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CTLA-4 blockade shifts the B cell repertoire toward autoimmunity CTLA-4阻断使B细胞库转向自身免疫。 Cakan, Elif; Wang, Meng; Dai, Yile; Mirouse, Adrien; Villanueva-Pachas, Clarence Rachel; Bouis, Delphine; Boeckers, Joshua M.; Gera, Ruchi; Yraita, Sally; Clapp, Leslie; Perdigoto, Ana Luisa; Delmotte, Fabien R.; Massad, Christopher; Bacchiocchi, Antonietta; Ring, Aaron M.; Kluger, Yuval; Kluger, Harriet M.; Herold, Kevan C.; Meffre, Eric 分享 收藏
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Circulating tumor-reactive KIR+CD8+ T cells suppress anti-tumor immunity in patients with melanoma 循环肿瘤反应性KIR CD8 T细胞抑制黑色素瘤患者的抗肿瘤免疫 Lu, Benjamin Y.; Lucca, Liliana E.; Lewis, Wesley; Wang, Jiping; Nogueira, Catarina V.; Heer, Sebastian; Rayon-Estrada, Violeta; Axisa, Pierre-Paul; Reeves, Sarah M.; Buitrago-Pocasangre, Nicholas C.; Pham, Giang H.; Kojima, Mina L.; Wei, Wei; Aizenbud, Lilach; Bacchiocchi, Antonietta; Zhang, Lin; Walewski, Joseph J.; Chiang, Veronica; Olino, Kelly; Clune, James; Halaban, Ruth; Kluger, Yuval; Coyle, Anthony J.; Kisielow, Jan; Obermair, Franz-Josef; Kluger, Harriet M.; Hafler, David A. 分享 收藏
The single-cell opioid responses in the context of HIV (SCORCH) consortium Ament, Seth A.; Campbell, Rianne R.; Lobo, Mary Kay; Receveur, Joseph P.; Agrawal, Kriti; Borjabad, Alejandra; Byrareddy, Siddappa N.; Chang, Linda; Clarke, Declan; Emani, Prashant; Gabuzda, Dana; Gaulton, Kyle J.; Giglio, Michelle; Giorgi, Federico M.; Gok, Busra; Guda, Chittibabu; Hadas, Eran; Herb, Brian R.; Hu, Wen; Huttner, Anita; Ishmam, Mohammad R.; Jacobs, Michelle M.; Kelschenbach, Jennifer; Kim, Dong-Wook; Lee, Cheyu; Liu, Shuhui; Liu, Xiaokun; Madras, Bertha K.; Mahurkar, Anup A.; Mash, Deborah C.; Mukamel, Eran A.; Niu, Meng; O'Connor, Richard M.; Pagan, Chelsea M.; Pang, Alina P. S.; Pillai, Piya; Repunte-Canonigo, Vez; Ruzicka, W. Brad; Stanley, Jay; Tickle, Timothy; Tsai, Shang-Yi A.; Wang, Allen; Wills, Lauren; Wilson, Alyssa M.; Wright, Susan N.; Xu, Siwei; Yang, Junchen; Zand, Maryam; Zhang, Le; Zhang, Jing; Akbarian, Schahram; Buch, Shilpa; Cheng, Christine S.; Corley, Michael J.; Fox, Howard S.; Gerstein, Mark; Gummuluru, Suryaram; Heiman, Myriam; Ho, Ya-Chi; Kellis, Manolis; Kenny, Paul J.; Kluger, Yuval; Milner, Teresa A.; Moore, David J.; Morgello, Susan; Ndhlovu, Lishomwa C.; Rana, Tariq M.; Sanna, Pietro Paolo; Satterlee, John S.; Sestan, Nenad; Spector, Stephen A.; Spudich, Serena; Tilgner, Hagen U.; Volsky, David J.; White, Owen R.; Williams, Dionne W.; Zeng, Hongkui 分享 收藏
HIV-1-infected T cell clones are shared across cerebrospinal fluid and blood during ART Wang, Meng; Yoon, Jennifer; Reisert, Hailey; Das, Bibhuprasad; Orlinick, Benjamin; Chiarella, Jennifer; Halvas, Elias K.; Mellors, John; Pang, Alina P. S.; Barakat, Lydia Aoun; Fikrig, Margaret; Cyktor, Joshua; Kluger, Yuval; Spudich, Serena; Corley, Michael J.; Farhadian, Shelli F. 分享 收藏
Gene trajectory inference for single-cell data by optimal transport metrics 通过最佳传输度量对单细胞数据进行基因轨迹推断 Qu, Rihao; Cheng, Xiuyuan; Sefik, Esen; Stanley, Jay S.; Landa, Boris; Strino, Francesco; Platt, Sarah; Garritano, James; Odell, Ian D.; Coifman, Ronald; Flavell, Richard A.; Myung, Peggy; Kluger, Yuval 分享 收藏
A novel humanized mouse model recapitulates the unique TME found in patients with HIV-associated NSCLC Juric, Melani; Kaufmann, Gabriel; Zhu, Li; Ranjan, Kishu; Agrawal, Kriti; Rajendran, Barani Kumar; Rajashekar, Jyothi K.; Zhao, Hongyu; Kluger, Yuval; Emu, Brinda; Schalper, Kurt A.; Kumar, Priti; Flavell, Richard A.; Chiorazzi, Michael 分享 收藏
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A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better Djureinovic, Dijana; Weiss, Sarah A.; Krykbaeva, Irina; Qu, Rihao; Vathiotis, Ioannis; Moutafi, Myrto; Zhang, Lin; Perdigoto, Ana L.; Wei, Wei; Anderson, Gail; Damsky, William; Hurwitz, Michael; Johnson, Barbara; Schoenfeld, David; Mahajan, Amit; Hsu, Frank; Miller-Jensen, Kathryn; Kluger, Yuval; Sznol, Mario; Kaech, Susan M.; Bosenberg, Marcus; Jilaveanu, Lucia B.; Kluger, Harriet M. 分享 收藏
Maternal CXCR4 deletion results in placental defects and pregnancy loss mediated by immune dysregulation Lyu, Fang; Burzynski, Chase; Fang, Yuan yuan; Tal, Aya; Chen, Alice Y.; Kisa, Jacqueline; Agrawal, Kriti; Kluger, Yuval; Taylor, Hugh S.; Tal, Reshef 分享 收藏
IL-6 trans-signaling in a humanized mouse model of scleroderma Odell, Ian D.; Agrawal, Kriti; Sefik, Esen; Odell, Anahi V.; Caves, Elizabeth; Kirkiles-Smith, Nancy C.; Horsley, Valerie; Hinchcliff, Monique; Pober, Jordan S.; Kluger, Yuval; Flavell, Richard A. 分享 收藏
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment 用于免疫肿瘤学的自体人源化PDX建模概括了人类肿瘤微环境的特征 Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan J.; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Juric, Melani; Henze, Laura A.; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Rolando; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, Karolina; Fields, Ryan C.; Flavell, Richard A. 分享 收藏
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Autologous humanized PDX modeling for immuno-oncology recapitulates the human tumor microenvironment Chiorazzi, Michael; Martinek, Jan; Krasnick, Bradley; Zheng, Yunjiang; Robbins, Keenan; Qu, Rihao; Kaufmann, Gabriel; Skidmore, Zachary; Henze, Laura; Brosecke, Frederic; Adonyi, Adam; Zhao, Jun; Shan, Liang; Sefik, Esen; Mudd, Jacqueline; Bi, Ye; Goedegebuure, S. Peter; Griffith, Malachi; Griffith, Obi; Oyedeji, Abimbola; Fertuzinhos, Sofia; Garcia-Milian, Roland; Boffa, Daniel; Detterbeck, Frank; Dhanasopon, Andrew; Blasberg, Justin; Judson, Benjamin; Gettinger, Scott; Politi, Katerina; Kluger, Yuval; Palucka, A. Karolina; Fields, Ryan; Flavell, Richard A. 分享 收藏
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