John M. Essigmann - Publications, H-index & Citations

John M. Essigmann

massachusetts institute of technology

66H指数

236论文数

1.5W被引数

收录论文 86

发表时间

Sex and base excision repair as key susceptibility factors for alkylation-induced mutations, toxicity and hepatic cancer 性别和碱基切除修复作为烷基化诱导突变、毒性和肝细胞癌的关键易感因素

DNA Repair

IF2.7

2026-08-04

OAAI

Jennifer E. Kay; Joshua J. Corrigan; Lindsay B. Volk; Amanda L. Armijo; Norah A. Owiti; Lee J. Pribyl; Ilana S. Nazari; Dorothea K. Torous; Svetlana L. Avlasevich; Robert G. Croy; Dushan N. Wadduwage; Sebastian E. Carrasco; Stephen D. Dertinger; John M. Essigmann; Leona D. Samson; Bevin P. Engelward

Fluorescent Detection of Aqueous N-Nitrosodimethylamine via Photochemical Transformation and Affinity Capture 通过光化学转化和亲和捕获对水相N-亚硝基二甲胺进行荧光检测

Journal of the American Chemical Society

IF15.6

2026-07-09

OAAI

Chi-Hsien Wang; Hsuan-Min Hung; Robert G. Croy; John M. Essigmann; Bradley L. Pentelute; Timothy M. Swager

TOXINS

IF4

2025-02-27

OAAI

Thongararm, Pennapa; Chancharoen, Marisa; Suwanwong, Nutchapong; Ruchirawat, Somsak; Ruchirawat, Mathuros; Fedeles, Bogdan I.; Croy, Robert G.; Essigmann, John M.

Stable Interstrand Cross-Links Generated from the Repair of 1,N6-Ethenoadenine in DNA by α-Ketoglutarate/Fe(II)-Dependent Dioxygenase ALKBH2

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-04-04

OAAI

Wang, Jie; Takyi, Nathania A.; Hsiao, Yun-Chung; Tang, Qi; Chen, Yi-Tzai; Liu, Chih-Wei; Ma, Jian; Qi, Rui; Bian, Ke; Peng, Zhiyuan; Essigmann, John M.; Lu, Kun; Wetmore, Stacey D.; Li, Deyu

5-Chloro-2′-deoxycytidine Induces a Distinctive High-Resolution Mutational Spectrum of Transition Mutations In Vivo

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2024-02-23

OAAI

Chancharoen, Marisa; Yang, Zhiyu; Dalvie, Esha D.; Gubina, Nina; Ruchirawat, Mathuros; Croy, Robert G.; Fedeles, Bogdan I.; Essigmann, John M.

A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress 合成剂通过增加氧化应激促进囊性细胞凋亡来改善多囊肾病

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-01-19

OAAI

Fedeles, Bogdan I.; Bhardwaj, Rishi; Ishikawa, Yasunobu; Khumsubdee, Sakunchai; Krappitz, Matteus; Gubina, Nina; Volpe, Isabel; Andrade, Denise C.; Westergerling, Parisa; Staudner, Tobias; Campolo, Jake; Liu, Sally S.; Dong, Ke; Cai, Yiqiang; Rehman, Michael; Gallagher, Anna-Rachel; Ruchirawat, Somsak; Croy, Robert G.; Essigmann, John M.; V. Fedeles, Sorin; Somlo, Stefan

Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents

NAR CANCER

IF3.2

2023-03-27

OAAI

Armijo, Amanda L.; Thongararm, Pennapa; Fedeles, Bogdan, I; Yau, Judy; Kay, Jennifer E.; Corrigan, Joshua J.; Chancharoen, Marisa; Chawanthayatham, Supawadee; Samson, Leona D.; Carrasco, Sebastian E.; Engelward, Bevin P.; Fox, James G.; Croy, Robert G.; Essigmann, John M.

Interaction of N-nitrosamines with binuclear copper complexes for luminescent detection

DALTON TRANSACTIONS

IF3.3

2023-01-01

OAAI

Feng, Haosheng; Luo, Shao-Xiong Lennon; Croy, Robert G.; Essigmann, John M.; Swager, Timothy M.

Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2022-07-26

OAAI

Basu, Ashis K.; Essigmann, John M.

7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli

NUCLEIC ACIDS RESEARCH

IF13.1

2022-03-02

OAAI

Aralov, Andrey, V; Gubina, Nina; Cabrero, Cristina; Tsvetkov, Vladimir B.; Turaev, Anton, V; Fedeles, Bogdan, I; Croy, Robert G.; Isaakova, Ekaterina A.; Melnik, Denis; Dukova, Svetlana; Ryazantsev, Dmitriy Y.; Khrulev, Alexei A.; Varizhuk, Anna M.; Gonzalez, Carlos; Zatsepin, Timofei S.; Essigmann, John M.

Metallocalix[4]arene Polymers for Gravimetric Detection of N-Nitrosodialkylamines

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2021-11-18

OAAI

Lu, Ru-Qiang; Yuan, Weize; Croy, Robert G.; Essigmann, John M.; Swager, Timothy M.

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

CELL REPORTS

IF6.9

2021-03-01

OAAI

Kay, Jennifer E.; Corrigan, Joshua J.; Armijo, Amanda L.; Nazari, Ilana S.; Kohale, Ishwar N.; Torous, Dorothea K.; Avlasevich, Svetlana L.; Croy, Robert G.; Wadduwage, Dushan N.; Carrasco, Sebastian E.; Dertinger, Stephen D.; White, Forest M.; Essigmann, John M.; Samson, Leona D.; Engelward, Bevin P.

Modulation of N-Methyl-N-nitrosourea Mutagenesis in Mouse Embryo Fibroblasts Derived from the gpt Delta Mouse by an Inhibitor of the O6-Methylguanine Methyltransferase, MGMT

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2019-12-16

OAAI

Thongararm, Pennapa; Fedeles, Bogdan, I; Khumsubdee, Sakunchai; Armijo, Amanda L.; Kim, Lina; Thiantanawat, Apinya; Promvijit, Jeerawan; Navasumrit, Panida; Ruchirawat, Mathuros; Croy, Robert G.; Essigmann, John M.

DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro

NUCLEIC ACIDS RESEARCH

IF13.1

2019-05-22

OAAI

Bian, Ke; Lenz, Stefan A. P.; Tang, Qi; Chen, Fangyi; Qi, Rui; Jost, Marco; Drennan, Catherine L.; Essigmann, John M.; Wetmore, Stacey D.; Li, Deyu

Mutagenicity of Helicobacter hepaticus infection in the lower bowel mucosa of 129/SvEv Rag2-/-Il10-/- gpt delta mice is influenced by sex

INTERNATIONAL JOURNAL OF CANCER

IF4.7

2019-05-07

OAAI

Ge, Zhongming; Feng, Yan; Sheh, Alexander; Muthupalani, Sureshkumar; Gong, Guanyu; Chawanthayatham, Supawadee; Essigmann, John M.; Fox, James G.

Impact of DNA lesion repair, replication and formation on the mutational spectra of environmental carcinogens: Aflatoxin B1 as a case study

DNA REPAIR

IF2.7

2018-11-01

OAAI

Fedeles, Bogdan, I; Essigmann, John M.

An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2018-02-01

OAAI

Tajai, Preechaya; Fedeles, Bogdan I.; Suriyo, Tawit; Navasumrit, Panida; Kanitwithayanun, Jantamas; Essigmann, John M.; Satayavivad, Jutamaad

Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver 编辑亮点: 怀孕改变黄曲霉毒素B1代谢并增加小鼠肝脏的DNA损伤

TOXICOLOGICAL SCIENCES

IF4.1

2017-08-24

OAAI

Sriwattanapong, Kanokwan; Slocum, Stephen L.; Chawanthayatham, Supawadee; Fedeles, Bogdan I.; Egner, Patricia A.; Groopman, John D.; Satayavivad, Jutamaad; Croy, Robert G.; Essigmann, John M.

Mutation spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellualr carcinoma

CANCER RESEARCH

IF16.6

2017-07-01

PREAI

Chawanthayatham, Supawadee; Valentine, Charles C., III; Fedeles, Bogdan I.; Slocum, Stephen L.; Wogan, Gerald N.; Croy, Robert G.; Essigmann, John M.

1,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication Backgrounds

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2017-04-17

OAAI

Chang, Shiou-chi; Seneviratne, Uthpala I.; Wu, Jie; Tretyakova, Natalia; Essigmann, John M.

研究方向