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L

Linghui Kong

fudan university
H指数:7
被引数:111

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Structure-Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6,14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists (vol 6, pg 15889, 2025)
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2025-12-010
PRE
Kong, Linghui; Yao, Songyu; Zhang, Denggao; Gui, Jiangwen; Chen, Baiyu; Liu, Min; Tang, Siyuan; Hu, Chuyuan; Duan, Shaoliang; Wang, Biying; Li, Zixiang; Shen, Yiquan; Lan, Yingjie; Liu, Xiaoning; Du, Zeyi; Liu, Zihan; Xie, Qiong; Liu, Anan; Chai, Jingrui; Liu, Jinggen; Shao, Liming; Fu, Wei; Wang, Yujun; Li, Wei
Design, synthesis, and biological activity of novel para-substituted phenylamino and phenyl derivatives of northebaine as selective delta opioid receptor agonists

新型对位取代苯氨基和苯基诺阿普吗啡衍生物的设计、合成及其生物活性研究：作为选择性δ阿片受体激动剂

Bioorganic & Medicinal Chemistry
IF3
2025-08-280
PRE
Denggao Zhang; Jiangwen Gui; Linghui Kong; Chuyuan Hu; Xinmeng Kou; Biying Wang; Shaoliang Duan; Min Liu; Zixiang Li; Jiawen Luo; Siyuan Tang; Hui Xiao; Zeyi Du; Qiong Xie; Jinggen Liu; Liming Shao; Wei Fu; Yujun Wang; Wei Li
Structure–Activity Relationship of N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6; 14-endoethano-tetrahydronorthebaines as Potent and Selective Kappa Opioid Receptor Agonists

N-Cyclopropylmethyl-7α-[para-(arylcarboxamido)phenyl]-6; 14-endoethano-四氢降吗啡烷类化合物的结构与活性关系研究：作为强效且选择性κ阿片受体激动剂

Journal of Medicinal Chemistry
IF6.8
2025-07-280
PRE
Linghui Kong; Songyu Yao; Denggao Zhang; Jiangwen Gui; Baiyu Chen; Min Liu; Siyuan Tang; Chuyuan Hu; Shaoliang Duan; Biying Wang; Zixiang Li; Yiquan Shen; Yingjie Lan; Xiaoning Liu; Zeyi Du; Zihan Liu; Qiong Xie; Anan Liu; Jingrui Chai; Jinggen Liu; Liming Shao; Wei Fu; Yujun Wang; Wei Li
Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-04-220
PRE
Li, Zixiang; Ye, Rufeng; He, Qian; Lu, Jiashuo; Sun, Yanting; Sun, Xiujian; Tang, Siyuan; Hu, Shuyang; Chai, Jingrui; Kong, Linghui; Liu, Xiaoning; Chen, Jing; Fang, Yun; Lan, Yingjie; Xie, Qiong; Liu, Jinggen; Shao, Liming; Fu, Wei; Wang, Yujun; Li, Wei
Discovery of a Highly Selective and Potent κ Opioid Receptor Agonist from N-Cyclopropylmethyl-7α-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-11-1815
PREAI
Xiao, Li; Wang, Yujun; Zhang, Mumei; Wu, Weiwei; Kong, Linghui; Ma, Yan; Xu, Xuejun; Liu, Xiao; He, Qian; Qian, Yuanyuan; Sun, Huijiao; Wu, Haihao; Lin, Cheng; Huang, Huoming; Ye, Rongrong; Jiang, Shuang; Ye, Ru-Feng; Yuan, Congmin; Fang, Shengyang; Xue, Dengqi; Yang, Xicheng; Chen, Hao; Zheng, Yilin; Yu, Linqian; Xie, Qiong; Zheng, Lan; Fu, Wei; Li, Wei; Qiu, Zhuibai; Liu, Jinggen; Shao, Liming
7β-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues
BIOORGANIC & MEDICINAL CHEMISTRY
IF3
2018-08-0110
PREAI
Sun, Hui-jiao; Wang, Yu-hua; Yuan, Cong-min; Kong, Ling-hui; Xu, Xue-jun; Wang, Yu-jun; Wu, Hai-hao; Lin, Cheng; Qian, Yuan-yuan; Huang, Huo-ming; Xiao, Li; Liu, Xiao; He, Qian; Fang, Sheng-yang; Xue, Deng-qi; Yang, Xi-cheng; Chen, Hao; Zheng, Yi-lin; Zheng, Lan; Yu, Lin-qian; Xie, Qiong; Fu, Wei; Li, Wei; Liu, Jing-gen; Qiu, Zhui-bai; Shao, Li-ming

研究方向

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Q
Qiong Xie
H 指数:23论文数:136被引数:1,565
李
李炜
H 指数:19论文数:103被引数:1,146
付
付伟
H 指数:27论文数:141被引数:2,793
邵留 封面图
邵留
H 指数:71论文数:604被引数:1.7万
Z
Zixiang Li
H 指数:35论文数:205被引数:3,894
J
Jinggen Liu
H 指数:14论文数:48被引数:469
S
Siyuan Tang
H 指数:7论文数:20被引数:101
J
Jing‐Rui Chai
H 指数:10论文数:42被引数:273
钱
钱和
H 指数:45论文数:384被引数:9,377
Z
Zhuibai Qiu
H 指数:16论文数:79被引数:673