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Stéphane Poulain

the university of tokyo

H指数:13

被引数:534

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Palmitic acid induced the onset of lipotoxicity in a HepaSH-on-chip model with raised of H2O2 and IL-6, and altered p38/MAPK & JAK/STAT pathways

棕榈酸在HepaSH-on-chip模型中诱导了脂毒性，伴随H2O2和IL-6水平升高，并改变了p38/MAPK和JAK/STAT通路。

IF4.6

2025-11-220

PRE

3D hepatic spheroids and liver-organ on chip models displayed maintenance of hepatic functions and maturation profile in a long-term culture of the humanized HepaSH cells, a human cell population harvested from chimeric mice

3D肝细胞球体和肝器官芯片模型显示，在长期培养的人类化HepaSH细胞（一种从嵌合小鼠中获取的人类细胞群）中，保持了肝功能维持和成熟表型。

Biotechnology Progress

IF2.5

2025-05-310

PRE

Transcriptomic characterization of the synergy between human induced pluripotent stem cells-derived liver- and pancreas-on-chip coculture

人诱导多能干细胞衍生的肝脏-和胰腺-芯片共培养的转录组学表征及其协同作用

Molecular and Cellular Endocrinology

IF3.6

2025-05-210

PRE

Dynamic, IPSC-derived hepatic tissue tri-culture system for the evaluation of liver physiology in vitro

IF8

2024-03-250

PRE

Mechanobiological stimulation in organ-on-a-chip systems reduces hepatic drug metabolic capacity in favor of regenerative specialization

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2024-01-071

PRE

Transcriptomic and proteomic studies suggest the establishment of advanced zonation-like profiles in human-induced pluripotent stem cell-derived liver sinusoidal endothelial cells and carboxypeptidase M-positive liver progenitor cells cocultured in a fluidic microenvironment

HEPATOLOGY RESEARCH

IF3.4

2023-04-022

PRE

Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids

MOLECULAR OMICS

IF2.4

2023-01-012

OA

Analysis of the transcriptome and metabolome of pancreatic spheroids derived from human induced pluripotent stem cells and matured in an organ-on-a-chip

MOLECULAR OMICS

IF2.4

2022-01-013

OA

Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment

APL BIOENGINEERING

IF4.1

2021-05-1012

OAAI

Multi-omics analysis of hiPSCs-derived HLCs matured on-chip revealed patterns typical of liver regeneration

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2021-02-079

PREAI

Integration of metabolomic and transcriptomic profiles of hiPSCs-derived hepatocytes in a microfluidic environment

BIOCHEMICAL ENGINEERING JOURNAL

IF3.8

2020-03-014

PREAI

Machine-driven parameter screen of biochemical reactions

NUCLEIC ACIDS RESEARCH

IF13.1

2020-02-060

OAAI

Transcriptome profiling of hiPSC-derived LSECs with nanoCAGE

MOLECULAR OMICS

IF2.4

2020-01-0113

OAAI

Integration of metabolomic and transcriptomic profiling to compare two protocols of differentiation of human induced pluripotent stem cells into hepatocytes

PROCESS BIOCHEMISTRY

IF4

2020-01-012

OAAI

Optimized protocol for the hepatic differentiation of induced pluripotent stem cells in a fluidic microenvironment

BIOTECHNOLOGY AND BIOENGINEERING

IF3.6

2019-03-2930

PREAI

Profiling of derived-hepatocyte progenitors from induced pluripotent stem cells using nanoCAGE promoter analysis

BIOCHEMICAL ENGINEERING JOURNAL

IF3.8

2019-02-019

PREAI

Analysis of the transcription factors and their regulatory roles during a step-by-step differentiation of induced pluripotent stem cells into hepatocyte-like cells

MOLECULAR OMICS

IF2.4

2019-01-019

OAAI

Discovery and characterization of new transcripts from RNA-seq data in mouse CD4+ T cells

IF3

2012-11-0114

OAAI

Signalling with retinoids in the human lung: validation of new tools for the expression study of retinoid receptors

IF3.4

2009-12-0410

OAAI

The synthesis, photophysical properties and energy transfer of a coumarin-based bichromophoric compound

DYES AND PIGMENTS

IF4.2

2009-01-017

PREAI