肾病伴贫血患者中设计个体化给药方案（Daprodustat）

Clinical Pharmacology & Therapeutics

IF5.5

2025-10-31

OAAI

Kelly M. Mahar; Shuying Yang; Brendan Johnson; Sandra A.G. Visser; Paul van den Berg; Martijn van Noort; Teun M. Post

A Combined Model-Based Meta-Analysis of Aggregated and Individual FEV1 Data From Randomized COPD Trials 基于聚合和个体FEV1数据的随机COPD试验的联合模型化荟萃分析

cpt pharmacometrics systems pharmacology

IF0

2025-06-19

OAAI

Liang Yang; Carolina Llanos-Paez; Shuying Yang; Claire Ambery; Alienor Berges; Maria C. Kjellsson; Mats O. Karlsson

Integrated Longitudinal Population Dose-Hemoglobin Response of Daprodustat Following Dose Titration in Patients With Anemia in Chronic Kidney Disease

CLINICAL PHARMACOLOGY & THERAPEUTICS

IF5.5

2025-01-28

PREAI

Mahar, Kelly M.; van Noort, Martijn; van den Berg, Paul; Yang, Shuying; Visser, Sandra A. G.; Post, Teun M.

A simple, cost-effective, and efficient method for screening CRISPR/Cas9 mutants in plants

JOURNAL OF PLANT PHYSIOLOGY

IF4.1

2024-12-01

PREAI

Wang, Yiping; Ma, Jun; Wu, Yingying; Yang, Shuying; Wang, Pengxi; Zhang, Hailei; Li, Jitong; Chen, Lin; Kong, Weiwen; Xia, Yiji; Wang, Qiong; Liu, Jinglan

Inhibition of receptor interacting protein kinase-1 (RIPK1) in the treatment of murine lupus

LUPUS SCIENCE & MEDICINE

IF3.5

2024-06-21

OAAI

Peng, Lin; Wang, Pengcheng; Xu, Xiaodong; Chen, Dacheng; Xu, Feng; Yang, Fan; Yang, Shuying; Xia, Hongguang; Liu, Zhi-Hong; Qin, Weisong

Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway

CELL DEATH DISCOVERY

IF7

2022-04-01

OAAI

Ma, Xiao-Ru; Yang, Shu-Ying; Zheng, Shuang-Shuang; Yan, Huan-Huan; Gu, Hui-Min; Wang, Fan; Wu, Yang; Dong, Zhao-Jun; Wang, Di-Xian; Wang, Yue; Meng, Xianhui; Sun, Jie; Xia, Hong-Guang; Zhao, Jing-Wei

Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients

PHARMACEUTICAL RESEARCH

IF4.3

2022-03-01

OAAI

Llanos-Paez, Carolina; Ambery, Claire; Yang, Shuying; Beerahee, Misba; Plan, Elodie L.; Karlsson, Mats O.

Evaluation of area under the concentration curve adjusted by the terminal-phase as a metric to reduce the impact of variability in bioequivalence testing

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2021-08-24

OAAI

Lucas, Adam J.; Ogungbenro, Kayode; Yang, Shuying; Aarons, Leon; Chen, Chao

Improved Decision-Making Confidence Using Item-Based Pharmacometric Model: Illustration with a Phase II Placebo-Controlled Trial

AAPS JOURNAL

IF3.7

2021-06-02

OAAI

Llanos-Paez, Carolina; Ambery, Claire; Yang, Shuying; Tabberer, Maggie; Beerahee, Misba; Plan, Elodie L.; Karlsson, Mats O.

Detecting placebo and drug effects on Parkinson's disease symptoms by longitudinal item-score models

CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY

IF3

2021-05-05

OAAI

Chen, ChaoE; Jonsson, Siv; Yang, Shuying; Plan, Elodie L.; Karlsson, Mats O.

ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation ARIH1信号通过靶向PD-L1蛋白酶体降解促进抗肿瘤免疫

NATURE COMMUNICATIONS

IF15.7

2021-04-20

OAAI

Wu, Youqian; Zhang, Chao; Liu, Xiaolan; He, Zhengfu; Shan, Bing; Zeng, Qingxin; Zhao, Qingwei; Zhu, Huaying; Liao, Hongwei; Cen, Xufeng; Xu, Xiaoyan; Zhang, Mengmeng; Hou, Tingjun; Wang, Zhe; Yan, Huanhuan; Yang, Shuying; Sun, Yaqin; Chen, Yanying; Wu, Ronghai; Xie, Tingxue; Chen, Wei; Najafov, Ayaz; Ying, Songmin; Xia, Hongguang

Modelling item scores of Unified Parkinson's Disease Rating Scale Part III for greater trial efficiency

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2021-03-15

OAAI

Sheng, Yucheng; Zhou, Xuan; Yang, Shuying; Ma, Peiming; Chen, Chao

A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

IF4.5

2020-04-21

OAAI

Dumont, Etienne F.; Oliver, Amanda J.; Ioannou, Chris; Billiard, Julia; Dennison, Jeremy; van den Berg, Frans; Yang, Shuying; Chandrasekaran, Vijayalakshmi; Young, Graeme C.; Lahiry, Anirban; Starbuck, David C.; Harrell, Andrew W.; Georgiou, Alex; Hopchet, Nathalie; Gillies, Andy; Baker, Stephen J.

Item Response Model Adaptation for Analyzing Data from Different Versions of Parkinson's Disease Rating Scales

PHARMACEUTICAL RESEARCH

IF4.3

2019-07-17

OAAI

Gottipati, Gopichand; Berges, Alienor C.; Yang, Shuying; Chen, Chao; Karlsson, Mats O.; Plan, Elodie L.

A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT® Daily Diary Data from COPD Patients

AAPS JOURNAL

IF3.7

2019-04-26

OAAI

Germovsek, Eva; Ambery, Claire; Yang, Shuying; Beerahee, Misba; Karlsson, Mats O.; Plan, Elodie L.

A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis

EUROPEAN RESPIRATORY JOURNAL

IF21

2019-02-14

112

OAAI

Lukey, Pauline T.; Harrison, Stephen A.; Yang, Shuying; Man, Yim; Holman, Beverley F.; Rashidnasab, Alaleh; Azzopardi, Gabrielle; Grayer, Michael; Simpson, Juliet K.; Bareille, Philippe; Paul, Lyn; Woodcock, Hannah V.; Toshner, Richard; Saunders, Peter; Molyneaux, Philip L.; Thielemans, Kris; Wilson, Frederick J.; Mercer, Paul F.; Chambers, Rachel C.; Groves, Ashley M.; Fahy, William A.; Marshall, Richard P.; Maher, Toby M.

A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Crossover Study To Investigate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Repeat Doses of Inhaled Nemiralisib in Adults with Persistent, Uncontrolled Asthma

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

IF3.8

2018-12-01

OAAI

Khindri, Sanjeev; Cahn, Anthony; Begg, Malcolm; Montembault, Mickael; Leemereise, Claudia; Cui, Yi; Hogg, Annabel; Wajdner, Hannah; Yang, Shuying; Robertson, Jon; Hamblin, J. Nicole; Ludwig-Sengpiel, Andrea; Kornmann, Oliver; Hessel, Edith M.

MicroRNA-508 suppresses epithelial-mesenchymal transition, migration, and invasion of ovarian cancer cells through the MAPK1/ERK signaling pathway

JOURNAL OF CELLULAR BIOCHEMISTRY

IF2.8

2018-05-21

PREAI

Hong, Lan; Wang, Yifeng; Chen, Wangsheng; Yang, Shuying

Comparison of lipid profiles and inflammation in pre- and post-menopausal women with cerebral infarction and the role of atorvastatin in such populations

LIPIDS IN HEALTH AND DISEASE

IF4.2

2018-02-02

OAAI

Zhang, Jinhong; Wang, Hong; Yang, Shuying; Wang, Xiufen