Erik Chorell - Publications, H-index & Citations

Erik Chorell

umea university

28H指数

77论文数

2.5K被引数

收录论文 38

发表时间

Dual Recognition Drives Site-Directed G-Quadruplex Stabilization: Exploring Oligonucleotide Design in G4 Ligand-Oligonucleotide Conjugates

Molecular Therapy Nucleic Acids

IF6.1

2026-08-14

OAAI

Alva Abrahamsson; Sakina Khwaja; Namrata Chaudhari; Steven Vertueux; Andreas Berner; Koit Aasumets; Chandan Kumar; Lotte Stietz; Tom Baladi; Anders Dahlén; Sjoerd Wanrooij; Erik Chorell

Tuning potency for precision: the role of the G4-ligand in G4-ligand conjugated oligonucleotides targeting individual G-quadruplex DNA structures 调控效力以实现精准性：G4配体在靶向特定G-四链体DNA结构的G4配体共轭寡核苷酸中的作用

RSC Chemical Biology

IF3.1

2026-02-01

OAAI

Abrahamsson, Alva; Khwaja, Sakina; Berner, Andreas; Nath Das, Rabindra; Aasumets, Koit; Chaudhari, Namrata; Wanrooij, Sjoerd; Chorell, Erik

Phosphate triester-based multifunctional handles for post-synthetic oligonucleotide functionalization 基于磷酸三酯的多功能基团用于后合成寡核苷酸功能化

BIOORGANIC CHEMISTRY

IF4.7

2025-04-01

OAAI

Golebiewska-Pikula, Justyna; Abrahamsson, Alva; Chorell, Erik

Linker Design Principles for the Precision Targeting of Oncogenic G-Quadruplex DNA with G4-Ligand-Conjugated Oligonucleotides

BIOCONJUGATE CHEMISTRY

IF3.9

2025-03-01

OAAI

Abrahamsson, Alva; Berner, Andreas; Golebiewska-Pikula, Justyna; Chaudhari, Namrata; Keskitalo, Emelie; Lindgren, Cecilia; Chmielewski, Marcin K.; Wanrooij, Sjoerd; Chorell, Erik

Design, Synthesis, and Biophysical Characterization of Pyridine Bis-Quinazoline Derivatives as Selective G-Quadruplex DNA Stabilizers

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2025-02-24

PREAI

Das, Rabindra Nath; Chorell, Erik

G4-Ligand-Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2024-03-02

OAAI

Berner, Andreas; Das, Rabindra Nath; Bhuma, Naresh; Golebiewska, Justyna; Abrahamsson, Alva; Andreasson, Mans; Chaudhari, Namrata; Doimo, Mara; Bose, Partha Pratim; Chand, Karam; Stromberg, Roger; Wanrooij, Sjoerd; Chorell, Erik

Exploring the Dispersion and Electrostatic Components in Arene-Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-01-19

OAAI

Andreasson, Mans; Donzel, Maxime; Abrahamsson, Alva; Berner, Andreas; Doimo, Mara; Quiroga, Anna; Eriksson, Anna; Chao, Yu-Kai; Overman, Jeroen; Pemberton, Nils; Wanrooij, Sjoerd; Chorell, Erik

Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells

NUCLEIC ACIDS RESEARCH

IF13.1

2023-06-23

OAAI

Doimo, Mara; Chaudhari, Namrata; Abrahamsson, Sanna; L'Hote, Valentin; Nguyen, Tran V. H.; Berner, Andreas; Ndi, Mama; Abrahamsson, Alva; Das, Rabindra Nath; Aasumets, Koit; Goffart, Steffi; Pohjoismaki, Jaakko L. O.; Lopez, Marcela Davila; Chorell, Erik; Wanrooij, Sjoerd

The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2023-02-01

OAAI

Bhuma, Naresh; Chand, Karam; Andreasson, Mans; Mason, James; Das, Rabindra Nath; Patel, Ankit Kumar; Ohlund, Daniel; Chorell, Erik

Using Macrocyclic G-Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G-Quadruplex DNA

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2022-09-19

OAAI

Andreasson, Mans; Bhuma, Naresh; Pemberton, Nils; Chorell, Erik

A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells

CHEMICAL SCIENCE

IF7.4

2022-01-01

OAAI

Prasad, Bagineni; Doimo, Mara; Andreasson, Mans; L'Hote, Valentin; Chorell, Erik; Wanrooij, Sjoerd

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures

ACS CHEMICAL BIOLOGY

IF3.8

2021-07-30

OAAI

Deiana, Marco; Obi, Ikenna; Andreasson, Mans; Tamilselvi, Shanmugam; Chand, Karam; Chorell, Erik; Sabouri, Nasim

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

NUCLEIC ACIDS RESEARCH

IF13.1

2020-10-12

OAAI

Obi, Ikenna; Rentoft, Matilda; Singh, Vandana; Jamroskovic, Jan; Chand, Karam; Chorell, Erik; Westerlund, Fredrik; Sabouri, Nasim

The Relation Between Position and Chemical Composition of Bis-Indole Substituents Determines Their Interactions with G-Quadruplex DNA

CHEMISTRY-A EUROPEAN JOURNAL

IF3.7

2020-07-03

OAAI

Prasad, Bagineni; Das, Rabindra Nath; Jamroskovic, Jan; Kumar, Rajendra; Hedenstrom, Mattias; Sabouri, Nasim; Chorell, Erik

Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

IF15.6

2020-01-28

OAAI

Jamroskovic, Jan; Doimo, Mara; Chand, Karam; Obi, Ikenna; Kumar, Rajendra; Brannstrom, Kristoffer; Hedenstrom, Mattias; Das, Rabindra Nath; Akhunzianov, Almaz; Deiana, Marco; Kasho, Kazutoshi; Sato, Sebastian Sulis; Pourbozorgi, Parham L.; Mason, James E.; Medini, Paolo; Ohlund, Daniel; Wanrooij, Sjoerd; Chorell, Erik; Sabouri, Nasim

Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes

NUCLEIC ACIDS RESEARCH

IF13.1

2020-01-08

OAAI

Kumar, Rajendra; Chand, Karam; Bhowmik, Sudipta; Das, Rabindra Nath; Bhattacharjee, Snehasish; Hedenstrom, Mattias; Chorell, Erik

A site-specific self-assembled light-up rotor probe for selective recognition and stabilization ofc-MYCG-quadruplex DNA

NANOSCALE

IF5.1

2020-01-01

OAAI

Deiana, Marco; Chand, Karam; Jamroskovic, Jan; Das, Rabindra Nath; Obi, Ikenna; Chorell, Erik; Sabouri, Nasim

Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Das, Rabindra Nath; Andreasson, Mans; Kumar, Rajendra; Chorell, Erik

Identification of putative G-quadruplex DNA structures in S. pombe genome by quantitative PCR stop assay 通过定量PCR停止分析鉴定S. pombe基因组中推定的G-四链体DNA结构

DNA REPAIR

IF2.7

2019-10-01

OAAI

Jamroskovic, Jan; Obi, Ikenna; Movahedi, Anahita; Chand, Karam; Chorell, Erik; Sabouri, Nasim

Chemical disarming of isoniazid resistance in Mycobacterium tuberculosis 结核分枝杆菌异烟肼耐药性的化学解除

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-05-06

OAAI

Flentie, Kelly; Harrison, Gregory A.; Tukenmez, Hasan; Livny, Jonathan; Good, James A. D.; Sarkar, Souvik; Zhu, Dennis X.; Kinsella, Rachel L.; Weiss, Leslie A.; Solomon, Samantha D.; Schene, Miranda E.; Hansen, Mette R.; Cairns, Andrew G.; Kulen, Martina; Wixe, Torbjorn; Lindgren, Anders E. G.; Chorell, Erik; Bengtsson, Christoffer; Krishnan, K. Syam; Hultgren, Scott J.; Larsson, Christer; Almqvist, Fredrik; Stallings, Christina L.

研究方向