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收藏Identification of potential glutaminyl cyclase inhibitors from lead-like libraries by in silico and in vitro fragment-based screening通过基于计算机和体外片段的筛选从铅样库中鉴定潜在的谷氨酰胺酰环化酶抑制剂
Szaszko, Maria; Hajdu, Istvan; Flachner, Beata; Dobi, Krisztina; Magyar, Csaba; Simon, Istvan; Lorincz, Zsolt; Kapui, Zoltan; Pazmany, Tamas; Cseh, Sandor; Dorman, Gyorgy
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收藏Combination of Pharmacophore Matching, 2D Similarity Search, and In Vitro Biological Assays in the Selection of Potential 5-HT6 Antagonists from Large Commercial Repositories结合药效团匹配,2D相似性搜索和体外生物学分析,从大型商业资料库中选择潜在的5-HT6拮抗剂
Dobi, Krisztina; Flachner, Beata; Pukancsik, Maria; Mathe, Eniko; Bognar, Melinda; Szaszko, Maria; Magyar, Csaba; Hajdu, Istvan; Lorincz, Zsolt; Simon, Istvan; Fueloep, Ferenc; Cseh, Sandor; Dorman, Gyoergy
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收藏Combination of 2D/3D Ligand-Based Similarity Search in Rapid Virtual Screening from Multimillion Compound Repositories. Selection and Biological Evaluation of Potential PDE4 and PDE5 Inhibitors基于2D/3D配体的相似性搜索在从数百万化合物库中快速虚拟筛选中的组合。潜在PDE4和PDE5抑制剂的筛选及生物学评价
Dobi, Krisztina; Hajdu, Istvan; Flachner, Beata; Fabo, Gabriella; Szaszko, Maria; Bognar, Melinda; Magyar, Csaba; Simon, Istvan; Szisz, Daniel; Lorincz, Zsolt; Cseh, Sandor; Dorman, Gyorgy
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