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R

R. Luke Wiseman

The Scripps Research Institute
H指数:53
被引数:1.0万

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Pharmacological targeting of RIG-I can selectively activate the integrated stress response

药理学靶向RIG-I能够选择性激活整合应激反应。

Science Advances
IF12.5
2025-10-290
PRE
Caroline A. Cuoco; Wen Ren; Kelsey R. Baron; Sakina Gologo; Valerie Perea; Prakhyat Mathur; Prerona Bora; Amina Ta; Alan Chu; Rama Aldakhlallah; Derek Rhoades; Christian M. Cole; Ee Phie Tan; William C. Hou; Leonard Yoon; Xiaoyan Guo; Jessica D. Rosarda; Phil S. Baran; Martin Kampmann; Lakeisha Tillery; Kristen A. Johnson; Evan T. Powers; R. Luke Wiseman; Jeffery W. Kelly
Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4

肿瘤内缺氧通过慢性激活整合应激反应转录因子ATF4促进CD8+ T细胞功能障碍

Immunity
IF26.3
2025-09-250
OAAI
Coral del Mar Alicea Pauneto; Brian P. Riesenberg; Evelyn J. Gandy; Andrew S. Kennedy; Genevieve T. Clutton; Jessica W. Hem; Katie E. Hurst; Elizabeth G. Hunt; Jarred M. Green; Brian C. Miller; Steven P. Angus; Gary L. Johnson; Robert J. Esther; Jennifer L. Guerriero; Peng Gao; David R. Soto-Pantoja; Robert L. Ferris; Jennifer L. Modliszewski; Michael F. Coleman; H. Kay Chung; J. Justin Milner; Stergios J. Moschos; R. Luke Wiseman; Jessica E. Thaxton
Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B

XBP1s的激活减轻了蛋白质毒性型Charcot-Marie-Tooth 1B疾病模型中的疾病严重程度。

BRAIN
IF11.7
2025-02-211
OA
Touvier, Thierry; Veneri, Francesca A.; Claessens, Anke; Ferri, Cinzia; Mastrangelo, Rosa; Sorgiati, Noemie; Bianchi, Francesca; Valenzano, Serena; Del Carro, Ubaldo; Rivellini, Cristina; Duong, Phu; Shy, Michael E.; Kelly, Jeffery W.; Svaren, John; Wiseman, R. Luke; D'Antonio, Maurizio
S-lactoyl modification of KEAP1 by a reactive glycolytic metabolite activates NRF2 signaling

反应性糖酵解代谢物对KEAP1的S-乳酰修饰激活NRF2信号传导

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2023-05-0815
OAAI
Ko, Yeonjin; Hong, Mannkyu; Lee, Seungbeom; Kumar, Manoj; Ibrahim, Lara; Nutsch, Kayla; Stanton, Caroline; Sandoval, Braddock; Sondermann, Phillip; Bulos, Maya L.; Iaconelli, Jonathan; Chatterjee, Arnab K.; Wiseman, R. Luke; Schultz, Peter G.; Bollong, Michael J.

研究方向

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J
Jeffery W. Kelly
H 指数:119论文数:617被引数:5.2万
E
Evan T. Powers
H 指数:58论文数:162被引数:1.3万
J
Jessica D. Rosarda
H 指数:10论文数:22被引数:552
J
Joseph C. Genereux
H 指数:27论文数:67被引数:3,364
R
Ryan J Paxman
H 指数:11论文数:30被引数:1,043
M
Michael J. Bollong
H 指数:21论文数:86被引数:2,094
J
Julia M. D. Grandjean
H 指数:12论文数:24被引数:761
L
Lars Plate
H 指数:33论文数:185被引数:3,917
G
Gabriel C. Lander
H 指数:56论文数:264被引数:1.2万
L
Lisa M. Ryno
H 指数:10论文数:26被引数:1,397