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Enzo Tramontano

university of cagliari

50H指数
346论文数
7.0K被引数
收录论文 121
发表时间
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In silico-guided design, synthesis and in vitro evaluation of thiazolo-pyridines targeting SARS-CoV-2 Nsp13基于计算机模拟指导的设计、合成及体外评价靶向SARS-CoV-2 Nsp13的噻唑并吡啶类化合物
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-09-19
err0
errOAAI
errRoberta Bivacqua; Roberta Emmolo; Gianmarco Gualtieri; Simona Di Martino; Marilia Barreca; Virginia Spanò; Maria Valeria Raimondi; Angela Corona; Francesco Ortuso; Enzo Tramontano; Isabella Romeo; Alessandra Montalbano; Paola Barraja; Stefano Alcaro
err分享
err收藏
A Combination of MD Derived Pharmacophores and Structure-Based Strategy Identifies Dual Allosteric Inhibitors of NS2B-NS3 Proteases in Zika and West Nile Viruses结合MD衍生的药效团和基于结构的策略识别寨卡病毒和西尼罗病毒NS2B-NS3蛋白酶的双位点别构抑制剂
errEuropean Journal of Medicinal Chemistry
IF5.9
err2026-09-05
err0
PREAI
errAntonio Lupia; Salvatore Nieddu; Laura Demuru; Erica Sanna; Alessia Onali; Roberta Emmolo; Paolo Malune; Simona Distinto; Giulia Atzeni; Annalaura Paulis; Rita Meleddu; Filippo Cottiglia; Francesca Esposito; Angela Corona; Sharon D. Bryant; Elias Maccioni; Enzo Tramontano
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err收藏
Structure–Activity Relationships of Pyrrolyl-Containing Diketo Acid and Non-Diketo Acid Derivatives as Inhibitors of SARS-CoV-2 nsp13-Associated Activities含吡咯基的 diketo 酸和非 diketo 酸衍生物作为 SARS-CoV-2 nsp13 相关活性抑制剂的构效关系
errMolecules
IF4.6
err2026-08-16
err0
errOAAI
errElisa Patacchini; Francesco Saccoliti; Roberta Emmolo; Valentina Noemi Madia; Emanuele Cara; Aurora Albano; Angela Corona; Enzo Tramontano; Roberto Di Santo; Roberta Costi
err分享
err收藏
γ-Monoalkyl triphosphate analogues of acyclic nucleoside phosphonates inhibit SARS-CoV-2 replication in vitro by inducing dissociation of the minimal replication-transcription complex环状核苷磷酸酯的单烷基三磷酸类似物通过诱导最小复制-转录复合物的解离，在体外抑制SARS-CoV-2的复制
errAntiviral Research
IF4
err2026-08-01
err0
PREAI
errMalune, Paolo; Kullik, Giuliano; Jia, Xiao; Bandowski, Gyde; Esposito, Francesca; Lupia, Antonio; Distinto, Simona; Maccioni, Elias; Meier, Chris; Tramontano, Enzo
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err收藏
Report from the 9th Italian Society for Virology (SIV-ISV) 2025 Annual Meeting第九届意大利病毒学会（SIV-ISV）2025年度会议报告
errViruses
IF3.5
err2026-06-18
err0
errOAAI
errAnna De Filippis; Manuela Donalisio; Anna Luganini; Francesca Caccuri; Francesca Esposito; Nicole Grandi; Carla Zannella; Luisa Rubino; Enzo Tramontano; Gabriele Vaccari; Massimiliano Galdiero; Arnaldo Caruso
err分享
err收藏
2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase Inhibition2-苯基喹啉通过非结构蛋白13解旋酶抑制表现出抗严重急性呼吸综合征冠状病毒2活性
errChemMedChem
IF3.4
err2026-04-10
err0
errOAAI
errGiada Cernicchi; Maria Giulia Nizi; Roberta Emmolo; Leentje Persoons; Manon Laporte; Dirk Jochmans; Isabella Romeo; Giacomo Pepe; Ciro Milite; Pietro Campiglia; Jacopo Spezzini; Alma Martelli; Simone Brogi; Francesca Esposito; Tommaso Felicetti; Serena Massari; Giuseppe Manfroni; Stefano Sabatini; Gianluca Sbardella; Stefano Alcaro; Johan Neyts; Angela Corona; Enzo Tramontano; Steven De Jonghe; Oriana Tabarrini
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err收藏
Perceptions of care quality and human rights in Italian outpatient facilities during and after the pandemic疫情期间及之后意大利门诊机构中护理质量和人权的认知
errFrontiers in Public Health
IF3.4
err2026-04-08
err0
errOAAI
errEC Elisa Cantone; GK Goce Kalcev; MT Massimo Tusconi; AP Alessandra Perra; GF Gabriele Finco; CM Clelia Madeddu; LA Laura Atzori; EC Elisabetta Cotti; FB Fabrizio Bert; AP Antonio Preti; GL Giuseppe La Torre; MC Mauro Carzedda; OM Orsola Marra; FT Francesco Tomaso Muscas; VF Viviana Forte; SL Stefano Lorrai; CL Caterina La Cascia; LL Laura Loli Dano; ME Mehmet Eskin; FC Fatma Charfi; MA Michela Atzeni; ET Enzo Tramontano; GC Giulia Cossu; MG Mauro Giovanni Carta
err分享
err收藏
Design and Discovery of Substituted 1,3,4-Thiadiazole-1,3,5-Triazine Hybrids as Human Immunodeficiency Virus-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Anti-SARS-CoV-2 and Antibacterial Activities设计并发现取代的1,3,4-噻二唑-1,3,5-三嗪杂合物作为具有抗SARS-CoV-2和抗菌活性的人类免疫缺陷病毒-1非核苷类反转录酶抑制剂
errChemMedChem
IF3.4
err2026-03-27
err0
PREAI
errSingh, Saumya; Srivastava, Kumar Saurabh; Kumawat, Mukesh Kumar; Bhat, Hans Raj; Corona, Angela; Tramontano, Enzo; Mitra, Debashis; Singh, Udaya Pratap
err分享
err收藏
The role of hypothyroidism in the resilience against depressive episodes during covid pandemic in a cohort of old adults在新冠疫情期间，甲状腺功能减退症在老年人群中对抵抗抑郁发作的韧性中的作用
errFrontiers in Psychiatry
IF3.2
err2026-03-04
err0
errOAAI
errAP Alessandra Perra; MT Massimo Tusconi; EC Elisa Cantone; MA Michela Atzeni; ET Enzo Tramontano; SL Stefano Lorrai; FB Fabrizio Bert; AE Antonio E. Nardi; MG Mauro Giovanni Carta; GC Giulia Cossu
err分享
err收藏
Discovery of novel and potent non-nucleoside reverse transcriptase inhibitors through structure-based drug design for HIV treatment通过基于结构的药物设计发现新型且高效的HIV治疗非核苷类逆转录酶抑制剂
errChinese Chemical Letters
IF8.9
err2026-01-23
err0
PREAI
errYin-Xiang Zhang; Christophe Pannecouque; Erik De Clercq; Enzo Tramontano; Angela Corona; Laura Dettori; Phuong-Thao Tran; Xu-Dong Li; Shuo Su; Shuai Wang; Fen-Er Chen
err分享
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Scaffold hopping yields novel furo[3,2-d]pyrimidine NNRTIs with optimized antiviral potency, enhanced selectivity, and reduced hERG liability骨架跳跃获得具有优化抗病毒活性、增强选择性和降低hERG风险的 Novel furo[3,2-d]pyrimidine NNRTIs。
errActa Pharmaceutica Sinica B
IF14.6
err2026-01-14
err0
errOAAI
errYin-Xiang Zhang; Christophe Pannecouque; Erik De Clercq; Enzo Tramontano; Angela Corona; Laura Dettori; Phuong-Thao Tran; Xu-Dong Li; Shuo Su; Shuai Wang; Fen-Er Chen
err分享
err收藏
Cyclization-Inspired Structural Optimization: Designing Potent Non-nucleoside Reverse Transcriptase Inhibitors with Enhanced Safety and Selectivity
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2026-01-01
err0
PREAI
errZhang, Yin-Xiang; Pannecouque, Christophe; De Clercq, Erik; Tramontano, Enzo; Corona, Angela; Dettori, Laura; Tran, Phuong-Thao; Li, Xu-Dong; Su, Shuo; Wang, Shuai; Chen, Fen-Er
err分享
err收藏
2-(Trihydroxyphenyl)thienopyrimidinones as Key Scaffolds for Targeting a Novel Allosteric Site of HIV-1 Integrase2-(三羟基苯基)噻吩并嘧啶二酮作为靶向HIV-1整合酶新型别构位点的关键骨架
errMolecules 2025, Vol. 30, Page 4709
IF4.6
err2025-12-09
err0
errOAAI
errGraziella Tocco; Antonio Laus; Mattia Casula; Pierluigi Caboni; John A. Beutler; Enzo Tramontano; Francesca Esposito
err分享
err收藏
Suicidality and/or Death-Related Thoughts in Health Workers After Pandemics: The Role of DYMERS疫情后卫生工作者中的自杀倾向和/或与死亡相关的想法：DYMERS的作用
errJournal of Clinical Medicine 2025, Vol. 14, Page 8343
IF2.9
err2025-11-24
err0
errOAAI
errAntonio Urban; Elisa Cantone; Viviana Forte; Michela Atzeni; Stefano Lorrai; Mauro Carzedda; Gabriele Finco; Cesar Ivan Aviles Gonzalez; Sergio Machado; Roberta Montisci; Enzo Tramontano; Orsola Marra; Francesco Muscas; Fabrizio Bert; Giulia Cossu; Mauro Giovanni Carta
err分享
err收藏
N-alkyl and N-benzyl indoles are anti-SARS-CoV-2 agents and nsp13 inhibitorsN-烷基和N-苄基吲哚是抗SARS-CoV-2的药物，也是nsp13抑制剂。
errJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
err2025-08-12
err0
errOAAI
errAurora Albano; Roberta Emmolo; Riccardo De Santis; Elisa Patacchini; Valentina Noemi Madia; Stefania Maloccu; Davide Ialongo; Giuseppe Ruggieri; Merve Arpacioglu; Luigi Scipione; Francesco Saccoliti; Donatella Amatore; Giorgia Grilli; Florigio Lista; Francesca Esposito; Enzo Tramontano; Angela Corona; Roberto Di Santo; Roberta Costi
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err收藏
Halogenation-Driven Discovery of Halomethylene-Biphenyl-Diarylpyrimidines as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Improved Safety and PK Profiles卤代作用驱动的卤代亚甲基-联苯-二芳基嘧啶类化合物作为具有改善安全性和药代动力学特性的强效HIV-1非核苷类逆转录酶抑制剂的开发
errJournal of Medicinal Chemistry
IF6.8
err2025-07-26
err0
PREAI
errXiao-Mei Chen; Qian Xu; Christophe Pannecouque; Erik De Clercq; Enzo Tramontano; Phuong-Thao Tran; Shuai Wang; Fen-Er Chen
err分享
err收藏
Unveiling SARS-CoV-2's heart: role, structure and inhibition of SARS-CoV-2 RNA-dependent RNA polymerase揭示SARS-CoV-2的核心：SARS-CoV-2 RNA依赖性RNA聚合酶的作用、结构与抑制
errAntiviral Research
IF4
err2025-06-03
err0
errOAAI
errPaolo Malune; Francesca Esposito; Enzo Tramontano
err分享
err收藏
Rational structure-based design and optimization of next-generation biphenyl-piperidine-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors基于结构的理性设计和对下一代联苯-哌啶-三嗪衍生物的优化，作为强效非核苷类逆转录酶抑制剂
errChinese Chemical Letters
IF8.9
err2025-05-21
err0
PREAI
errKun Zhang; Li-Min Zhao; Tianhao Xing; Yueyue Bu; Qingyun Wang; Christophe Pannecouque; Erik De Clercq; Angela Corona; Laura Dettori; Enzo Tramontano; Shuai Wang; Fen-Er Chen
err分享
err收藏
Structure-Activity Relationships of New 1-Aryl-1H-Indole Derivatives as SARS-CoV-2 Nsp13 Inhibitors新1-芳基-1H-吲哚衍生物作为SARS-CoV-2 Nsp13抑制剂的构效关系
errCHEMMEDCHEM
IF3.4
err2025-05-20
err0
PREAI
errValentina Noemi Madia; Roberta Emmolo; Elisa Patacchini; Donatella Amatore; Stefania Maloccu; Davide Ialongo; Aurora Albano; Giuseppe Ruggieri; Emanuele Cara; Laura Zarbo; Antonella Messore; Riccardo De Santis; Alessandra Amoroso; Florigio Lista; Francesca Esposito; Enzo Tramontano; Angela Corona; Roberto Di Santo; Roberta Costi
err分享
err收藏
Design, Synthesis and Biological Evaluation of 3-Hydrazonoindolin-2-one Derivatives as Novel HIV-1 RNase H Inhibitors3-肼基酮基吲哚啉-2-酮衍生物的设计、合成及生物评价：作为新型HIV-1 RNase H抑制剂的探索
errMOLECULES
IF4.6
err2025-04-22
err0
errOAAI
errZhang, Yiying; Wang, Rao; Bu, Yueyue; Corona, Angela; Dettori, Laura; Tramontano, Enzo; Pannecouque, Christophe; De Clercq, Erik; Meng, Ge; Chen, Fen-Er
err分享
err收藏

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