未登录 分享 收藏
分享 收藏
Design, synthesis, biophysical and biological evaluation of original condensed pyrrolopyrimidine and pyrrolopyridine ligands as anti-SARS-CoV-2 agents targeting G4 原始稠合吡咯并嘧啶和吡咯并吡啶配体的设计、合成及其作为靶向G4的抗SARS-CoV-2剂的生物物理和生物学评价 Guillon, Jean; Savrimoutou, Solene; Da Rocha, Nicolas; Albenque-Rubio, Sandra; Helynck, Olivier; Durand, Cyrielle; Chiaravalli, Jeanne; Pinaud, Noel; Ronga, Luisa; Moreau, Stephane; Chirold, Simon; Zangmo, Tshering; Arab, Melika; Lari, Lindita; Mergny, Jean-Louis; Munier-Lehmann, Helene; Lavigne, Marc 分享 收藏
分享 收藏
An equine iPSC-based phenotypic screening platform identifies pro- and anti-viral molecules against West Nile virus Cochet, Marielle; Piumi, Francois; Gorna, Kamila; Berry, Noemie; Gonzalez, Gaelle; Danckaert, Anne; Aulner, Nathalie; Blanchet, Odile; Zientara, Stephan; Donadeu, Francesc Xavier; Munier-Lehmann, Helene; Richardson, Jennifer; Benchoua, Alexandra; Coulpier, Muriel 分享 收藏
Modulation of the functional interfaces between retroviral intasomes and the human nucleosome Mauro, E.; Lapaillerie, D.; Tumiotto, C.; Charlier, C.; Martins, F.; Sousa, S. F.; Metifiot, M.; Weigel, P.; Yamatsugu, K.; Kanai, M.; Munier-Lehmann, H.; Richetta, C.; Maisch, M.; Dutrieux, J.; Batisse, J.; Ruff, M.; Delelis, O.; Lesbats, P.; Parissi, V. 分享 收藏
分享 收藏
Discovery of Bis-Imidazoline Derivatives as New CXCR4 Ligands Zhou, Zhicheng; Staropoli, Isabelle; Brelot, Anne; Suzanne, Peggy; Lesnard, Aurelien; Fontaine, Fanny; Perato, Serge; Rault, Sylvain; Helynck, Olivier; Arenzana-Seisdedos, Fernando; Santos, Jana Sopkova-de Oliveira; Lagane, Bernard; Munier-Lehmann, Helene; Colin, Philippe 分享 收藏
SigH stress response mediates killing of Mycobacterium tuberculosis by activating nitronaphthofuran prodrugs via induction of Mrx2 expression Cioetto-Mazzabo, Laura; Boldrin, Francesca; Beauvineau, Claire; Speth, Martin; Marina, Alberto; Namouchi, Amine; Segafreddo, Greta; Cimino, Mena; Favre-Rochex, Sandrine; Balasingham, Seetha; Trastoy, Beatriz; Munier-Lehmann, Helene; Griffiths, Gareth; Gicquel, Brigitte; Guerin, Marcelo E.; Manganelli, Riccardo; Alonso-Rodriguez, Noelia 分享 收藏
Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanism Magnotti, Flora; Chirita, Daria; Dalmon, Sarah; Martin, Amandine; Bronnec, Pauline; Sousa, Jeremy; Helynck, Olivier; Lee, Wonyong; Kastner, Daniel L.; Chae, Jae Jin; McDermott, Michael F.; Belot, Alexandre; Popoff, Michel; Seve, Pascal; Georgin-Lavialle, Sophie; Munier-Lehmann, Helene; Tu Anh Tran; De Langhe, Ellen; Wouters, Carine; Jamilloux, Yvan; Henry, Thomas 分享 收藏
Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target Walter, Patrick; Mechaly, Ariel; Bous, Julien; Haouz, Ahmed; England, Patrick; Lai-Kee-Him, Josephine; Ancelin, Aurelie; Hoos, Sylviane; Baron, Bruno; Trapani, Stefano; Bron, Patrick; Labesse, Gilles; Munier-Lehmann, Helene 分享 收藏
Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors Song, Lijun; Merceron, Romain; Hulpia, Fabian; Lucia, Ainhoa; Gracia, Begona; Jian, Yanlin; Risseeuw, Martijn D. P.; Verstraelen, Toon; Cos, Paul; Ainsa, Jose A.; Boshoff, Helena, I; Munier-Lehmann, Helene; Savvides, Savvas N.; Van Calenbergh, Serge 分享 收藏
SARS-CoV-2 Nsp3 unique domain SUD interacts with guanine quadruplexes and G4-ligands inhibit this interaction Lavigne, Marc; Helynck, Olivier; Rigolet, Pascal; Boudria-Souilah, Rofia; Nowakowski, Mireille; Baron, Bruno; Brule, Sebastien; Hoos, Sylviane; Raynal, Bertrand; Guittat, Lionel; Beauvineau, Claire; Petres, Stephane; Granzhan, Anton; Guillon, Jean; Pratviel, Genevieve; Teulade-Fichou, Marie-Paule; England, Patrick; Mergny, Jean-Louis; Munier-Lehmann, Helene 分享 收藏
分享 收藏
Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents Jian, Yanlin; Merceron, Romain; De Munck, Steven; Forbes, He Eun; Hulpia, Fabian; Risseeuw, Martijn D. P.; Van Hecke, Kristof; Savvides, Savvas N.; Munier-Lehmann, Helene; Boshoff, Helena. I. M.; Van Calenbergh, Serge 分享 收藏
分享 收藏
A real-time cell-binding assay reveals dynamic features of STxB-Gb3 cointernalization and STxB-mediated cargo delivery into cancer cells Encarnacao, Joao; Napolitano, Valeria; Opassi, Giulia; Danielson, U. Helena; Dubin, Grzegorz; Popowicz, Grzegorz M.; Munier-Lehmann, Helene; Buijs, Jos; Andersson, Karl; Bjorkelund, Hanna 分享 收藏
Replication of Equine arteritis virus is efficiently suppressed by purine and pyrimidine biosynthesis inhibitors 嘌呤和嘧啶生物合成抑制剂可有效抑制马动脉炎病毒的复制 Valle-Casuso, Jose-Carlos; Gaudaire, Delphine; Martin-Faivre, Lydie; Madeline, Anthony; Dallemagne, Patrick; Pronost, Stephane; Munier-Lehmann, Helene; Zientara, Stephan; Vidalain, Pierre-Olivier; Hans, Aymeric 分享 收藏
分享 收藏
分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
