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Functional and structural polypharmacology of indazole-based privileged ligands to tackle the undruggability of membrane transporters Stefan, Katja; Puri, Sachin; Rafehi, Muhammad; Latambale, Ganesh; Neif, Maria; Taegl, Franziska; Arlt, Nike Sophia; Yazdi, Zeinab Nezafat; Bakos, Eva; Chen, Xiang; Zhang, Bohan; Al-Khalil, Wouroud Ismail; Busch, Hauke; Chen, Zhe-Sheng; Ozvegy-Laczka, Csilla; Namasivayam, Vigneshwaran; Juvale, Kapil; Stefan, Sven Marcel 分享 收藏
Discovery of Anthranilic Acid Derivatives as Antagonists of the Pro-Inflammatory Orphan G Protein-Coupled Receptor GPR17 Boshta, Nader M.; Lewash, Michael; Koese, Meryem; Namasivayam, Vigneshwaran; Sarkar, Soumya; Voss, Jan H.; Liedtke, Andy J.; Junker, Anna; Tian, Maoqun; Stoessel, Anne; Rashed, Mahmoud; Mahal, Ahmed; Merten, Nicole; Pegurier, Cecile; Hockemeyer, Jo''rg; Kostenis, Evi; Mueller, Christa E. 分享 收藏
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Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity Mahardhika, Andhika B.; Zaluski, Michal; Schoeder, Clara T.; Boshta, Nader M.; Schabikowski, Jakub; Perri, Filomena; Lazewska, Dorota; Neumann, Alexander; Kremers, Sarah; Oneto, Angelo; Ressemann, Anastasiia; Latacz, Gniewomir; Namasivayam, Vigneshwaran; Kiec-Kononowicz, Katarzyna; Mueller, Christa E. 分享 收藏
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Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4) Marx, Daniel; Alnouri, Mohamed Wessam; Clemens, Sophie; Gedschold, Robin; Riedel, Yvonne; Al Hamwi, Ghazl; Pillaiyar, Thanigaimalai; Hockemeyer, Jorg; Namasivayam, Vigneshwaran; Mueller, Christa E. 分享 收藏
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Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress Chipurupalli, Sandhya; Ganesan, Raja; Martini, Giulia; Mele, Luigi; Reggio, Alessio; Esposito, Marianna; Kannan, Elango; Namasivayam, Vigneshwaran; Grumati, Paolo; Desiderio, Vincenzo; Robinson, Nirmal 分享 收藏
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Unraveling binding mechanism and kinetics of macrocyclic Gαq protein inhibitors Voss, Jan H.; Nagel, Jessica; Rafehi, Muhammad; Guixa-Gonzalez, Ramon; Malfacini, Davide; Patt, Julian; Kehraus, Stefan; Inoue, Asuka; Koenig, Gabriele M.; Kostenis, Evi; Deupi, Xavier; Namasivayam, Vigneshwaran; Mueller, Christa E. 分享 收藏
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