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A

Alexander S. Hauser

University of Copenhagen
H指数:25
被引数:7,534

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Peptide ligand discovery of G protein-coupled receptors

G蛋白偶联受体肽配体的发现

Nature Reviews Methods Primers
IF56
2026-07-160
PRE
Julius Hermes; Marin Matic; Ho Yan Yeung; Qianru Jiang; Lauri Urvas; Elizaveta Korchevaya; Tomasz Stepniewski; Alexandre Murza; Jana Selent; Michael Freissmuth; Christian Heinis; Pierre-Luc Boudreault; Jens Carlsson; Tao Che; Helena Safavi-Hemami; Alexander S. Hauser; Christian W. Gruber
Ultra-large virtual screening unveils potent agonists of the neuromodulatory orphan receptor GPR139

超大规模虚拟筛选揭示了神经调节孤核受体GPR139的强效激动剂

Nature Communications
IF15.7
2025-12-090
OAAI
Israel Cabeza de Vaca; Boris Trapkov; Ling Shen; Duy Duc Vo; Xiaoqun Zhang; Yunting Yang; Mitra Pezeshki; Xuehan Zhang; Frida Bällgren; Aljona Saleh; Andrii V. Tarnovskiy; Dmytro S. Radchenko; Yurii S. Moroz; Hans Bräuner-Osborne; Per Svenningsson; Jan Kihlberg; Zhi-Jie Liu; Alexander Sebastian Hauser; Jens Carlsson
Membrane curvature association of amphipathic helix 8 drives constitutive endocytosis of GPCRs

两亲性螺旋8的膜曲率关联驱动G蛋白偶联受体(GPCRs)的组成性内吞。

Science Advances
IF12.5
2025-08-130
OA
Jan Hendrik Schmidt; Rasmus Herlo; Joscha Rombach; Andreas Haahr Larsen; Mikkel Stoklund; Mathias Perslev; Tommas Theiss Ehler Nielsen; Keenie Ayla Andersen; Carmen Klein Herenbrink; Matthew D. Lycas; Aske Lykke Ejdrup; Nikolaj Riis Christensen; Jan P. Christensen; Mootaz Salman; Freja Herborg; Ulrik Gether; Alexander Sebastian Hauser; Patricia Bassereau; David Perrais; Kenneth Lindegaard Madsen
The polypharmacology of psychedelics reveals multiple targets for potential therapeutics

致幻剂的药物多效性揭示了潜在治疗药物的多重靶点

Neuron
IF15
2025-07-180
PRE
Manish K. Jain; Ryan H. Gumpper; Samuel T. Slocum; Gavin P. Schmitz; Jakob S. Madsen; Tia A. Tummino; Carl-Mikael Suomivuori; Xi-Ping Huang; Laura Shub; Jeffrey F. DiBerto; Kuglae Kim; Chelsea DeLeon; Brain E. Krumm; Jonathan F. Fay; Michael Keiser; Alexander S. Hauser; Ron O. Dror; Brian Shoichet; David E. Gloriam; David E. Nichols; Bryan L. Roth
Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

GIPR遗传变异的表征揭示了 β-arrestin对代谢表型的贡献

NATURE METABOLISM
IF20.8
2024-06-139
OAAI
Kizilkaya, Husun S.; Sorensen, Kimmie V.; Madsen, Jakob S.; Lindquist, Peter; Douros, Jonathan D.; Bork-Jensen, Jette; Berghella, Alessandro; Gerlach, Peter A.; Gasbjerg, Laerke S.; Mokrosinski, Jacek; Mowery, Stephanie A.; Knerr, Patrick J.; Finan, Brian; Campbell, Jonathan E.; D'Alessio, David A.; Perez-Tilve, Diego; Faas, Felix; Mathiasen, Signe; Rungby, Jorgen; Sorensen, Henrik T.; Vaag, Allan; Nielsen, Jens S.; Holm, Jens-Christian; Lauenborg, Jeannet; Damm, Peter; Pedersen, Oluf; Linneberg, Allan; Hartmann, Bolette; Holst, Jens J.; Hansen, Torben; Wright, Shane C.; Lauschke, Volker M.; Grarup, Niels; Hauser, Alexander S.; Rosenkilde, Mette M.
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
NATURE COMMUNICATIONS
IF15.7
2023-10-0912
OAAI
Wright, Shane C.; Motso, Aikaterini; Koutsilieri, Stefania; Beusch, Christian M.; Sabatier, Pierre; Berghella, Alessandro; Blondel-Tepaz, Elodie; Mangenot, Kimberley; Pittarokoilis, Ioannis; Sismanoglou, Despoina-Christina; Le Gouill, Christian; Olsen, Jesper V.; Zubarev, Roman A.; Lambert, Nevin A.; Hauser, Alexander S.; Bouvier, Michel; Lauschke, Volker M.
Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

人类GLP-1受体中罕见的杂合功能缺失变异与心脏代谢表型无关

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
2023-05-265
OA
Melchiorsen, Josefine U.; Sorensen, Kimmie, V; Bork-Jensen, Jette; Kizilkaya, Husun S.; Gasbjerg, Laerke S.; Hauser, Alexander S.; Rungby, Jorgen; Sorensen, Henrik T.; Vaag, Allan; Nielsen, Jens S.; Pedersen, Oluf; Linneberg, Allan; Hartmann, Bolette; Gjesing, Anette P.; Holst, Jens J.; Hansen, Torben; Rosenkilde, Mette M.; Grarup, Niels

研究方向

暂未获取到该数据
D
David E. Gloriam
H 指数:48论文数:159被引数:1.4万
C
Christian Munk
H 指数:51论文数:151被引数:1.1万
H
Hans Bräuner‐Osborne
H 指数:56论文数:280被引数:1.1万
K
Kasper Harpsøe
H 指数:27论文数:72被引数:3,829
A
Albert J. Kooistra
H 指数:34论文数:82被引数:4,606
J
Jakob Sture Madsen
H 指数:7论文数:13被引数:363
I
Isberg, Vignir
H 指数:0论文数:1被引数:16
M
Michel Bouvier
H 指数:108论文数:812被引数:3.9万
M
Mette M. Rosenkilde
H 指数:64论文数:385被引数:1.6万
P
Peter Lindquist
H 指数:10论文数:21被引数:550