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李

李炜 (Wei Li)

fudan university
H指数:19
被引数:1,141

个人简介

任职于复旦大学药学院药物化学系，副教授。1998年至2002年于复旦大学药学院药学专业本科，2002年至2004年获药物化学硕士学位，2004年至2007年获药物化学博士学位。2007年至2016年任复旦大学药学院药物化学教研室讲师，2012年10月至2013年10月任Medicinal Chemistry Laboratory, Alcohol and Drug Abuse Research Center, McLean Hospital | Psychiatric affiliate of Harvard Medical School访问学者，2016年12月起任现职。

教育背景

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工作经历

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荣誉奖项

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Pharmacological Characterization of SLL-022CCP; a Selective κ-Opioid Receptor Agonist with Potent Antinociceptive Effects and Low Central Side Effects

SLL-022CCP的药理学表征：一种选择性κ-阿片受体激动剂，具有强效镇痛作用和低中枢副作用

ACS Omega
IF4.3
2026-06-040
OA
Jiang-Wen Gui; Jia-Wen Luo; Deng-Gao Zhang; Zhi-Wen Wang; Chao Zhang; Meng Sun; Jia-Qi Tan; Si-Yuan Tang; Shao-Liang Duan; Yu-Liang Lin; Min Liu; Li-Jin Feng; Li-Ming Shao; Jing-Gen Liu; Pan-Wen Liu; Wei Li; Yu-Jun Wang
Discovery, SAR, and molecular basis of (R)-1-((3R,4S)-3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-3-(3-fluorophenyl)-2-methylpropan-1-one as a novel potent analgesic

发现、构效关系及分子基础：(R)-1-((3R,4S)-3-((二甲氨基)甲基)-4-羟基-4-(3-甲氧基苯基)哌啶-1-基)-3-(3-氟苯基)-2-甲基丙烷-1-酮作为一种新型强效镇痛剂

Bioorganic & Medicinal Chemistry
IF3
2025-10-300
PRE
Xiaodi Xu; Haoran Zhu; Qingbo Shao; Baiyu Chen; Jing Lin; Yang Gao; Zhenzhou He; Wei Fu; Wei Li
Design, synthesis, and biological activity of novel para-substituted phenylamino and phenyl derivatives of northebaine as selective delta opioid receptor agonists

新型对位取代苯氨基和苯基诺阿普吗啡衍生物的设计、合成及其生物活性研究：作为选择性δ阿片受体激动剂

Bioorganic & Medicinal Chemistry
IF3
2025-08-280
PRE
Denggao Zhang; Jiangwen Gui; Linghui Kong; Chuyuan Hu; Xinmeng Kou; Biying Wang; Shaoliang Duan; Min Liu; Zixiang Li; Jiawen Luo; Siyuan Tang; Hui Xiao; Zeyi Du; Qiong Xie; Jinggen Liu; Liming Shao; Wei Fu; Yujun Wang; Wei Li
Structure–Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6; 14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists

N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6; 14-endoethano-四氢降吗啡烷类化合物的结构与活性关系研究：作为强效且选择性κ阿片受体激动剂

Journal of Medicinal Chemistry
IF6.8
2025-07-280
PRE
Linghui Kong; Songyu Yao; Denggao Zhang; Jiangwen Gui; Baiyu Chen; Min Liu; Siyuan Tang; Chuyuan Hu; Shaoliang Duan; Biying Wang; Zixiang Li; Yiquan Shen; Yingjie Lan; Xiaoning Liu; Zeyi Du; Zihan Liu; Qiong Xie; Anan Liu; Jingrui Chai; Jinggen Liu; Liming Shao; Wei Fu; Yujun Wang; Wei Li
Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-04-220
PRE
Li, Zixiang; Ye, Rufeng; He, Qian; Lu, Jiashuo; Sun, Yanting; Sun, Xiujian; Tang, Siyuan; Hu, Shuyang; Chai, Jingrui; Kong, Linghui; Liu, Xiaoning; Chen, Jing; Fang, Yun; Lan, Yingjie; Xie, Qiong; Liu, Jinggen; Shao, Liming; Fu, Wei; Wang, Yujun; Li, Wei

研究方向

阿片受体配基相关疾病诊断治疗多样性化合物库的构建中枢神经系统疾病治疗药物发现
付
付伟
H 指数:27论文数:141被引数:2,773
邵留 封面图
邵留
H 指数:71论文数:604被引数:1.7万
Q
Qiong Xie
H 指数:23论文数:136被引数:1,542
L
Linghui Kong
H 指数:7论文数:19被引数:110
Z
Zhuibai Qiu
H 指数:16论文数:79被引数:672
J
Jinggen Liu
H 指数:14论文数:48被引数:461
Z
Zixiang Li
H 指数:35论文数:205被引数:3,817
J
Jing‐Rui Chai
H 指数:10论文数:42被引数:266
刘
刘景根
H 指数:29论文数:107被引数:2,375
Y
Yujun Wang
H 指数:28论文数:100被引数:2,640