Gilles Labesse - Publications, H-index & Citations

Gilles Labesse

centre de biologie structurale (cbs)

45H指数

220论文数

6.4K被引数

收录论文 75

发表时间

Fragment-based drug design of a bacterial kinase inhibitor capable of increasing the antibiotic sensitivity of clinical isolates 基于片段的细菌激酶抑制剂药物设计，该抑制剂能够提高临床分离株的抗生素敏感性

Communications Chemistry

IF6.2

2025-11-27

OAAI

Julien Kowalewski; Robin Deutscher; Marion Richardoz; Mathilde Tomaszczyk; Muriel Gelin; Gilles Labesse; Felix Hausch; Gerard D. Wright; Catherine Dunyach-Remy; Jean-François Guichou; Corinne Lionne

APH Inhibitors that Reverse Aminoglycoside Resistance in Enterococcus casseliflavus

CHEMMEDCHEM

IF3.4

2025-01-26

PREAI

Kaplan, Elise; Chaloin, Laurent; Guichou, Jean-Francois; Berrou, Kevin; Rahimova, Rahila; Labesse, Gilles; Lionne, Corinne

SLiMAn 2.0: meaningful navigation through peptide-protein interaction networks

NUCLEIC ACIDS RESEARCH

IF13.1

2024-05-23

OAAI

Reys, Victor; Pons, Jean-Luc; Labesse, Gilles

Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events 细胞周期蛋白A/Cdk活性的增加和FAM122A对PP2A-B55的抑制是关键的有丝分裂诱导事件

EMBO JOURNAL

IF8.3

2024-02-20

OAAI

Lacroix, Benjamin; Vigneron, Suzanne; Labbe, Jean Claude; Pintard, Lionel; Lionne, Corinne; Labesse, Gilles; Castro, Anna; Lorca, Thierry

Characterization of the Mechanisms Controlling Greatwall Activity

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Vigneron, Suzanne; Gharbi-Ayachi, Aicha; Raymond, Anne-Aurelie; Burgess, Andrew; Labbe, Jean-Claude; Labesse, Gilles; Monsarrat, Bernard; Lorca, Thierry; Castro, Anna

Characterization of the Mechanisms Controlling Greatwall Activity (vol 31, pg 2262, 2011)

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Vigneron, Suzanne; Gharbi-Ayachi, Aicha; Raymond, Anne-Aurelie; Burges, Andrew; Labbe, Jean-Claude; Labesse, Gilles; Monsarrat, Bernard; Lorca, Thierry; Castro, Anna

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-01-01

OAAI

Clement, David A.; Gelin, Muriel; Leseigneur, Clarisse; Huteau, Valerie; Mondange, Lou; Pons, Jean-Luc; Dussurget, Olivier; Lionne, Corinne; Labesse, Gilles; Pochet, Sylvie

Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase

FEBS JOURNAL

IF4.2

2022-09-08

OAAI

Rahimova, Rahila; Nogaret, Pauline; Huteau, Valerie; Gelin, Muriel; Clement, David A.; Labesse, Gilles; Pochet, Sylvie; Blanc-Potard, Anne-Beatrice; Lionne, Corinne

Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation

MOLECULAR CELL

IF16.6

2022-09-01

OAAI

Mary, Charline; Soflaee, Mona Hoseini; Kesavan, Rushendhiran; Gelin, Muriel; Brown, Harrison; Zacharias, G.; Mathews, Thomas P.; Lemoff, Andrew; Lionne, Corinne; Labesse, Gilles; Hoxhaj, Gerta

SLiMAn: An Integrative Web Server for Exploring Short Linear Motif-Mediated Interactions in Interactomes SLiMAn: 一个集成的Web服务器，用于探索互动中的短线性主题介导的相互作用

JOURNAL OF PROTEOME RESEARCH

IF3.6

2022-06-01

OAAI

Reys, Victor; Labesse, Gilles

Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target

FEBS JOURNAL

IF4.2

2022-03-09

PREAI

Walter, Patrick; Mechaly, Ariel; Bous, Julien; Haouz, Ahmed; England, Patrick; Lai-Kee-Him, Josephine; Ancelin, Aurelie; Hoos, Sylviane; Baron, Bruno; Trapani, Stefano; Bron, Patrick; Labesse, Gilles; Munier-Lehmann, Helene

Structural evolution of the ancient enzyme, dissimilatory sulfite reductase 古老的酶，异化亚硫酸盐还原酶的结构进化

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

IF2.8

2022-02-18

OAAI

Colman, Daniel R.; Labesse, Gilles; Swapna, Gurla V. T.; Stefanakis, Johanna; Montelione, Gaetano T.; Boyd, Eric S.; Royer, Catherine A.

Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-12-27

OAAI

Schneider, Melanie; Delfosse, Vanessa; Gelin, Muriel; Grimaldi, Marina; Granell, Meritxell; Heriaud, Laurene; Pons, Jean-Luc; Gonsaud, Martin Cohen; Balaguer, Patrick; Bourguet, William; Labesse, Gilles

Retinitis Punctata Albescens and RLBP1-Allied Phenotypes Phenotype-Genotype Correlation and Natural History in the Aim of Gene Therapy

OPHTHALMOLOGY SCIENCE

IF4.6

2021-09-01

OAAI

Bocquet, Beatrice; Trebki, Hicham El Alami; Roux, Anne Francoise; Labesse, Gilles; Brabet, Philippe; Arndt, Carl; Zanlonghi, Xavier; Defoort-Dhellemmes, Sabine; Hamroun, Dalil; Boulicot-Seguin, Celine; Lequeux, Leopoldine; Picot, Marie Christine; Huguet, Helena; Audo, Isabelle; Dhaenens, Claire Marie; Kalatzis, Vasiliki; Meunier, Isabelle

The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop

NATURE COMMUNICATIONS

IF15.7

2021-06-11

OAAI

Labbe, Jean Claude; Vigneron, Suzanne; Mechali, Francisca; Robert, Perle; Roque, Sylvain; Genoud, Cindy; Goguet-Rubio, Perrine; Barthe, Phillipe; Labesse, Gilles; Cohen-Gonsaud, Martin; Castro, Anna; Lorca, Thierry

Proteo3Dnet: a web server for the integration of structural information with interactomics data

NUCLEIC ACIDS RESEARCH

IF13.1

2021-05-08

OAAI

Postic, Guillaume; Andreani, Jessica; Marcoux, Julien; Reyss, Victor; Guerois, Raphael; Rey, Julien; Mouton-Barbosa, Emmanuelle; Vandenbrouck, Yves; Cianferani, Sarah; Burlet-Schiltz, Odile; Labesse, Gilles; Tuffery, Pierre

The Dynamic Ion Motive Force Powering the Bacterial Flagellar Motor

FRONTIERS IN MICROBIOLOGY

IF4.5

2021-04-13

OAAI

Biquet-Bisquert, Anais; Labesse, Gilles; Pedaci, Francesco; Nord, Ashley L.

An oligomeric switch controls the Mrr-induced SOS response in E. coli 寡聚开关控制大肠杆菌中Mrr诱导的SOS反应

DNA REPAIR

IF2.7

2021-01-01

OAAI

Bourges, Anais C.; Montaguth, Oscar E. Torres; Tadesse, Wubishet; Labesse, Gilles; Aertsen, Abram; Royer, Catherine A.; Declerck, Nathalie

New Chemical Probe Targeting Bacterial NAD Kinase

MOLECULES

IF4.6

2020-10-22

OAAI

Clement, David A.; Leseigneur, Clarisse; Gelin, Muriel; Coelho, Dylan; Huteau, Valerie; Lionne, Corinne; Labesse, Gilles; Dussurget, Olivier; Pochet, Sylvie

Probing Protein Interaction Networks by Combining MS-Based Proteomics and Structural Data Integration

JOURNAL OF PROTEOME RESEARCH

IF3.6

2020-04-27

OAAI

Postic, Guillaume; Marcoux, Julien; Reys, Victor; Andreani, Jessica; Vandenbrouck, Yves; Bousquet, Marie-Pierre; Mouton-Barbosa, Emmanuelle; Cianferani, Sarah; Burlet-Schiltz, Odile; Guerois, Raphael; Labesse, Gilles; Tuffery, Pierre

研究方向