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H

Hans Gaus

ionis pharmaceuticals inc., 2855 gazelle ct., carlsbad, california 92010, united states
H指数:38
被引数:4,819

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Conjugation to a transferrin receptor 1-binding Bicycle peptide enhances ASO and siRNA potency in skeletal and cardiac muscles

与转铁蛋白受体1结合的Bicycle肽偶联可增强ASO和siRNA在骨骼肌和心肌中的效力

NUCLEIC ACIDS RESEARCH
IF13.1
2025-04-100
PRE
Ostergaard, Michael E.; Carrer, Michele; Anderson, Brooke A.; Afetian, Megan; Bakooshli, Mohsen A.; Santos, Jinro A.; Klein, Stephanie K.; Capitanio, Juliana; Freestone, Graeme C.; Tanowitz, Michael; Galindo-Murillo, Rodrigo; Gaus, Hans J.; Dwyer, Chrissa A.; Jackson, Michaela; Jafar-nejad, Paymaan; Rigo, Frank; Seth, Punit P.; Gaynor, Katherine U.; Stanway, Steven J.; Urbonas, Liudvikas; St. Denis, Megan A.; Pellegrino, Simone; Bezerra, Gustavo A.; Rigby, Michael; Gowans, Ellen; Van Rietschoten, Katerine; Beswick, Paul; Skynner, Michael J.; Swayze, Eric E.
Sequence-specific 2′-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates
HAEMATOLOGICA
IF7.9
2021-02-118
OAAI
Slingsby, Martina H. Lundberg; Vijey, Prakrith; Tsai, I-Ting; Roweth, Harvey; Couldwell, Genevieve; Wilkie, Adrian R.; Gaus, Hans; Goolsby, Jazana M.; Okazaki, Ross; Terkovich, Brooke E.; Semple, John W.; Thon, Jonathan N.; Henry, Scott P.; Narayanan, Padmakumar; Italiano, Joseph E., Jr.
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates
NUCLEIC ACIDS RESEARCH
IF13.1
2019-05-1182
OAAI
Ostergaard, Michael E.; Jackson, Michaela; Low, Audrey; Chappell, Alfred E.; Lee, Richard G.; Peralta, Rachel Q.; Yu, Jinghua; Kinberger, Garth A.; Dan, Amy; Carty, Rick; Tanowitz, Michael; Anderson, Patrick; Kim, Tae-Won; Fradkin, Linda; Mullick, Adam E.; Murray, Sue; Rigo, Frank; Prakash, Thazha P.; Bennett, C. Frank; Swayze, Eric E.; Gaus, Hans J.; Seth, Punit P.
Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins
NUCLEIC ACIDS RESEARCH
IF13.1
2019-04-2978
OAAI
Migawa, Michael T.; Shen, Wen; Wan, W. Brad; Vasquez, Guillermo; Oestergaard, Michael E.; Low, Audrey; De Hoyos, Cheryl L.; Gupta, Ruchi; Murray, Susan; Tanowitz, Michael; Bell, Melanie; Nichols, Joshua G.; Gaus, Hans; Liang, Xue-hai; Swayze, Eric E.; Crooke, Stanley T.; Seth, Punit P.
Comprehensive Structure-Activity Relationship of Triantennary N-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2016-03-09133
PREAI
Prakash, Thazha P.; Yu, Jinghua; Migawa, Michael T.; Kinberger, Garth A.; Wan, W. Brad; Ostergaard, Michael E.; Carty, Recaldo L.; Vasquez, Guillermo; Low, Audrey; Chappell, Alfred; Schmidt, Karsten; Aghajan, Mariam; Crosby, Jeff; Murray, Heather M.; Booten, Sheri L.; Hsiao, Jill; Soriano, Armand; Machemer, Todd; Cauntay, Patrick; Burel, Sebastien A.; Murray, Susan F.; Gaus, Hans; Graham, Mark J.; Swayze, Eric E.; Seth, Punit P.

研究方向

暂未获取到该数据
E
Eric E. Swayze
H 指数:61论文数:254被引数:1.4万
P
Punit P. Seth
H 指数:50论文数:166被引数:8,373
T
Thazha P. Prakash
H 指数:51论文数:144被引数:8,174
M
Michael T. Migawa
H 指数:29论文数:61被引数:3,412
A
Andrés Berdeja
H 指数:17论文数:40被引数:1,731
A
Alfred E. Chappell
H 指数:24论文数:37被引数:2,782
M
Michael E. Østergaard
H 指数:28论文数:63被引数:2,868
G
Garth A. Kinberger
H 指数:20论文数:55被引数:2,036
A
Audrey Low
H 指数:24论文数:39被引数:2,752
于京华 封面图
于京华
H 指数:84论文数:705被引数:3.0万