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Samah El Ghamrasni

University of Toronto
H指数:17
被引数:1,464

个人简介

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教育背景

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工作经历

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荣誉奖项

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RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells

XRN2的RNF8泛素化促进R环解析并抑制BRCA1突变细胞中的基因组不稳定性

NUCLEIC ACIDS RESEARCH
IF13.1
2023-09-117
OAAI
Krishnan, Rehna; Lapierre, Mariah; Gautreau, Brandon; Nixon, Kevin C. J.; El Ghamrasni, Samah; Patel, Parasvi S.; Hao, Jun; Yerlici, V. Talya; Guturi, Kiran Kumar Naidu; St-Germain, Jonathan; Mateo, Francesca; Saad, Amine; Algouneh, Arash; Earnshaw, Rebecca; Shili, Duan; Seitova, Alma; Miller, Joshua; Khosraviani, Negin; Penn, Adam; Ho, Brandon; Sanchez, Otto; Hande, M. Prakash; Masson, Jean-Yves; Brown, Grant W.; Alaoui-Jamali, Moulay; Reynolds, John J.; Arrowsmith, Cheryl; Raught, Brian; Pujana, Miguel A.; Mekhail, Karim; Stewart, Grant S.; Hakem, Anne; Hakem, Razqallah
The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

纺锤体组装检查点是具有有丝分裂畸变的CDK4/6抑制剂抗性ER乳腺癌的治疗脆弱性

SCIENCE ADVANCES
IF12.5
2022-09-0921
OAAI
Soria-Bretones, Isabel; Thu, Kelsie L.; Silvester, Jennifer; Cruickshank, Jennifer; El Ghamrasni, Samah; Ba-alawi, Wail; Fletcher, Graham C.; Kiarash, Reza; Elliott, Mitchell J.; Chalmers, Jordan J.; Elia, Andrea C.; Cheng, Albert; Rose, April A. N.; Bray, Mark R.; Haibe-Kains, Benjamin; Mak, Tak W.; Cescon, David W.
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape (July, 10.1038/s41467-021-24348-6, 2021)
NATURE COMMUNICATIONS
IF15.7
2022-07-270
OAAI
Bruce, Jeff P.; To, Ka-Fai; Lui, Vivian W. Y.; Chung, Grace T. Y.; Chan, Yuk-Yu; Tsang, Chi Man; Yip, Kevin Y.; Ma, Brigette B. Y.; Woo, John K. S.; Hui, Edwin P.; Mak, Michael K. F.; Lee, Sau-Dan; Chow, Chit; Velapasamy, Sharmila; Or, Yvonne Y. Y.; Siu, Pui Kei; El Ghamrasni, Samah; Prokopec, Stephenie; Wu, Man; Kwan, Johnny S. H.; Liu, Yuchen; Chan, Jason Y. K.; van Hasselt, C. Andrew; Young, Lawrence S.; Dawson, Christopher W.; Paterson, Ian C.; Yap, Lee-Fah; Tsao, Sai-Wah; Liu, Fei-Fei; Chan, Anthony T. C.; Pugh, Trevor J.; Lo, Kwok-Wai
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity
NATURE COMMUNICATIONS
IF15.7
2021-08-2665
OAAI
Yang, S. Y. Cindy; Lien, Scott C.; Wang, Ben X.; Clouthier, Derek L.; Hanna, Youstina; Cirlan, Iulia; Zhu, Kelsey; Bruce, Jeffrey P.; El Ghamrasni, Samah; Iafolla, Marco A. J.; Oliva, Marc; Hansen, Aaron R.; Spreafico, Anna; Bedard, Philippe L.; Lheureux, Stephanie; Razak, Albiruni; Speers, Vanessa; Berman, Hal K.; Aleshin, Alexey; Haibe-Kains, Benjamin; Brooks, David G.; McGaha, Tracy L.; Butler, Marcus O.; Bratman, Scott, V; Ohashi, Pamela S.; Siu, Lillian L.; Pugh, Trevor J.
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape

鼻咽癌的全基因组分析揭示了炎性nf-κb激活和免疫逃逸中的病毒-宿主合作

NATURE COMMUNICATIONS
IF15.7
2021-07-0765
OAAI
Bruce, Jeff P.; To, Ka-Fai; Lui, Vivian W. Y.; Chung, Grace T. Y.; Chan, Yuk-Yu; Tsang, Chi Man; Yip, Kevin Y.; Ma, Brigette B. Y.; Woo, John K. S.; Hui, Edwin P.; Mak, Michael K. F.; Lee, Sau-Dan; Chow, Chit; Velapasamy, Sharmila; Or, Yvonne Y. Y.; Siu, Pui Kei; El Ghamrasni, Samah; Prokopec, Stephenie; Wu, Man; Kwan, Johnny S. H.; Liu, Yuchen; Chan, Jason Y. K.; van Hasselt, C. Andrew; Young, Lawrence S.; Dawson, Christopher W.; Paterson, Ian C.; Yap, Lee-Fah; Tsao, Sai-Wah; Liu, Fei-Fei; Chan, Anthony T. C.; Pugh, Trevor J.; Lo, Kwok-Wai
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors

RNF168调节BRCA1/2缺陷肿瘤的R环分辨率和基因组稳定性

JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-02-0142
OA
Patel, Parasvi S.; Abraham, Karan Joshua; Guturi, Kiran Kumar Naidu; Halaby, Marie-Jo; Khan, Zahra; Palomero, Luis; Ho, Brandon; Duan, Shili; St-Germain, Jonathan; Algouneh, Arash; Mateo, Francesca; El Ghamrasni, Samah; Barbour, Haithem; Barnes, Daniel R.; Beesley, Jonathan; Sanchez, Otto; Berman, Hal K.; Brown, Grant W.; Affar, El Bachir; Chenevix-Trench, Georgia; Antoniou, Antonis C.; Arrowsmith, Cheryl H.; Raught, Brian; Pujana, Miquel Angel; Mekhail, Karim; Hakem, Anne; Hakem, Razqallah
Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor

着丝粒内聚失败引起了胰腺神经内分泌肿瘤中染色体误分离的保守编排

GENOME MEDICINE
IF11.2
2020-04-2812
OAAI
Quevedo, Rene; Spreafico, Anna; Bruce, Jeff; Danesh, Arnavaz; El Ghamrasni, Samah; Giesler, Amanda; Hanna, Youstina; Have, Cherry; Li, Tiantian; Yang, S. Y. Cindy; Zhang, Tong; Asa, Sylvia L.; Haibe-Kains, Benjamin; Krzyzanowska, Monika; Smith, Adam C.; Singh, Simron; Siu, Lillian L.; Pugh, Trevor J.
Systemic ceramide accumulation leads to severe and varied pathological consequences
EMBO MOLECULAR MEDICINE
IF8.3
2013-05-1699
OAAI
Alayoubi, Abdulfatah M.; Wang, James C. M.; Au, Bryan C. Y.; Carpentier, Stephane; Garcia, Virginie; Dworski, Shaalee; El-Ghamrasni, Samah; Kirouac, Kevin N.; Exertier, Mathilde J.; Xiong, Zi Jian; Prive, Gilbert G.; Simonaro, Calogera M.; Casas, Josefina; Fabrias, Gemma; Schuchman, Edward H.; Turner, Patricia V.; Hakem, Razqallah; Levade, Thierry; Medin, Jeffrey A.

研究方向

暂未获取到该数据
R
Razqallah Hakem
H 指数:56论文数:160被引数:1.7万
A
Anne Hakem
H 指数:30论文数:60被引数:7,545
T
Trevor J. Pugh
H 指数:79论文数:1,292被引数:4.3万
M
M. Prakash Hande
H 指数:60论文数:265被引数:1.7万
K
Kiran Kumar Naidu Guturi
H 指数:8论文数:9被引数:385
B
Brian Raught
H 指数:75论文数:395被引数:2.9万
D
David W. Cescon
H 指数:53论文数:406被引数:1.4万
O
Otto Sánchez
H 指数:26论文数:91被引数:3,355
M
Miguel Ángel Pujana
H 指数:46论文数:351被引数:8,947
G
Grant S. Stewart
H 指数:44论文数:185被引数:8,999